Protegrin 1 Enhances Innate Cellular Defense via the Insulin-Like Growth Factor 1 Receptor Pathway

TRIM29 Negatively Regulates the Type I IFN Production in Response to RNA Virus

(2018) Junji Xing et al.   JOURNAL OF IMMUNOLOGY

IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: overview and new insights

(2017) Heming Li et al.   Molecular Cancer

TRIM29 promotes DNA virus infections by inhibiting innate immune response

(2017) Junji Xing et al.   Nature Communications

XGFR*, a novel affinity-matured bispecific antibody targeting IGF-1R and EGFR with combined signaling inhibition and enhanced immune activation for the treatment of pancreatic cancer

(2016) Juergen M. Schanzer et al.   mAbs

The role of antimicrobial peptides in chronic inflammatory skin diseases

(2016) Małgorzata Marcinkiewicz et al.   Postepy Dermatologii i Alergologii

The role of the insulin-like growth factor-1 system in breast cancer

(2015) Panagiotis F Christopoulos et al.   Molecular Cancer

A role for E-cadherin in ensuring cohesive migration of a heterogeneous population of non-epithelial cells

(2015) Kyra Campbell et al.   Nature Communications

Mucin1 promotes the migration and invasion of hepatocellular carcinoma cells via JNK-mediated phosphorylation of Smad2 at the C-terminal and linker regions

(2015) Juan Wang et al.   Oncotarget

Activation of human mast cells by retrocyclin and protegrin highlight their immunomodulatory and antimicrobial properties

(2015) Kshitij Gupta et al.   Oncotarget

Co-targeting the IGF system and HIF-1 inhibits migration and invasion by (triple-negative) breast cancer cells

(2014) M Mancini et al.   BRITISH JOURNAL OF CANCER

Effect of growth factors on antimicrobial peptides and pro-inflammatory mediators during wound healing

(2014) H. Dommisch et al.   Clinical Oral Investigations

Insulin-like growth factor-1 stimulates regulatory T cells and suppresses autoimmune disease

(2014) D. Bilbao et al.   EMBO Molecular Medicine

Wound repair and regeneration: Mechanisms, signaling, and translation

(2014) S. A. Eming et al.   Science Translational Medicine

Mechanisms of Activation of Receptor Tyrosine Kinases: Monomers or Dimers

(2014) Ichiro Maruyama   Cells

Mucosal healing in inflammatory bowel disease: Treatment efficacy and predictive factors

(2013) Claudio Papi et al.   DIGESTIVE AND LIVER DISEASE

Little Peptide, Big Effects: The Role of LL-37 in Inflammation and Autoimmune Disease

(2013) J. M. Kahlenberg et al.   JOURNAL OF IMMUNOLOGY

EGFR inhibitors, MHC expression and immune responses : Can EGFR inhibitors be used as immune response modifiers?

(2012) Brian P. Pollack   OncoImmunology

Antimicrobial Protegrin-1 Forms Amyloid-Like Fibrils with Rapid Kinetics Suggesting a Functional Link

(2011) Hyunbum Jang et al.   BIOPHYSICAL JOURNAL

Erlotinib-Mediated Inhibition of EGFR Signaling Induces Metabolic Oxidative Stress through NOX4

(2011) K. P. Orcutt et al.   CANCER RESEARCH

New insights into cathelicidin modulation of adaptive immunity

(2011) Kelli Wuerth et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor

(2011) A Girnita et al.   ONCOGENE

Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians

(2011) Yongsheng Wang et al.   Therapeutic Advances in Medical Oncology

Antimicrobial Protegrin-1 Forms Ion Channels: Molecular Dynamic Simulation, Atomic Force Microscopy, and Electrical Conductance Studies

(2010) Ricardo Capone et al.   BIOPHYSICAL JOURNAL

Insulin-Like Growth Factor-I Regulation of Immune Function: A Potential Therapeutic Target in Autoimmune Diseases?

(2010) T. J. Smith   PHARMACOLOGICAL REVIEWS

Expression and characterization of antimicrobial peptides Retrocyclin-101 and Protegrin-1 in chloroplasts to control viral and bacterial infections

(2010) Seung-Bum Lee et al.   PLANT BIOTECHNOLOGY JOURNAL

Insulin-Like Growth Factor-1 Receptor Inhibition Induces a Resistance Mechanism via the Epidermal Growth Factor Receptor/HER3/AKT Signaling Pathway: Rational Basis for Cotargeting Insulin-Like Growth Factor-1 Receptor and Epidermal Growth Factor Receptor in Hepatocellular Carcinoma

(2009) C. Desbois-Mouthon et al.   CLINICAL CANCER RESEARCH

Inhibition of the Insulin-like Growth Factor-1 Receptor (IGF1R) Tyrosine Kinase as a Novel Cancer Therapy Approach

(2009) Rongshi Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

The ERK and PI3K signaling pathways mediate inhibition of insulin-like growth factor-1 receptor mRNA expression by somatostatin

(2009) Andrea Hanson et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Enhanced Resistance to Bacterial Infection in Protegrin-1 Transgenic Mice

(2008) Q. C. K. Cheung et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

ERK signaling regulates tumor promoter induced c-Jun recruitment at the Fra-1 promoter

(2008) Pavan Adiseshaiah et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS