Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes

Beyond heritability: improving discoverability in imaging genetics

(2018) Chun Chieh Fan et al.   HUMAN MOLECULAR GENETICS

Characterizing the human hippocampus in aging and Alzheimer’s disease using a computational atlas derived from ex vivo MRI and histology

(2018) Daniel H. Adler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippocampal subfields at ultra high field MRI: An overview of segmentation and measurement methods

(2017) Alessia Giuliano et al.   HIPPOCAMPUS

Methionine Sulfoxide Reductase-B3 (MsrB3) Protein Associates with Synaptic Vesicles and its Expression Changes in the Hippocampi of Alzheimer’s Disease Patients

(2017) Stephanie L. Adams et al.   JOURNAL OF ALZHEIMERS DISEASE

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

(2017) Katrina M de Lange et al.   NATURE GENETICS

Novel genetic loci associated with hippocampal volume

(2017) Derrek P. Hibar et al.   Nature Communications

Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets

(2017) Max Lam et al.   Cell Reports

Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function

(2017) Olav B. Smeland et al.   JAMA Psychiatry

Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity

(2016) Anubha Mahajan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genome-wide association study identifies 74 loci associated with educational attainment

(2016) Aysu Okbay et al.   NATURE

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

(2016) Padhraig Gormley et al.   NATURE GENETICS

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

(2016) Barbara Franke et al.   NATURE NEUROSCIENCE

Anterior hippocampus: the anatomy of perception, imagination and episodic memory

(2016) Peter Zeidman et al.   NATURE REVIEWS NEUROSCIENCE

Heritability and reliability of automatically segmented human hippocampal formation subregions

(2016) Christopher D. Whelan et al.   NEUROIMAGE

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

(2016) Cristian Pattaro et al.   Nature Communications

Distinct Genetic Influences on Cortical and Subcortical Brain Structures

(2016) Wei Wen et al.   Scientific Reports

Genome-wide association study of schizophrenia in Ashkenazi Jews

(2015) Fernando S. Goes et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline

(2015) V. A. Gault et al.   DIABETES OBESITY & METABOLISM

Chronic intestinal inflammation alters hippocampal neurogenesis

(2015) Svetlana Zonis et al.   Journal of Neuroinflammation

Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium

(2015) T G M van Erp et al.   MOLECULAR PSYCHIATRY

Common genetic variants influence human subcortical brain structures

(2015) Derrek P. Hibar et al.   NATURE

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

A computational atlas of the hippocampal formation using ex vivo , ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI

(2015) Juan Eugenio Iglesias et al.   NEUROIMAGE

A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease

(2015) M Hardin et al.   PHARMACOGENOMICS JOURNAL

Development of hippocampal subfield volumes from 4 to 22 years

(2014) Stine K. Krogsrud et al.   HUMAN BRAIN MAPPING

Disruption of the ASTN2/TRIM32 locus at 9q33.1 is a risk factor in males for autism spectrum disorders, ADHD and other neurodevelopmental phenotypes

(2014) A. C. Lionel et al.   HUMAN MOLECULAR GENETICS

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Functional organization of the hippocampal longitudinal axis

(2014) Bryan A. Strange et al.   NATURE REVIEWS NEUROSCIENCE

Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging

(2014) Laura E.M. Wisse et al.   NEUROBIOLOGY OF AGING

Genome-wide association study of primary tooth eruption identifies pleiotropic loci associated with height and craniofacial distances

(2013) Ghazaleh Fatemifar et al.   HUMAN MOLECULAR GENETICS

DPP-4 inhibitors improve cognition and brain mitochondrial function of insulin-resistant rats

(2013) Hiranya Pintana et al.   JOURNAL OF ENDOCRINOLOGY

Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene

(2013) J Gelernter et al.   MOLECULAR PSYCHIATRY

Genome-wide meta-analysis identifies new susceptibility loci for migraine

(2013) Verneri Anttila et al.   NATURE GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Boosting the Power of Schizophrenia Genetics by Leveraging New Statistical Tools

(2013) O. A. Andreassen et al.   SCHIZOPHRENIA BULLETIN

Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study

(2013) Christopher S. Carlson et al.   PLOS BIOLOGY

Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

(2013) Ole A. Andreassen et al.   PLoS Genetics

Estimation of pleiotropy between complex diseases using single-nucleotide polymorphism-derived genomic relationships and restricted maximum likelihood

(2012) S.H. Lee et al.   BIOINFORMATICS

Proteomic Analysis Identifies Dysfunction in Cellular Transport, Energy, and Protein Metabolism in Different Brain Regions of Atypical Frontotemporal Lobar Degeneration

(2012) Daniel Martins-de-Souza et al.   JOURNAL OF PROTEOME RESEARCH

Genome-wide association analysis identifies susceptibility loci for migraine without aura

(2012) Tobias Freilinger et al.   NATURE GENETICS

Common variants at 12q14 and 12q24 are associated with hippocampal volume

(2012) et al.   NATURE GENETICS

Identification of common variants associated with human hippocampal and intracranial volumes

(2012) Jason L Stein et al.   NATURE GENETICS

Guidelines for Genome-Wide Association Studies

(2012) Gregory S. Barsh et al.   PLoS Genetics

FAS-Associated Factor 1 (FAF1): Diverse functions and implications for oncogenesis

(2011) Craig W. Menges et al.   CELL CYCLE

Genome-wide association analysis of age-at-onset in Alzheimer's disease

(2011) M I Kamboh et al.   MOLECULAR PSYCHIATRY

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Hippocampal volumetrics in treatment-resistant depression and schizophrenia: The devil's in De-Tail

(2010) Jerome J. Maller et al.   HIPPOCAMPUS

Astn2, A Novel Member of the Astrotactin Gene Family, Regulates the Trafficking of ASTN1 during Glial-Guided Neuronal Migration

(2010) P. M. Wilson et al.   JOURNAL OF NEUROSCIENCE

Dact1 Is a Postsynaptic Protein Required for Dendrite, Spine, and Excitatory Synapse Development in the Mouse Forebrain

(2010) N. D. Okerlund et al.   JOURNAL OF NEUROSCIENCE

New loci associated with kidney function and chronic kidney disease

(2010) Anna Köttgen et al.   NATURE GENETICS

Automated cross-sectional and longitudinal hippocampal volume measurement in mild cognitive impairment and Alzheimer's disease

(2010) Kelvin K. Leung et al.   NEUROIMAGE

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Genome-Wide Association Study Reveals Multiple Loci Associated with Primary Tooth Development during Infancy

(2010) Demetris Pillas et al.   PLoS Genetics

Differential Targeting of the CA1 Subfield of the Hippocampal Formation by Schizophrenia and Related Psychotic Disorders

(2009) Scott A. Schobel et al.   ARCHIVES OF GENERAL PSYCHIATRY

Meta-analysis of genome-wide association studies: no efficiency gain in using individual participant data

(2009) D. Y. Lin et al.   GENETIC EPIDEMIOLOGY

The role of HRK gene in human cancer

(2009) M Nakamura et al.   ONCOGENE

Recurrent CNVs Disrupt Three Candidate Genes in Schizophrenia Patients

(2008) Terry Vrijenhoek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic Anatomy of the Hippocampus

(2008) Carol L. Thompson et al.   NEURON