Keratin 6, 16 and 17—Critical Barrier Alarmin Molecules in Skin Wounds and Psoriasis

Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense

(2019) Stella X. Chen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Keratin scaffolds with human adipose stem cells: Physical and biological effects toward wound healing

(2019) Che‐Wei Lin et al.   Journal of Tissue Engineering and Regenerative Medicine

Type1 Interferons Potential Initiating Factors Linking Skin Wounds With Psoriasis Pathogenesis

(2019) Ling-juan Zhang   Frontiers in Immunology

Psoriasis: from Pathogenesis to Targeted Therapies

(2018) Curdin Conrad et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

E3 ligase Trim21 ubiquitylates and stabilizes Keratin 17 to induce STAT3 activation in psoriasis

(2018) Luting Yang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Types I and II Keratin Intermediate Filaments

(2018) Justin T. Jacob et al.   Cold Spring Harbor Perspectives in Biology

Gallic acid inhibits the expression of keratin 16 and keratin 17 through Nrf2 in psoriasis-like skin disease

(2018) Jinwei Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Keratin 6 regulates collective keratinocyte migration by altering cell–cell and cell–matrix adhesion

(2018) Fengrong Wang et al.   JOURNAL OF CELL BIOLOGY

Vascular endothelial growth factor driving aberrant keratin expression pattern contributes to the pathogenesis of psoriasis

(2017) Man Jiang et al.   EXPERIMENTAL CELL RESEARCH

IL-1 Receptor–Knockout Mice Develop Epidermal Cysts and Show an Altered Innate Immune Response after Exposure to UVB Radiation

(2017) Nikhil N. Kulkarni et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease

(2017) Christopher G. Bunick et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TGFβ/SMAD/microRNA-486-3p Signaling Axis Mediates Keratin 17 Expression and Keratinocyte Hyperproliferation in Psoriasis

(2017) Man Jiang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17

(2017) Luting Yang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Molecular Revolution in Cutaneous Biology: Keratin Genes and their Associated Disease: Diversity, Opportunities, and Challenges

(2017) Pierre A. Coulombe   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The role of allogenic keratin-derived dressing in wound healing in a mouse model

(2017) Marek Konop et al.   WOUND REPAIR AND REGENERATION

Antimicrobial peptides

(2016) Ling-juan Zhang et al.   CURRENT BIOLOGY

Keratins Are Going Nuclear

(2016) Ryan P. Hobbs et al.   DEVELOPMENTAL CELL

Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury

(2016) Ling-juan Zhang et al.   IMMUNITY

dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration

(2015) Amanda M. Nelson et al.   Cell Stem Cell

Keratins in health and disease

(2015) Diana M Toivola et al.   CURRENT OPINION IN CELL BIOLOGY

Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes

(2015) Byung Min Chung et al.   JOURNAL OF CELL BIOLOGY

Toll-Like Receptor 3 Activation Is Required for Normal Skin Barrier Repair Following UV Damage

(2015) Andrew W. Borkowski et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes

(2015) Ryan P Hobbs et al.   NATURE GENETICS

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

(2015) Xianyong Yin et al.   Nature Communications

Biomarkers of An Autoimmune Skin Disease—Psoriasis

(2015) Shan Jiang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Double-Stranded RNA Induces an Antiviral Defense Status in Epidermal Keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-Mediated Differential Signaling

(2014) B. N. Kalali et al.   JOURNAL OF IMMUNOLOGY

Innate Immune Sensors Stimulate Inflammatory and Immunosuppressive Responses to UVB Radiation

(2014) Richard L. Gallo et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Epidermal Differentiation in Barrier Maintenance and Wound Healing

(2014) Tongyu Cao Wikramanayake et al.   Advances in Wound Care

Keratin intermediate filament proteins – novel regulators of inflammation and immunity in skin

(2013) Ryan P. Hobbs et al.   JOURNAL OF CELL SCIENCE

Keratin 17: A Critical Player in the Pathogenesis of Psoriasis

(2013) Liang Jin et al.   MEDICINAL RESEARCH REVIEWS

Distinct fibroblast lineages determine dermal architecture in skin development and repair

(2013) Ryan R. Driskell et al.   NATURE

Transcriptional Control of the Differentiation Program of Interfollicular Epidermal Keratinocytes

(2012) Rose-Anne Romano et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

 Np63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

(2012) R.-A. Romano et al.   DEVELOPMENT

Identification of Novel Interaction between Annexin A2 and Keratin 17

(2012) Byung-Min Chung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tracing epithelial stem cells during development, homeostasis, and repair

(2012) Alexandra Van Keymeulen et al.   JOURNAL OF CELL BIOLOGY

A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair

(2012) Jeremy D. Rotty et al.   JOURNAL OF CELL BIOLOGY

Deletion of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity

(2012) L. Wallace et al.   JOURNAL OF CELL SCIENCE

Structural basis for heteromeric assembly and perinuclear organization of keratin filaments

(2012) Chang-Hun Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Pro-Inflammatory Cytokine IL-22 Up-Regulates Keratin 17 Expression in Keratinocytes via STAT3 and ERK1/2

(2012) Wei Zhang et al.   PLoS One

Keratin dressings speed epithelialization of deep partial-thickness wounds

(2012) Patricia M. Pechter et al.   WOUND REPAIR AND REGENERATION

Development and Homeostasis of the Skin Epidermis

(2012) P. A. Sotiropoulou et al.   Cold Spring Harbor Perspectives in Biology

Inhibition of keratin 17 expression with antisense and RNAi strategies: exploring novel therapy for psoriasis

(2011) Ting Chang et al.   EXPERIMENTAL DERMATOLOGY

IL-17A Upregulates Keratin 17 Expression in Keratinocytes through STAT1- and STAT3-Dependent Mechanisms

(2011) Xiaowei Shi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells

(2011) Hunain Alam et al.   MOLECULAR BIOLOGY OF THE CELL

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin

(2010) Daryle DePianto et al.   NATURE GENETICS

Intermediate filaments: primary determinants of cell architecture and plasticity

(2009) Harald Herrmann et al.   JOURNAL OF CLINICAL INVESTIGATION

First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder

(2009) Sancy A Leachman et al.   MOLECULAR THERAPY

Commensal bacteria regulate Toll-like receptor 3–dependent inflammation after skin injury

(2009) Yuping Lai et al.   NATURE MEDICINE

From conventional to cutting edge: the new era of biologics in treatment of psoriasis

(2008) Julia Tzu et al.   Dermatologic Therapy

A gene signature of nonhealing venous ulcers: Potential diagnostic markers

(2008) Carlos A. Charles et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY