Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

MicroRNA-199a-5p inhibition enhances the liver repopulation ability of human embryonic stem cell-derived hepatic cells

(2015) Selina Möbus et al.   JOURNAL OF HEPATOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Epigenetics of Reprogramming to Induced Pluripotency

(2013) Bernadett Papp et al.   CELL

Proteome-wide analyses of human hepatocytes during differentiation and dedifferentiation

(2013) Cliff Rowe et al.   HEPATOLOGY

Identification of small molecules for human hepatocyte expansion and iPS differentiation

(2013) Jing Shan et al.   Nature Chemical Biology

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Coordinated elevation of mitochondrial oxidative phosphorylation and autophagy help drive hepatocyte polarization

(2013) D. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies

(2012) J. Fraczek et al.   ARCHIVES OF TOXICOLOGY

Stem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?

(2012) Richard Kia et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Highlights from the International Transporter Consortium Second Workshop

(2012) M J Zamek-Gliszczynski et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Acute Mitochondrial Inhibition by Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase Kinase (MEK) 1/2 Inhibitors Regulates Proliferation

(2012) Maureen O. Ripple et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional 3D Human Primary Hepatocyte Spheroids Made by Co-Culturing Hepatocytes from Partial Hepatectomy Specimens and Human Adipose-Derived Stem Cells

(2012) Da Yoon No et al.   PLoS One

Human liver cell spheroids in extended perfusion bioreactor culture for repeated-dose drug testing

(2011) Rui M. Tostões et al.   HEPATOLOGY

Synergetic effects of DNA demethylation and histone deacetylase inhibition in primary rat hepatocytes

(2011) Joanna Edyta Fraczek et al.   INVESTIGATIONAL NEW DRUGS

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Isolation of Primary Human Hepatocytes from Normal and Diseased Liver Tissue: A One Hundred Liver Experience

(2011) Ricky H. Bhogal et al.   PLoS One

Discovering Networks of Perturbed Biological Processes in Hepatocyte Cultures

(2011) Christopher D. Lasher et al.   PLoS One

Similarities and Differences in the Expression of Drug-Metabolizing Enzymes between Human Hepatic Cell Lines and Primary Human Hepatocytes

(2010) L. Guo et al.   DRUG METABOLISM AND DISPOSITION

Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes

(2010) Sebastian Zellmer et al.   HEPATOLOGY

Network Analysis of Primary Hepatocyte Dedifferentiation Using a Shotgun Proteomics Approach

(2010) Cliff Rowe et al.   JOURNAL OF PROTEOME RESEARCH

A Comparative Study of Genome-Wide Transcriptional Profiles of Primary Hepatocytes in Collagen Sandwich and Monolayer Cultures

(2010) Yeonhee Kim et al.   TISSUE ENGINEERING PART C-METHODS

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor β-induced apoptosis

(2009) Patricio Godoy et al.   HEPATOLOGY

Pharmacogenetic variation at CYP2C9, CYP2C19, and CYP2D6 at global and microgeographic scales

(2009) Johanna Sistonen et al.   Pharmacogenetics and Genomics