Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21

A new therapeutic target: the CD69-Myl9 system in immune responses

(2019) Motoko Y. Kimura et al.   Seminars in Immunopathology

Oncolytic Viruses for Multiple Myeloma Therapy

(2018) Christine Calton et al.   Cancers

High plasma levels of soluble programmed cell death ligand 1 are prognostic for reduced survival in advanced lung cancer

(2017) Yusuke Okuma et al.   LUNG CANCER

Sharpening the Edge for Precision Cancer Immunotherapy: Targeting Tumor Antigens through Oncolytic Vaccines

(2017) Namit Holay et al.   Frontiers in Immunology

UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells

(2016) Ismael Samudio et al.   BLOOD

Histone Deacetylase Inhibitors Enhance the Therapeutic Potential of Reovirus in Multiple Myeloma

(2016) A. Stiff et al.   MOLECULAR CANCER THERAPEUTICS

Immunovirotherapy with vesicular stomatitis virus and PD-L1 blockade enhances therapeutic outcome in murine acute myeloid leukemia

(2015) W. Shen et al.   BLOOD

Controlled infection with a therapeutic virus defines the activation kinetics of human natural killer cellsin vivo

(2015) Y. M. El-Sherbiny et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients

(2015) D. M. S. Hossain et al.   CLINICAL CANCER RESEARCH

Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma

(2015) Robert H.I. Andtbacka et al.   JOURNAL OF CLINICAL ONCOLOGY

Decreased expression of pSTAT, IRF-1 and DAP10 signalling molecules in peripheral blood lymphocytes of patients with metastatic melanoma

(2015) Katarina Mirjačić Martinović et al.   JOURNAL OF CLINICAL PATHOLOGY

Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia

(2015) C Parrish et al.   LEUKEMIA

A novel TLR-9 agonist C792 inhibits plasmacytoid dendritic cell-induced myeloma cell growth and enhance cytotoxicity of bortezomib

(2014) A Ray et al.   LEUKEMIA

Lymphokine-activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites

(2013) V.A. Jennings et al.   INTERNATIONAL JOURNAL OF CANCER

NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2

(2013) Todd A Braciak et al.   Journal of Translational Medicine

BCL-2 Inhibitors Sensitize Therapy-resistant Chronic Lymphocytic Leukemia Cells to VSV Oncolysis

(2013) Sara Samuel et al.   MOLECULAR THERAPY

Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy

(2013) Samuel T Workenhe et al.   MOLECULAR THERAPY

Increased PRAME-Specific CTL Killing of Acute Myeloid Leukemia Cells by Either a Novel Histone Deacetylase Inhibitor Chidamide Alone or Combined Treatment with Decitabine

(2013) Yushi Yao et al.   PLoS One

Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway

(2012) Katie Twigger et al.   BMC CANCER

Interferon-Alpha in the Treatment of Multiple Myeloma

(2012) Khoo   CURRENT DRUG TARGETS

Cytotoxic and immune-mediated killing of human colorectal cancer by reovirus-loaded blood and liver mononuclear cells

(2012) Robert A. Adair et al.   INTERNATIONAL JOURNAL OF CANCER

Acute myeloid leukemia targeting by myxoma virus in vivo depends on cell binding but not permissiveness to infection in vitro

(2012) Gerard J. Madlambayan et al.   LEUKEMIA RESEARCH

Interferon-α in acute myeloid leukemia: an old drug revisited

(2011) S Anguille et al.   LEUKEMIA

Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-kappaB mediated and supports innate and adaptive anti-tumour immune priming

(2011) Lynette Steele et al.   Molecular Cancer

Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18

(2011) Gough G Au et al.   Virology Journal

Enhancement of Vaccinia Virus Based Oncolysis with Histone Deacetylase Inhibitors

(2010) Heather MacTavish et al.   PLoS One

Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication

(2009) R. J. Prestwich et al.   CLINICAL CANCER RESEARCH

Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity

(2009) E J Ilett et al.   GENE THERAPY

Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate

(2009) A Poggi et al.   LEUKEMIA

A Phase I Study of Intravenous Oncolytic Reovirus Type 3 Dearing in Patients with Advanced Cancer

(2008) L. Vidal et al.   CLINICAL CANCER RESEARCH

Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

(2008) R. J. Prestwich et al.   CLINICAL CANCER RESEARCH