标题
Using Large Datasets to Understand Nanotechnology
作者
关键词
-
出版物
ADVANCED MATERIALS
Volume -, Issue -, Pages 1902798
出版商
Wiley
发表日期
2019-08-20
DOI
10.1002/adma.201902798
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- De novo design of potent and selective mimics of IL-2 and IL-15
- (2019) Daniel-Adriano Silva et al. NATURE
- Nanoparticles Containing Oxidized Cholesterol Deliver mRNA to the Liver Microenvironment at Clinically Relevant Doses
- (2019) Kalina Paunovska et al. ADVANCED MATERIALS
- Exploration of the nanomedicine-design space with high-throughput screening and machine learning
- (2019) Gokay Yamankurt et al. Nature Biomedical Engineering
- Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines
- (2019) Emily Linnane et al. NUCLEIC ACIDS RESEARCH
- Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery
- (2018) Kalina Paunovska et al. ACS Nano
- Advanced siRNA Designs Further Improve In Vivo Performance of GalNAc-siRNA Conjugates
- (2018) Donald J. Foster et al. MOLECULAR THERAPY
- A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation
- (2018) Kalina Paunovska et al. NANO LETTERS
- Quantitative self-assembly prediction yields targeted nanomedicines
- (2018) Yosi Shamay et al. NATURE MATERIALS
- Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis
- (2018) David Adams et al. NEW ENGLAND JOURNAL OF MEDICINE
- Widespread changes in transcriptome profile of human mesenchymal stem cells induced by two-dimensional nanosilicates
- (2018) James K. Carrow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toxicity and Transcriptome Sequencing (RNA-seq) Analyses of Adult Zebrafish in Response to Exposure Carboxymethyl Cellulose Stabilized Iron Sulfide Nanoparticles
- (2018) Min Zheng et al. Scientific Reports
- Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo
- (2018) Cory D. Sago et al. NANO LETTERS
- Nanoparticles That Deliver RNA to Bone Marrow Identified by in Vivo Directed Evolution
- (2018) Cory D. Sago et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Programmable design of orthogonal protein heterodimers
- (2018) Zibo Chen et al. NATURE
- High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
- (2018) Cory D. Sago et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
- (2017) Kapil Bahl et al. MOLECULAR THERAPY
- Boosting Intracellular Delivery of Lipid Nanoparticle-Encapsulated mRNA
- (2017) Siddharth Patel et al. NANO LETTERS
- The Human Cell Atlas: from vision to reality
- (2017) Orit Rozenblatt-Rosen et al. NATURE
- Evolution of a designed protein assembly encapsulating its own RNA genome
- (2017) Gabriel L. Butterfield et al. NATURE
- The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
- (2017) Ly P Vu et al. NATURE MEDICINE
- Points of Significance: Principal component analysis
- (2017) Jake Lever et al. NATURE METHODS
- Massively parallel single-nucleus RNA-seq with DroNc-seq
- (2017) Naomi Habib et al. NATURE METHODS
- Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems
- (2017) Ken Y Chan et al. NATURE NEUROSCIENCE
- Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy
- (2017) K. John Pasi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics
- (2017) James E. Dahlman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology
- (2017) Hellmut G. Augustin et al. SCIENCE
- Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors
- (2017) Alexandra-Chloé Villani et al. SCIENCE
- Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
- (2017) Nicolas Bertrand et al. Nature Communications
- Ecological interactions among Saccharomyces cerevisiae strains: insight into the dominance phenomenon
- (2017) Roberto Pérez-Torrado et al. Scientific Reports
- Cerium oxide nanoparticles inhibit differentiation of neural stem cells
- (2017) Anda R. Gliga et al. Scientific Reports
- A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
- (2017) Joy Wolfram et al. Scientific Reports
- Understanding the Kinetics of Protein–Nanoparticle Corona Formation
- (2016) Oriol Vilanova et al. ACS Nano
- Metabolic Control of Longevity
- (2016) Carlos López-Otín et al. CELL
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens
- (2016) Atray Dixit et al. CELL
- Single-cell triple omics sequencing reveals genetic, epigenetic and transcriptomic heterogeneity in hepatocellular carcinomas
- (2016) Yu Hou et al. CELL RESEARCH
- Transcriptomic and Physiological Responses of the Green Microalga Chlamydomonas reinhardtii during Short-Term Exposure to Subnanomolar Methylmercury Concentrations
- (2016) Rebecca Beauvais-Flück et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Melanoma growth effects on molecular clearance from tumors and biodistribution into systemic tissues versus draining lymph nodes
- (2016) Nathan Andrew Rohner et al. JOURNAL OF CONTROLLED RELEASE
- Emerging Frontiers in Drug Delivery
- (2016) Mark W. Tibbitt et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq
- (2016) Barbara Treutlein et al. NATURE
- Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
- (2016) Benjamin E Deverman et al. NATURE BIOTECHNOLOGY
- Mechanism of hard-nanomaterial clearance by the liver
- (2016) Kim M. Tsoi et al. NATURE MATERIALS
- Single-cell multimodal profiling reveals cellular epigenetic heterogeneity
- (2016) Lih Feng Cheow et al. NATURE METHODS
- Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity
- (2016) Christof Angermueller et al. NATURE METHODS
- Improving the efficacy and safety of biologic drugs with tolerogenic nanoparticles
- (2016) Takashi K. Kishimoto et al. Nature Nanotechnology
- Post-transcriptional gene regulation by mRNA modifications
- (2016) Boxuan Simen Zhao et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Expansion of the Gene Ontology knowledgebase and resources
- (2016) NUCLEIC ACIDS RESEARCH
- KEGG: new perspectives on genomes, pathways, diseases and drugs
- (2016) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Avoiding common pitfalls when clustering biological data
- (2016) T. Ronan et al. Science Signaling
- Aurora kinase inhibitor nanoparticles target tumors with favorable therapeutic index in vivo
- (2016) Susan Ashton et al. Science Translational Medicine
- Theranostic barcoded nanoparticles for personalized cancer medicine
- (2016) Zvi Yaari et al. Nature Communications
- Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells
- (2016) Spyros Darmanis et al. Cell Reports
- Avoiding common pitfalls when clustering biological data
- (2016) T. Ronan et al. Science Signaling
- Plasma Proteome Profiling to Assess Human Health and Disease
- (2016) Philipp E. Geyer et al. Cell Systems
- Analysis of nanoparticle delivery to tumours
- (2016) Stefan Wilhelm et al. Nature Reviews Materials
- Proteomic and Lipidomic Analysis of Nanoparticle Corona upon Contact with Lung Surfactant Reveals Differences in Protein, but Not Lipid Composition
- (2015) Simon Sebastian Raesch et al. ACS Nano
- Identification of cell types from single-cell transcriptomes using a novel clustering method
- (2015) Chen Xu et al. BIOINFORMATICS
- Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
- (2015) Sidi Chen et al. CELL
- Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets
- (2015) Evan Z. Macosko et al. CELL
- Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease
- (2015) Elizabeta Gjoneska et al. NATURE
- Integrated genome and transcriptome sequencing of the same cell
- (2015) Siddharth S Dey et al. NATURE BIOTECHNOLOGY
- Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown
- (2015) Anders Wittrup et al. NATURE BIOTECHNOLOGY
- Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates
- (2015) Omid Veiseh et al. NATURE MATERIALS
- Comparing the performance of biomedical clustering methods
- (2015) Christian Wiwie et al. NATURE METHODS
- A holistic approach to targeting disease with polymeric nanoparticles
- (2015) Christopher J. Cheng et al. NATURE REVIEWS DRUG DISCOVERY
- High-throughput functional genomics using CRISPR–Cas9
- (2015) Ophir Shalem et al. NATURE REVIEWS GENETICS
- KEGG as a reference resource for gene and protein annotation
- (2015) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
- (2015) Mona Meyer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
- (2015) A. Zeisel et al. SCIENCE
- Next-Generation Sequencing Reveals Low-Dose Effects of Cationic Dendrimers in Primary Human Bronchial Epithelial Cells
- (2014) Neus Feliu et al. ACS Nano
- Investigating the Impact of Nanoparticle Size on Active and Passive Tumor Targeting Efficiency
- (2014) Edward A. Sykes et al. ACS Nano
- Coming Full Circle—From Endless Complexity to Simplicity and Back Again
- (2014) Robert A. Weinberg CELL
- Proteogenomic characterization of human colon and rectal cancer
- (2014) Bing Zhang et al. NATURE
- Single-cell RNA-seq reveals dynamic paracrine control of cellular variation
- (2014) Alex K. Shalek et al. NATURE
- Time to deliver
- (2014) NATURE BIOTECHNOLOGY
- Microfluidic organs-on-chips
- (2014) Sangeeta N Bhatia et al. NATURE BIOTECHNOLOGY
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- Onco-proteogenomics: cancer proteomics joins forces with genomics
- (2014) Javier A Alfaro et al. NATURE METHODS
- Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
- (2014) Dmitry Usoskin et al. NATURE NEUROSCIENCE
- Microfluidic single-cell whole-transcriptome sequencing
- (2014) A. M. Streets et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells
- (2014) David T. Ting et al. Cell Reports
- Transcriptome Sequencing (RNA-seq) Analysis of the Effects of Metal Nanoparticle Exposure on the Transcriptome of Chlamydomonas reinhardtii
- (2013) D. F. Simon et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Long Noncoding RNAs: Cellular Address Codes in Development and Disease
- (2013) Pedro J. Batista et al. CELL
- The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes
- (2013) Fengjuan Wang et al. Nanomedicine-Nanotechnology Biology and Medicine
- The big challenges of big data
- (2013) Vivien Marx NATURE
- Accelerating the design of biomimetic materials by integrating RNA-seq with proteomics and materials science
- (2013) Paul A Guerette et al. NATURE BIOTECHNOLOGY
- Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape
- (2013) Jerome Gilleron et al. NATURE BIOTECHNOLOGY
- Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling
- (2013) Gaurav Sahay et al. NATURE BIOTECHNOLOGY
- Quantitative assessment of single-cell RNA-sequencing methods
- (2013) Angela R Wu et al. NATURE METHODS
- Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
- (2013) Anna Salvati et al. Nature Nanotechnology
- Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
- (2013) Ophir Shalem et al. SCIENCE
- Profiling the molecular mechanism of fullerene cytotoxicity on tumor cells by RNA-seq
- (2013) Marianna Lucafò et al. TOXICOLOGY
- Characterizing and measuring bias in sequence data
- (2013) Michael G Ross et al. GENOME BIOLOGY
- The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems
- (2012) Alexandre Albanese et al. Annual Review of Biomedical Engineering
- Human Respiratory Syncytial Virus Nucleoprotein and Inclusion Bodies Antagonize the Innate Immune Response Mediated by MDA5 and MAVS
- (2012) A. W. Lifland et al. JOURNAL OF VIROLOGY
- Performance comparison of benchtop high-throughput sequencing platforms
- (2012) Nicholas J Loman et al. NATURE BIOTECHNOLOGY
- Pharmacogenomics in clinical practice and drug development
- (2012) Andrew R Harper et al. NATURE BIOTECHNOLOGY
- Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses
- (2012) Oliver Stegle et al. Nature Protocols
- Polycation-siRNA nanoparticles can disassemble at the kidney glomerular basement membrane
- (2012) J. E. Zuckerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The ferret as a model organism to study influenza A virus infection
- (2011) J. A. Belser et al. Disease Models & Mechanisms
- Receptor-Mediated Endocytosis of Nanoparticles of Various Shapes
- (2011) Robert Vácha et al. NANO LETTERS
- Tumour evolution inferred by single-cell sequencing
- (2011) Nicholas Navin et al. NATURE
- Supervised normalization of microarrays
- (2010) Brigham H. Mecham et al. BIOINFORMATICS
- Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms
- (2010) Akin Akinc et al. MOLECULAR THERAPY
- Color coding
- (2010) Bang Wong NATURE METHODS
- Visualization of omics data for systems biology
- (2010) Nils Gehlenborg et al. NATURE METHODS
- Alternative expression analysis by RNA sequencing
- (2010) Malachi Griffith et al. NATURE METHODS
- Biases in Illumina transcriptome sequencing caused by random hexamer priming
- (2010) Kasper D. Hansen et al. NUCLEIC ACIDS RESEARCH
- 3' tag digital gene expression profiling of human brain and universal reference RNA using Illumina Genome Analyzer
- (2009) Yan W Asmann et al. BMC GENOMICS
- mRNA-Seq whole-transcriptome analysis of a single cell
- (2009) Fuchou Tang et al. NATURE METHODS
- Endocytosis and signalling: intertwining molecular networks
- (2009) Alexander Sorkin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Data clustering: 50 years beyond K-means
- (2009) Anil K. Jain PATTERN RECOGNITION LETTERS
- What is principal component analysis?
- (2008) Markus Ringnér NATURE BIOTECHNOLOGY
- What would you do if you could sequence everything?
- (2008) Avak Kahvejian et al. NATURE BIOTECHNOLOGY
- Interpreting principal component analyses of spatial population genetic variation
- (2008) John Novembre et al. NATURE GENETICS
- Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
- (2008) Emyr Lloyd-Evans et al. NATURE MEDICINE
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