Increased PRAME-Specific CTL Killing of Acute Myeloid Leukemia Cells by Either a Novel Histone Deacetylase Inhibitor Chidamide Alone or Combined Treatment with Decitabine
出版年份 2013 全文链接
标题
Increased PRAME-Specific CTL Killing of Acute Myeloid Leukemia Cells by Either a Novel Histone Deacetylase Inhibitor Chidamide Alone or Combined Treatment with Decitabine
作者
关键词
Acute myeloid leukemia, Cancer treatment, Cytotoxic T cells, T cells, Cytotoxicity, Bone marrow cells, Leukemia cells, Cell cycle and cell division
出版物
PLoS One
Volume 8, Issue 8, Pages e70522
出版商
Public Library of Science (PLoS)
发表日期
2013-08-06
DOI
10.1371/journal.pone.0070522
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cutting Edge: Chromatin Remodeling as a Molecular Basis for the Enhanced Functionality of Memory CD8 T Cells
- (2014) J. K. Northrop et al. JOURNAL OF IMMUNOLOGY
- CS055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells
- (2012) Ke Gong et al. BIOCHEMICAL JOURNAL
- Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models
- (2012) Li Shen et al. PLoS One
- NYESO-1/LAGE-1s and PRAME Are Targets for Antigen Specific T Cells in Chondrosarcoma following Treatment with 5-Aza-2-Deoxycitabine
- (2012) Seth M. Pollack et al. PLoS One
- Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia
- (2011) Djordje Atanackovic et al. AMERICAN JOURNAL OF HEMATOLOGY
- Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity
- (2011) Zhi-Qiang Ning et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Increased PRAME antigen-specific killing of malignant cell lines by low avidity CTL clones, following treatment with 5-Aza-2′-Deoxycytidine
- (2011) Mengyong Yan et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Improving T-cell Therapy for Relapsed EBV-Negative Hodgkin Lymphoma by Targeting Upregulated MAGE-A4
- (2011) C. R. Cruz et al. CLINICAL CANCER RESEARCH
- Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression
- (2011) Lucas E. Rossi et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo
- (2011) Brian R. Rosborough et al. JOURNAL OF LEUKOCYTE BIOLOGY
- A novel histone deacetylase inhibitor Chidamide induces apoptosis of human colon cancer cells
- (2010) Lin Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia
- (2010) J. Choi et al. BLOOD
- Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia
- (2010) O. Goodyear et al. BLOOD
- Regulation of cancer germline antigen gene expression: implications for cancer immunotherapy
- (2010) Stacey N Akers et al. Future Oncology
- HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells
- (2010) W Song et al. LEUKEMIA
- Functional Anatomy of T Cell Activation and Synapse Formation
- (2009) David R. Fooksman et al. Annual Review of Immunology
- Enhanced Antitumor Activity Induced by Adoptive T-Cell Transfer and Adjunctive Use of the Histone Deacetylase Inhibitor LAQ824
- (2009) D. D. Vo et al. CANCER RESEARCH
- Treatment of Chronic Lymphocytic Leukemia with a Hypomethylating Agent Induces Expression of NXF2, an Immunogenic Cancer Testis Antigen
- (2009) J. A. Dubovsky et al. CLINICAL CANCER RESEARCH
- Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory
- (2009) P. Agarwal et al. JOURNAL OF IMMUNOLOGY
- Aberrant hypomethylation of the cancer–testis antigen PRAME correlates with PRAME expression in acute myeloid leukemia
- (2008) Christina A. Ortmann et al. ANNALS OF HEMATOLOGY
- Epigenetics, DNA Methylation, and Chromatin Modifying Drugs
- (2008) Moshe Szyf Annual Review of Pharmacology and Toxicology
- Ex vivo characterization of polyclonal memory CD8+ T-cell responses to PRAME-specific peptides in patients with acute lymphoblastic leukemia and acute and chronic myeloid leukemia
- (2008) K. Rezvani et al. BLOOD
- Cytotoxic T lymphocytes directed to the preferentially expressed antigen of melanoma (PRAME) target chronic myeloid leukemia
- (2008) C. Quintarelli et al. BLOOD
- The relevance of preferentially expressed antigen of melanoma (PRAME) as a marker of disease activity and prognosis in acute promyelocytic leukemia
- (2008) C. Santamaria et al. HAEMATOLOGICA
- The DNA demethylating agent 5-aza-2′-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma
- (2008) Atsushi Natsume et al. INTERNATIONAL JOURNAL OF CANCER
- Tumor associated antigen PRAME is a marker of favorable prognosis in childhood acute myeloid leukemia patients and modifies the expression of S100A4, Hsp 27, p21, IL-8 and IGFBP-2in vitroandin vivo
- (2008) Nicolas Tajeddine et al. LEUKEMIA & LYMPHOMA
- Liver stroma enhances activation of TLR3-triggered NK cells through fibronectin
- (2008) Sheng Xia et al. MOLECULAR IMMUNOLOGY
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