标题
The Genetic Basis of Toxin Biosynthesis in Dinoflagellates
作者
关键词
-
出版物
Microorganisms
Volume 7, Issue 8, Pages 222
出版商
MDPI AG
发表日期
2019-07-29
DOI
10.3390/microorganisms7080222
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Diversified secondary metabolite biosynthesis gene repertoire revealed in symbiotic dinoflagellates
- (2019) Girish Beedessee et al. Scientific Reports
- Discovery of a New Clade Nested Within the Genus Alexandrium (Dinophyceae): Morpho-molecular Characterization of Centrodinium punctatum (Cleve) F.J.R. Taylor
- (2019) Zhun Li et al. PROTIST
- An aerobic eukaryotic parasite with functional mitochondria that likely lacks a mitochondrial genome
- (2019) Uwe John et al. Science Advances
- Progress and promise of omics for predicting the impacts of climate change on harmful algal blooms
- (2019) Gwenn M.M. Hennon et al. HARMFUL ALGAE
- Viral proteins as a potential driver of histone depletion in dinoflagellates
- (2018) Nicholas A. T. Irwin et al. Nature Communications
- Dinoflagellates, a Unique Lineage for Retrogene Research
- (2018) Bo Song et al. Frontiers in Microbiology
- RNA-Seq as an Emerging Tool for Marine Dinoflagellate Transcriptome Analysis: Process and Challenges
- (2018) Muhamad Akbar et al. Processes
- Insertions within the Saxitoxin Biosynthetic Gene Cluster Result in Differential Toxin Profiles
- (2018) Alescia Cullen et al. ACS Chemical Biology
- iTRAQ-Based Quantitative Proteomic Analysis of a Toxigenic Dinoflagellate Alexandrium catenella at Different Stages of Toxin Biosynthesis during the Cell Cycle
- (2018) Shu-Fei Zhang et al. Marine Drugs
- Core genes in diverse dinoflagellate lineages include a wealth of conserved dark genes with unknown functions
- (2018) Timothy G. Stephens et al. Scientific Reports
- qPCR Assays for the Detection and Quantification of Multiple Paralytic Shellfish Toxin-Producing Species of Alexandrium
- (2018) Rendy Ruvindy et al. Frontiers in Microbiology
- Comparative Genomics Reveals Two Major Bouts of Gene Retroposition Coinciding with Crucial Periods of Symbiodinium Evolution
- (2017) Bo Song et al. Genome Biology and Evolution
- Transcriptomic and microRNAomic profiling reveals multi-faceted mechanisms to cope with phosphate stress in a dinoflagellate
- (2017) Xinguo Shi et al. ISME Journal
- Role of Modular Polyketide Synthases in the Production of Polyether Ladder Compounds in Ciguatoxin-Producing Gambierdiscus polynesiensis and G. excentricus (Dinophyceae)
- (2017) Gurjeet S. Kohli et al. JOURNAL OF EUKARYOTIC MICROBIOLOGY
- Both modular and single-domain Type I polyketide synthases are expressed in the brevetoxin-producing dinoflagellate, Karenia brevis (Dinophyceae)
- (2017) Frances M. Van Dolah et al. JOURNAL OF PHYCOLOGY
- Whole Transcriptomic Analysis Provides Insights into Molecular Mechanisms for Toxin Biosynthesis in a Toxic Dinoflagellate Alexandrium catenella (ACHK-T)
- (2017) et al. Toxins
- Predator cues reduce intraspecific trait variability in a marine dinoflagellate
- (2017) Sylke Wohlrab et al. BMC ECOLOGY
- miRNAs Do Not Regulate Circadian Protein Synthesis in the Dinoflagellate Lingulodinium polyedrum
- (2017) Steve Dagenais-Bellefeuille et al. PLoS One
- Quantity of the dinoflagellate sxtA4 gene and cell density correlates with paralytic shellfish toxin production in Alexandrium ostenfeldii blooms
- (2016) Henna Savela et al. HARMFUL ALGAE
- Physiological and transcriptional responses to inorganic nutrition in a tropical Pacific strain of Alexandrium minutum: Implications for the saxitoxin genes and toxin production
- (2016) Kieng Soon Hii et al. HARMFUL ALGAE
- Evolutionary distinctiveness of fatty acid and polyketide synthesis in eukaryotes
- (2016) Gurjeet S Kohli et al. ISME Journal
- Paralytic shellfish toxin biosynthesis in cyanobacteria and dinoflagellates: A molecular overview
- (2016) Da-Zhi Wang et al. Journal of Proteomics
- Molecular Detection of theSxtaGene from Saxitoxin-ProducingAlexandrium minutumin Commercial Oysters
- (2016) Hazel Farrell et al. JOURNAL OF SHELLFISH RESEARCH
- Major transitions in dinoflagellate evolution unveiled by phylotranscriptomics
- (2016) Jan Janouškovec et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptomic characterisation and genomic glimps into the toxigenic dinoflagellate Azadinium spinosum, with emphasis on polykeitde synthase genes
- (2015) Jan M Meyer et al. BMC GENOMICS
- Multimodular type I polyketide synthases in algae evolve by module duplications and displacement of AT domains in trans
- (2015) Ekaterina Shelest et al. BMC GENOMICS
- Polyketide synthesis genes associated with toxin production in two species of Gambierdiscus (Dinophyceae)
- (2015) Gurjeet S. Kohli et al. BMC GENOMICS
- Multifunctional polyketide synthase genes identified by genomic survey of the symbiotic dinoflagellate, Symbiodinium minutum
- (2015) Girish Beedessee et al. BMC GENOMICS
- Global patterns of pelagic dinoflagellate diversity across protist size classes unveiled by metabarcoding
- (2015) Noan Le Bescot et al. ENVIRONMENTAL MICROBIOLOGY
- The sxt Gene and Paralytic Shellfish Poisoning Toxins as Markers for the Monitoring of Toxic Alexandrium Species Blooms
- (2015) Antonella Penna et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Metatranscriptome profiling reveals versatile N-nutrient utilization, CO2 limitation, oxidative stress, and active toxin production in an Alexandrium fundyense bloom
- (2015) Yunyun Zhuang et al. HARMFUL ALGAE
- Spatial distribution of toxic Alexandrium tamiyavanichii (Dinophyceae) in the southeastern South China Sea-Sulu Sea: A molecular-based assessment using real-time quantitative PCR (qPCR) assay
- (2015) Nyuk Fong Kon et al. HARMFUL ALGAE
- Biosynthetic Studies of 13-Desmethylspirolide C Produced by Alexandrium ostenfeldii (= A. peruvianum): Rationalization of the Biosynthetic Pathway Following Incorporation of 13C-Labeled Methionine and Application of the Odd–Even Rule of Methylation
- (2015) Matthew Anttila et al. JOURNAL OF NATURAL PRODUCTS
- Distribution of Alexandrium fundyense and A. pacificum (Dinophyceae) in the Yellow Sea and Bohai Sea
- (2015) Yan Gao et al. MARINE POLLUTION BULLETIN
- Gene duplication, loss and selection in the evolution of saxitoxin biosynthesis in alveolates
- (2015) Shauna A. Murray et al. MOLECULAR PHYLOGENETICS AND EVOLUTION
- Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins
- (2015) Craig E. Stivala et al. NATURAL PRODUCT REPORTS
- Identification of microRNAs in the Toxigenic Dinoflagellate Alexandrium catenella by High-Throughput Illumina Sequencing and Bioinformatic Analysis
- (2015) Huili Geng et al. PLoS One
- Eukaryotic plankton diversity in the sunlit ocean
- (2015) C. de Vargas et al. SCIENCE
- The Symbiodinium kawagutii genome illuminates dinoflagellate gene expression and coral symbiosis
- (2015) S. Lin et al. SCIENCE
- Diversity and Divergence of Dinoflagellate Histone Proteins
- (2015) Georgi K. Marinov et al. G3-Genes Genomes Genetics
- Paralytic shellfish toxin content is related to genomic sxtA4 copy number in Alexandrium minutum strains
- (2015) Anke Stüken et al. Frontiers in Microbiology
- RNA Sequencing Revealed Numerous Polyketide Synthase Genes in the Harmful Dinoflagellate Karenia mikimotoi
- (2015) Kei Kimura et al. PLoS One
- Transcriptome sequencing reveals single domain Type I-like polyketide synthases in the toxic dinoflagellate Gambierdiscus polynesiensis
- (2014) R. Pawlowiez et al. HARMFUL ALGAE
- Comparative Transcriptome Analysis of a Toxin-Producing Dinoflagellate Alexandrium catenella and Its Non-Toxic Mutant
- (2014) Yong Zhang et al. Marine Drugs
- SxtA and sxtG Gene Expression and Toxin Production in the Mediterranean Alexandrium minutum (Dinophyceae)
- (2014) Federico Perini et al. Marine Drugs
- Synthesis and identification of proposed biosynthetic intermediates of saxitoxin in the cyanobacterium Anabaena circinalis (TA04) and the dinoflagellate Alexandrium tamarense (Axat-2)
- (2014) Shigeki Tsuchiya et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Formal Revision of the Alexandrium tamarense Species Complex (Dinophyceae) Taxonomy: The Introduction of Five Species with Emphasis on Molecular-based (rDNA) Classification
- (2014) Uwe John et al. PROTIST
- Gene expression and molecular evolution of sxtA4 in a saxitoxin producing dinoflagellate Alexandrium catenella
- (2014) Maria Wiese et al. TOXICON
- The Marine Microbial Eukaryote Transcriptome Sequencing Project (MMETSP): Illuminating the Functional Diversity of Eukaryotic Life in the Oceans through Transcriptome Sequencing
- (2014) Patrick J. Keeling et al. PLOS BIOLOGY
- Evolutionary Acquisition and Loss of Saxitoxin Biosynthesis in Dinoflagellates: the Second “Core” Gene,sxtG
- (2013) Russell J. S. Orr et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Integrating microRNA and mRNA expression profiling in Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals
- (2013) Sebastian Baumgarten et al. BMC GENOMICS
- Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene
- (2013) Shilah A. Bonnett et al. CHEMISTRY & BIOLOGY
- Draft Assembly of the Symbiodinium minutum Nuclear Genome Reveals Dinoflagellate Gene Structure
- (2013) Eiichi Shoguchi et al. CURRENT BIOLOGY
- Computational Identification of MicroRNAs from the Expressed Sequence Tags of Toxic Dinoflagellate Alexandrium Tamarense
- (2013) Dahai Gao et al. Evolutionary Bioinformatics
- Paralytic shellfish toxins or spirolides? The role of environmental and genetic factors in toxin production of the Alexandrium ostenfeldii complex
- (2013) Sanna Suikkanen et al. HARMFUL ALGAE
- Novel hydrolysis-probe based qPCR assay to detect saxitoxin transcripts of dinoflagellates in environmental samples
- (2013) Anke Stüken et al. HARMFUL ALGAE
- Subcellular localization of dinoflagellate polyketide synthases and fatty acid synthase activity
- (2013) Frances M. Van Dolah et al. JOURNAL OF PHYCOLOGY
- Osmotic stress does not trigger brevetoxin production in the dinoflagellate Karenia brevis
- (2013) W. G. Sunda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genomics-Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human PathogenicBurkholderiaSpecies
- (2012) Jakob Franke et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Loss of Nucleosomal DNA Condensation Coincides with Appearance of a Novel Nuclear Protein in Dinoflagellates
- (2012) Sebastian G. Gornik et al. CURRENT BIOLOGY
- Quantitative proteomic analysis of differentially expressed proteins in the toxicity-lost mutant of Alexandrium catenella (Dinophyceae) in the exponential phase
- (2012) Da-Zhi Wang et al. Journal of Proteomics
- Dozens of Toxin-Related Genes Are Expressed in a Nontoxic Strain of the Dinoflagellate Heterocapsa circularisquama
- (2012) Tovah Salcedo et al. MOLECULAR BIOLOGY AND EVOLUTION
- Evolution of Saxitoxin Synthesis in Cyanobacteria and Dinoflagellates
- (2012) Jeremiah D. Hackett et al. MOLECULAR BIOLOGY AND EVOLUTION
- The structures of type I polyketide synthases
- (2012) Adrian T. Keatinge-Clay NATURAL PRODUCT REPORTS
- A Full Suite of Histone and Histone Modifying Genes Are Transcribed in the Dinoflagellate Lingulodinium
- (2012) Sougata Roy et al. PLoS One
- Putative Monofunctional Type I Polyketide Synthase Units: A Dinoflagellate-Specific Feature?
- (2012) Karsten Eichholz et al. PLoS One
- Dinoflagellate tandem array gene transcripts are highly conserved and not polycistronic
- (2012) M. Beauchemin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Rise of Chemodiversity in Plants
- (2012) J.-K. Weng et al. SCIENCE
- A quantitative review of the lifestyle, habitat and trophic diversity of dinoflagellates (Dinoflagellata, Alveolata)
- (2012) Fernando Gómez SYSTEMATICS AND BIODIVERSITY
- Progress in Understanding Harmful Algal Blooms: Paradigm Shifts and New Technologies for Research, Monitoring, and Management
- (2011) Donald M. Anderson et al. Annual Review of Marine Science
- sxtA-Based Quantitative Molecular Assay To Identify Saxitoxin-Producing Harmful Algal Blooms in Marine Waters
- (2011) Shauna A. Murray et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Transcriptomic response of the red tide dinoflagellate, Karenia brevis, to nitrogen and phosphorus depletion and addition
- (2011) Jeanine S Morey et al. BMC GENOMICS
- Improved phylogenetic resolution of toxic and non-toxic Alexandrium strains using a concatenated rDNA approach
- (2011) Russell J.S. Orr et al. HARMFUL ALGAE
- The globally distributed genus Alexandrium: Multifaceted roles in marine ecosystems and impacts on human health
- (2011) Donald M. Anderson et al. HARMFUL ALGAE
- Post-transcriptional Regulation of S-Phase Genes in the Dinoflagellate, Karenia brevis
- (2011) STEPHANIE A. BRUNELLE et al. JOURNAL OF EUKARYOTIC MICROBIOLOGY
- The Relevance of Marine Chemical Ecology to Plankton and Ecosystem Function: An Emerging Field
- (2011) Adrianna Ianora et al. Marine Drugs
- Toxicity and nutritional inadequacy of Karenia brevis: synergistic mechanisms disrupt top-down grazer control
- (2011) RJ Waggett et al. MARINE ECOLOGY PROGRESS SERIES
- Transcriptome remodeling associated with chronological aging in the dinoflagellate, Karenia brevis
- (2011) Jillian G. Johnson et al. Marine Genomics
- A Putative Gene Cluster from a Lyngbya wollei Bloom that Encodes Paralytic Shellfish Toxin Biosynthesis
- (2011) Troco K. Mihali et al. PLoS One
- Discovery of Nuclear-Encoded Genes for the Neurotoxin Saxitoxin in Dinoflagellates
- (2011) Anke Stüken et al. PLoS One
- Comparative Genomic and Transcriptomic Characterization of the Toxigenic Marine Dinoflagellate Alexandrium ostenfeldii
- (2011) Nina Jaeckisch et al. PLoS One
- Genomic understanding of dinoflagellates
- (2011) Senjie Lin RESEARCH IN MICROBIOLOGY
- Occurrence of 12-methylgymnodimine in a spirolide-producing dinoflagellate Alexandrium peruvianum and the biogenetic implications
- (2011) Ryan M. Van Wagoner et al. TETRAHEDRON LETTERS
- Emerging food contaminants: a review
- (2010) Lina Kantiani et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Dinoflagellate Genome Evolution
- (2010) Jennifer H. Wisecaver et al. Annual Review of Microbiology
- Comparative gene expression in toxic versus non-toxic strains of the marine dinoflagellate Alexandrium minutum
- (2010) Ines Yang et al. BMC GENOMICS
- CHARACTERIZATION AND EXPRESSION OF NUCLEAR-ENCODED POLYKETIDE SYNTHASES IN THE BREVETOXIN-PRODUCING DINOFLAGELLATE KARENIA BREVIS1
- (2010) Emily A. Monroe et al. JOURNAL OF PHYCOLOGY
- OCEAN CLIMATE CHANGE, PHYTOPLANKTON COMMUNITY RESPONSES, AND HARMFUL ALGAL BLOOMS: A FORMIDABLE PREDICTIVE CHALLENGE
- (2010) Gustaaf M. Hallegraeff JOURNAL OF PHYCOLOGY
- Neurotoxic Alkaloids: Saxitoxin and Its Analogs
- (2010) Maria Wiese et al. Marine Drugs
- Biosynthesis and Molecular Genetics of Polyketides in Marine Dinoflagellates
- (2010) Ralf Kellmann et al. Marine Drugs
- Extraordinary Conservation, Gene Loss, and Positive Selection in the Evolution of an Ancient Neurotoxin
- (2010) Shauna A. Murray et al. MOLECULAR BIOLOGY AND EVOLUTION
- Biosynthesis of polyketides by trans-AT polyketide synthases
- (2010) Jörn Piel NATURAL PRODUCT REPORTS
- The Smallest Known Genomes of Multicellular and Toxic Cyanobacteria: Comparison, Minimal Gene Sets for Linked Traits and the Evolutionary Implications
- (2010) Karina Stucken et al. PLoS One
- The Biosynthetic Logic of Polyketide Diversity
- (2009) Christian Hertweck ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Dinoflagellate mitochondrial genomes: stretching the rules of molecular biology
- (2009) Ross F. Waller et al. BIOESSAYS
- Characterisation of the paralytic shellfish toxin biosynthesis gene clusters in Anabaena circinalis AWQC131C and Aphanizomenon sp. NH-5
- (2009) Troco K Mihali et al. BMC BIOCHEMISTRY
- A quantitative real-time PCR assay for the identification and enumeration of Alexandrium cysts in marine sediments
- (2009) D.L. Erdner et al. DEEP-SEA RESEARCH PART II-TOPICAL STUDIES IN OCEANOGRAPHY
- Analysis of rRNA gene content in the Mediterranean dinoflagellate Alexandrium catenella and Alexandrium taylori: implications for the quantitative real-time PCR-based monitoring methods
- (2009) Luca Galluzzi et al. JOURNAL OF APPLIED PHYCOLOGY
- Characterization and Localization of a Hybrid Non-ribosomal Peptide Synthetase and Polyketide Synthase Gene from the Toxic Dinoflagellate Karenia brevis
- (2009) Susanna López-Legentil et al. MARINE BIOTECHNOLOGY
- Dinoflagellate Spliced Leader RNA Genes Display a Variety of Sequences and Genomic Arrangements
- (2009) H. Zhang et al. MOLECULAR BIOLOGY AND EVOLUTION
- Origins and functional impact of copy number variation in the human genome
- (2009) Donald F. Conrad et al. NATURE
- Evolution of metabolic diversity: Insights from microbial polyketide synthases
- (2009) Holger Jenke-Kodama et al. PHYTOCHEMISTRY
- Origin of Saxitoxin Biosynthetic Genes in Cyanobacteria
- (2009) Ahmed Moustafa et al. PLoS One
- Distinct Gene Number-Genome Size Relationships for Eukaryotes and Non-Eukaryotes: Gene Content Estimation for Dinoflagellate Genomes
- (2009) Yubo Hou et al. PLoS One
- Biosynthesis of toxic naturally-occurring seafood contaminants
- (2009) John A. Kalaitzis et al. TOXICON
- Biosynthetic Intermediate Analysis and Functional Homology Reveal a Saxitoxin Gene Cluster in Cyanobacteria
- (2008) R. Kellmann et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Widespread recycling of processed cDNAs in dinoflagellates
- (2008) Claudio H. Slamovits et al. CURRENT BIOLOGY
- Protists are microbes too: a perspective
- (2008) David A Caron et al. ISME Journal
- Nuclear Genome Sequence Survey of the DinoflagellateHeterocapsa triquetra
- (2008) MICHELLE McEWAN et al. JOURNAL OF EUKARYOTIC MICROBIOLOGY
- The remarkable chloroplast genome of dinoflagellates
- (2008) C. J. Howe et al. JOURNAL OF EXPERIMENTAL BOTANY
- Neurotoxins from Marine Dinoflagellates: A Brief Review
- (2008) Da-Zhi Wang Marine Drugs
- Anti-grazing properties of the toxic dinoflagellate Karlodinium veneficum during predator–prey interactions with the copepod Acartia tonsa
- (2008) RJ Waggett et al. MARINE ECOLOGY PROGRESS SERIES
- Marine natural products
- (2008) John W. Blunt et al. NATURAL PRODUCT REPORTS
- Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection
- (2008) TuAnh Nguyen et al. NATURE BIOTECHNOLOGY
- From Stop to Start: Tandem Gene Arrangement, Copy Number and Trans-Splicing Sites in the Dinoflagellate Amphidinium carterae
- (2008) Tsvetan R. Bachvaroff et al. PLoS One
- The Toxic Dinoflagellate Karenia brevis Encodes Novel Type I-like Polyketide Synthases Containing Discrete Catalytic Domains
- (2008) Emily A. Monroe et al. PROTIST
- Novel Insights into Evolution of Protistan Polyketide Synthases through Phylogenomic Analysis
- (2007) Uwe John et al. PROTIST
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