Development and analysis of an adverse outcome pathway network for human neurotoxicity

Extracting and Benchmarking Emerging Adverse Outcome Pathway Knowledge

(2019) Nathan L Pollesch et al.   TOXICOLOGICAL SCIENCES

Adverse Outcome Pathways: Moving from a Scientific Concept to an Internationally Accepted Framework

(2019) Markus Hecker et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

An industry perspective: A streamlined screening strategy using alternative models for chemical assessment of developmental neurotoxicity

(2019) Jinpeng Li et al.   NEUROTOXICOLOGY

An Integrative Multi-Omics Workflow to Address Multifactorial Toxicology Experiments

(2019) Víctor González-Ruiz et al.   Metabolites

Adverse outcome pathway networks II: Network analytics

(2018) Daniel L. Villeneuve et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathway networks I: Development and applications

(2018) Dries Knapen et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

(2018) Daniel L Villeneuve et al.   TOXICOLOGICAL SCIENCES

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

(2018) Ellen Fritsche et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods

(2018) Anna Bal-Price et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

(2018) Anna Bal-Price   ALTEX-Alternatives to Animal Experimentation

Cumulative effects of antiandrogenic chemical mixtures and their relevance to human health risk assessment

(2017) Kembra L. Howdeshell et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Network neuroscience

(2017) Danielle S Bassett et al.   NATURE NEUROSCIENCE

Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

(2017) Anna Bal-Price et al.   NEUROTOXICOLOGY

WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research

(2017) Denise N Slenter et al.   NUCLEIC ACIDS RESEARCH

Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity

(2017) Anna Bal-Price et al.   PHARMACOLOGY & THERAPEUTICS

Quantitative weight of evidence to assess confidence in potential modes of action

(2017) Richard A. Becker et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Weight of evidence evaluation of a network of adverse outcome pathways linking activation of the nicotinic acetylcholine receptor in honey bees to colony death

(2017) Carlie A. LaLone et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework

(2017) Iman Hassan et al.   TOXICOLOGICAL SCIENCES

The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies

(2017) Zenggang Li et al.   Nature Communications

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities

(2016) Béla Z. Schmidt et al.   ARCHIVES OF TOXICOLOGY

Adverse outcome pathways: From research to regulation scientific workshop report

(2016) Nicole C. Kleinstreuer et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A weight of evidence assessment approach for adverse outcome pathways

(2016) Zachary A. Collier et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Using In Vitro High-Throughput Screening Data for Predicting Benzo[k]Fluoranthene Human Health Hazards

(2016) Lyle D. Burgoon et al.   RISK ANALYSIS

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use

(2016) Michael Aschner   ALTEX-Alternatives to Animal Experimentation

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

(2015) Anna Bal-Price et al.   ARCHIVES OF TOXICOLOGY

Bayesian integrated testing strategy (ITS) for skin sensitization potency assessment: a decision support system for quantitative weight of evidence and adaptive testing strategy

(2015) Joanna S. Jaworska et al.   ARCHIVES OF TOXICOLOGY

Putative adverse outcome pathways relevant to neurotoxicity

(2015) Anna Bal-Price et al.   CRITICAL REVIEWS IN TOXICOLOGY

The potential of AOP networks for reproductive and developmental toxicity assay development

(2015) Dries Knapen et al.   REPRODUCTIVE TOXICOLOGY

Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models

(2015) Luise Schultz et al.   TOXICOLOGY IN VITRO

Systems Toxicology: From Basic Research to Risk Assessment

(2014) Shana J. Sturla et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Adverse Outcome Pathway Development II: Best Practices

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Toxicity Testing in the 21st Century: A Vision and a Strategy

(2010) Daniel Krewski et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS