Bioactivity and Bactericidal Mechanism of Histidine-Rich β-Hairpin Peptide Against Gram-Negative Bacteria

Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies

(2019) Hongxia Hu et al.   ACS Central Science

Role of Lipid Composition, Physicochemical Interactions, and Membrane Mechanics in the Molecular Actions of Microbial Cyclic Lipopeptides

(2019) Daniel Balleza et al.   JOURNAL OF MEMBRANE BIOLOGY

Mediatory roles of leukotriene B4 receptors in LPS-induced endotoxic shock

(2019) Sun-Young Kwon et al.   Scientific Reports

Highly Stabilized α-Helical Coiled Coils Kill Gram-Negative Bacteria by Multicomplementary Mechanisms under Acidic Condition

(2019) Zhenheng Lai et al.   ACS Applied Materials & Interfaces

Low-concentration exposure to glyphosate-based herbicide modulates the complexes of the mitochondrial respiratory chain and induces mitochondrial hyperpolarization in the Danio rerio brain

(2018) Aline G. Pereira et al.   CHEMOSPHERE

Recent Advances in Antibacterial and Antiendotoxic Peptides or Proteins from Marine Resources

(2018) Zhenlong Wang et al.   Marine Drugs

Surfing Motility: A Conserved yet Diverse Adaptation among Motile Bacteria

(2018) Evelyn Sun et al.   JOURNAL OF BACTERIOLOGY

An engineered arginine-rich α-helical antimicrobial peptide exhibits broad-spectrum bactericidal activity against pathogenic bacteria and reduces bacterial infections in mice

(2018) Chin-Hao Yang et al.   Scientific Reports

Protegrin 1 Enhances Innate Cellular Defense via the Insulin-Like Growth Factor 1 Receptor Pathway

(2018) Jenna Penney et al.   Frontiers in Cellular and Infection Microbiology

Bacteriocins: perspective for the development of novel anticancer drugs

(2018) Piyush Baindara et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Theoretical Insights into the Interactions between Star-Shaped Antimicrobial Polypeptides and Bacterial Membranes

(2018) Yunhan Zhang et al.   LANGMUIR

Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era

(2018) Jiajun Wang et al.   MEDICINAL RESEARCH REVIEWS

Gram-positive bacterial cell envelopes: The impact on the activity of antimicrobial peptides

(2016) Nermina Malanovic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

In Vivo Detoxification of Lipopolysaccharide by Antimicrobial Peptides

(2016) Wenxu Zhang et al.   BIOCONJUGATE CHEMISTRY

Insights into the Antimicrobial Activity and Cytotoxicity of Engineered α-Helical Peptide Amphiphiles

(2016) Zhi Ma et al.   JOURNAL OF MEDICINAL CHEMISTRY

Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

(2016) Ingrid A. Edwards et al.   ACS Infectious Diseases

Strategies employed in the design and optimization of synthetic antimicrobial peptide amphiphiles with enhanced therapeutic potentials

(2014) Zhan Yuin Ong et al.   ADVANCED DRUG DELIVERY REVIEWS

Antimicrobial potency and selectivity of simplified symmetric-end peptides

(2014) Na Dong et al.   BIOMATERIALS

Design of Embedded-Hybrid Antimicrobial Peptides with Enhanced Cell Selectivity and Anti-Biofilm Activity

(2014) Wei Xu et al.   PLoS One

Directed Evolution of an LBP/CD14 Inhibitory Peptide and Its Anti-Endotoxin Activity

(2014) Li Fang et al.   PLoS One

Design of imperfectly amphipathic α-helical antimicrobial peptides with enhanced cell selectivity

(2013) Xin Zhu et al.   Acta Biomaterialia

Preclinical Investigations Reveal the Broad-Spectrum Neutralizing Activity of Peptide Pep19-2.5 on Bacterial Pathogenicity Factors

(2013) Lena Heinbockel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic β-sheet forming peptide amphiphiles

(2013) Zhan Yuin Ong et al.   BIOMATERIALS

The helical propensity of KLA amphipathic peptides enhances their binding to gel-state lipid membranes

(2013) Ahmad Arouri et al.   BIOPHYSICAL CHEMISTRY

Collapsing the Proton Motive Force to Identify Synergistic Combinations against Staphylococcus aureus

(2013) Maya A. Farha et al.   CHEMISTRY & BIOLOGY

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Activity and selectivity of histidine-containing lytic peptides to antibiotic-resistant bacteria

(2012) Riddhi Kharidia et al.   ARCHIVES OF MICROBIOLOGY

Molecular Mechanism of Action of β-Hairpin Antimicrobial Peptide Arenicin: Oligomeric Structure in Dodecylphosphocholine Micelles and Pore Formation in Planar Lipid Bilayers

(2011) Zakhar O. Shenkarev et al.   BIOCHEMISTRY

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy

(2011) Linda Ejim et al.   Nature Chemical Biology

Designing antimicrobial peptides: form follows function

(2011) Christopher D. Fjell et al.   NATURE REVIEWS DRUG DISCOVERY

Cell selectivity, mechanism of action and LPS-neutralizing activity of bovine myeloid antimicrobial peptide-18 (BMAP-18) and its analogs

(2011) Eun Kyu Lee et al.   PEPTIDES

Inhibitory effects and mechanisms of physiological conditions on the activity of enantiomeric forms of an α-helical antibacterial peptide against bacteria

(2011) Jinfeng Huang et al.   PEPTIDES

New Antiseptic Peptides To Protect against Endotoxin-Mediated Shock

(2010) T. Gutsmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Depolarization, Bacterial Membrane Composition, and the Antimicrobial Action of Ceragenins

(2010) R. F. Epand et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibiotic-loaded biomaterials and the risks for the spread of antibiotic resistance following their prophylactic and therapeutic clinical use

(2010) Davide Campoccia et al.   BIOMATERIALS

Role of acetylation and charge in antimicrobial peptides based on human β-defensin-3

(2009) EMILIOS ANDREW PAPANASTASIOU et al.   APMIS

Effects of arginine density on the membrane-bound structure of a cationic antimicrobial peptide from solid-state NMR

(2008) Ming Tang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pili in Gram-negative and Gram-positive bacteria — structure, assembly and their role in disease

(2008) T. Proft et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Energy source of flagellar type III secretion

(2008) Koushik Paul et al.   NATURE