标题
Targeting the Tumor Microenvironment in Renal Cell Cancer Biology and Therapy
作者
关键词
-
出版物
Frontiers in Oncology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-06-14
DOI
10.3389/fonc.2019.00490
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma
- (2019) Brian I. Rini et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy
- (2019) Anping Li et al. Journal of Hematology & Oncology
- High IDO-1 expression in tumor endothelial cells is associated with response to immunotherapy in metastatic renal cell carcinoma
- (2018) Andreas Seeber et al. CANCER SCIENCE
- Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment
- (2018) Elham Azizi et al. CELL
- First-line vascular endothelial growth factor targeted therapy in renal cell carcinoma: priming the tumor microenvironment for immunotherapy
- (2018) Nizar Tannir et al. CURRENT MEDICAL RESEARCH AND OPINION
- Contribution of Tumor Endothelial Cells in Cancer Progression
- (2018) Kyoko Hida et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Axitinib in combination with pembrolizumab in patients with advanced renal cell cancer: a non-randomised, open-label, dose-finding, and dose-expansion phase 1b trial
- (2018) Michael B Atkins et al. LANCET ONCOLOGY
- Phenotype molding of stromal cells in the lung tumor microenvironment
- (2018) Diether Lambrechts et al. NATURE MEDICINE
- Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma
- (2018) David F. McDermott et al. NATURE MEDICINE
- Endothelial Cell Metabolism in Health and Disease
- (2018) Katerina Rohlenova et al. TRENDS IN CELL BIOLOGY
- An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors
- (2018) Tao Wang et al. Cancer Discovery
- The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
- (2018) Christopher J. Ricketts et al. Cell Reports
- Targeting newly identified ERβ/TGFβ-1/SMAD3 signals with the FDA-approved antiestrogen Faslodex or an ERβ selective antagonist in renal cell carcinoma
- (2018) Wenbin Song et al. Molecular Oncology
- Vessel pruning or healing: endothelial metabolism as a novel target?
- (2017) Anna Rita Cantelmo et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
- (2017) Frederick Arce Vargas et al. IMMUNITY
- Synergies of Targeting Tumor Angiogenesis and Immune Checkpoints in Non-Small Cell Lung Cancer and Renal Cell Cancer: From Basic Concepts to Clinical Reality
- (2017) Andreas Pircher et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Phenotypical change of tumor-associated macrophages in metastatic lesions of clear cell renal cell carcinoma
- (2017) Takanobu Motoshima et al. Medical Molecular Morphology
- Infiltrating mast cells promote renal cell carcinoma angiogenesis by modulating PI3K→AKT→GSK3β→AM signaling
- (2017) Y Chen et al. ONCOGENE
- Role of tumor microenvironment in tumorigenesis
- (2017) Maonan Wang et al. Journal of Cancer
- Tumor Infiltrating Mast Cells (TIMs) Confers a Marked Survival Advantage in Nonmetastatic Clear-Cell Renal Cell Carcinoma
- (2016) Hangcheng Fu et al. ANNALS OF SURGICAL ONCOLOGY
- Tim-3 Expression on Tumor-Infiltrating PD-1 + CD8 + T Cells Correlates with Poor Clinical Outcome in Renal Cell Carcinoma
- (2016) Clémence Granier et al. CANCER RESEARCH
- Fibroblast activation protein predicts prognosis in clear cell renal cell carcinoma
- (2016) José I. López et al. HUMAN PATHOLOGY
- Nestin expression on tumour vessels and tumour-infiltrating macrophages define a poor prognosis subgroup of pt1 clear cell renal cell carcinoma
- (2016) Jérôme Cros et al. VIRCHOWS ARCHIV
- Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma
- (2016) Jeffrey J. Wallin et al. Nature Communications
- Biomarkers of evasive resistance predict disease progression in cancer patients treated with antiangiogenic therapies
- (2016) Andreas Pircher et al. Oncotarget
- Androgen receptor (AR) signaling promotes RCC progression via increased endothelial cell proliferation and recruitment by modulating AKT → NF-κB → CXCL5 signaling
- (2016) Zhenfeng Guan et al. Scientific Reports
- The Contribution of Angiogenesis to the Process of Metastasis
- (2015) Diane R. Bielenberg et al. CANCER JOURNAL
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer
- (2015) N. A. Giraldo et al. CLINICAL CANCER RESEARCH
- Molecular Subtypes of Clear Cell Renal Cell Carcinoma Are Associated with Sunitinib Response in the Metastatic Setting
- (2015) B. Beuselinck et al. CLINICAL CANCER RESEARCH
- Modes of cancer cell invasion and the role of the microenvironment
- (2015) Andrew G Clark et al. CURRENT OPINION IN CELL BIOLOGY
- International Variations and Trends in Renal Cell Carcinoma Incidence and Mortality
- (2015) Ariana Znaor et al. EUROPEAN UROLOGY
- Predicting prognosis and therapeutic response from interactions between lymphocytes and tumor cells
- (2015) David A. Quigley et al. Molecular Oncology
- Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
- (2015) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer-associated fibroblasts promote renal cell carcinoma progression
- (2015) Yunze Xu et al. TUMOR BIOLOGY
- Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
- (2015) Leticia Corrales et al. Cell Reports
- Prognostic and theranostic impact of molecular subtypes and immune classifications in renal cell cancer (RCC) and colorectal cancer (CRC)
- (2015) Etienne Becht et al. OncoImmunology
- Molecular Profiling Reveals a Tumor-Promoting Phenotype of Monocytes and Macrophages in Human Cancer Progression
- (2014) Manesh Chittezhath et al. IMMUNITY
- Fibroblast heterogeneity in the cancer wound
- (2014) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Emerging role of tumor-associated macrophages as therapeutic targets in patients with metastatic renal cell carcinoma
- (2013) Matteo Santoni et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Oncology Meets Immunology: The Cancer-Immunity Cycle
- (2013) Daniel S. Chen et al. IMMUNITY
- Clinical value of circulating endothelial cell detection in oncology
- (2012) Jaco Kraan et al. DRUG DISCOVERY TODAY
- SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer
- (2012) Chu-An Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- Levels of circulating CD45dimCD34+VEGFR2+ progenitor cells correlate with outcome in metastatic renal cell carcinoma patients treated with tyrosine kinase inhibitors
- (2011) F Farace et al. BRITISH JOURNAL OF CANCER
- Knockdown of VEGF receptor-1 (VEGFR-1) impairs macrophage infiltration, angiogenesis and growth of clear cell renal cell carcinoma (CRCC)
- (2011) Chenghai Li et al. CANCER BIOLOGY & THERAPY
- Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway
- (2011) I. Daurkin et al. CANCER RESEARCH
- Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma
- (2011) Yoshihiro Komohara et al. CANCER SCIENCE
- Vascular Endothelial Growth Factor–Targeted Therapies in Advanced Renal Cell Carcinoma
- (2011) Laurence Albiges et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Biomarkers in Tumor Angiogenesis and Anti-Angiogenic Therapy
- (2011) Andreas Pircher et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Bevacizumab can induce reactivity to VEGF-C and -D in human brain and tumour derived endothelial cells
- (2011) S. Grau et al. JOURNAL OF NEURO-ONCOLOGY
- The lymphatic vasculature in disease
- (2011) Kari Alitalo NATURE MEDICINE
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- Complexity of tumor vasculature in clear cell renal cell carcinoma
- (2010) Chao-Nan Qian et al. CANCER
- Cytogenetic Abnormalities of Tumor-Associated Endothelial Cells in Human Malignant Tumors
- (2009) Tomoshige Akino et al. AMERICAN JOURNAL OF PATHOLOGY
- Increased numbers of small circulating endothelial cells in renal cell cancer patients treated with sunitinib
- (2009) Laura Vroling et al. ANGIOGENESIS
- Mast cells in tumor growth: Angiogenesis, tissue remodelling and immune-modulation
- (2009) Steven Maltby et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Role of cytokine therapy for Renal Cell Carcinoma in the era of targeted agents
- (2009) Sebastien J. Hotte et al. Current Oncology
- Angiogenesis in renal cell carcinoma: The role of tumor-associated macrophages
- (2009) Hiroshi Toge et al. INTERNATIONAL JOURNAL OF UROLOGY
- The lack of correlation between mast cells and microvessel density with pathologic feature of renal cell carcinoma
- (2009) Mohammad Ghassem Mohseni et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): A literature review
- (2008) Kiran Gupta et al. CANCER TREATMENT REVIEWS
- Sunitinib Reverses Type-1 Immune Suppression and Decreases T-Regulatory Cells in Renal Cell Carcinoma Patients
- (2008) J. H. Finke et al. CLINICAL CANCER RESEARCH
- The tumor microenvironment and its contribution to tumor evolution toward metastasis
- (2008) Girieca Lorusso et al. HISTOCHEMISTRY AND CELL BIOLOGY
- 5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
- (2008) Hendrik Poeck et al. NATURE MEDICINE
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