Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests

Does Inorganic Mercury Play a Role in Alzheimer's Disease? A Systematic Review and an Integrated Molecular Mechanism

(2017) Joachim Mutter et al.   JOURNAL OF ALZHEIMERS DISEASE

The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy

(2016) Marcel Leist   ALTEX-Alternatives to Animal Experimentation

A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors

(2015) Eugen Rempel et al.   ARCHIVES OF TOXICOLOGY

Developments in our understanding of the genetic basis of birth defects

(2015) Daniel M. Webber et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Association of the NQO1 C609T polymorphism with Alzheimer's disease in Chinese populations: a meta-analysis

(2015) Jingrong Luo et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells

(2015) Patricio Godoy et al.   JOURNAL OF HEPATOLOGY

A novel GBE1 mutation and features of polyglucosan bodies autophagy in Adult Polyglucosan Body Disease

(2015) Simone Sampaolo et al.   NEUROMUSCULAR DISORDERS

Genetic variants in long non-coding RNA MIAT contribute to risk of paranoid schizophrenia in a Chinese Han population

(2015) Shu-Quan Rao et al.   SCHIZOPHRENIA RESEARCH

Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells

(2015) K Meganathan et al.   Cell Death & Disease

Developments in our understanding of the genetic basis of birth defects

(2015) Daniel M. Webber et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

A novel variant inGABRB2associated with intellectual disability and epilepsy

(2014) Siddharth Srivastava et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects

(2014) Nina V. Balmer et al.   ARCHIVES OF TOXICOLOGY

Selenoproteins in Nervous System Development and Function

(2014) Matthew W. Pitts et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

CYP1B1 mutations in patients with primary congenital glaucoma from Saudi Arabia

(2014) Osama M Badeeb et al.   BMC Medical Genetics

CellNet: Network Biology Applied to Stem Cell Engineering

(2014) Patrick Cahan et al.   CELL

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells

(2014) Tanja Waldmann et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Association between ubiquitin carboxy-terminal hydrolase-L1 S18Y variant and risk of Parkinson’s disease: the impact of ethnicity and onset age

(2014) Ying Liu et al.   NEUROLOGICAL SCIENCES

Acrylamide alters neurotransmitter induced calcium responses in murine ESC-derived and primary neurons

(2014) Julia Sisnaiske et al.   NEUROTOXICOLOGY

Lineage-Specific Regulation of Epigenetic Modifier Genes in Human Liver and Brain

(2014) Matthias K. Weng et al.   PLoS One

Test systems of developmental toxicity: state-of-the art and future perspectives

(2013) Marcel Leist et al.   ARCHIVES OF TOXICOLOGY

ARNT2 mutation causes hypopituitarism, post-natal microcephaly, visual and renal anomalies

(2013) Emma A. Webb et al.   BRAIN

Dner inhibits neural progenitor proliferation and induces neuronal and glial differentiation in zebrafish

(2013) Fu-Yu Hsieh et al.   DEVELOPMENTAL BIOLOGY

Post-Approval Safety Issues with Innovative Drugs: A European Cohort Study

(2013) Peter G. M. Mol et al.   DRUG SAFETY

Mercury biomarkers and DNA methylation among michigan dental professionals

(2013) Jaclyn M. Goodrich et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Deficiency of Asparagine Synthetase Causes Congenital Microcephaly and a Progressive Form of Encephalopathy

(2013) Elizabeth K. Ruzzo et al.   NEURON

Maternal Hyperglycemia Activates an ASK1-FoxO3a-Caspase 8 Pathway That Leads to Embryonic Neural Tube Defects

(2013) P. Yang et al.   Science Signaling

Genetic variation in GABRB3 is associated with Asperger syndrome and multiple endophenotypes relevant to autism

(2013) Varun Warrier et al.   Molecular Autism

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

(2012) Anne K. Krug et al.   ARCHIVES OF TOXICOLOGY

PRSS23 is essential for the Snail-dependent endothelial-to-mesenchymal transition during valvulogenesis in zebrafish

(2012) I-Hui Chen et al.   CARDIOVASCULAR RESEARCH

UCHL1 regulates ubiquitination and recycling of the neural cell adhesion molecule NCAM

(2012) Hilke Wobst et al.   FEBS Journal

Identification of Thalidomide-Specific Transcriptomics and Proteomics Signatures during Differentiation of Human Embryonic Stem Cells

(2012) Kesavan Meganathan et al.   PLoS One

Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010

(2011) Sarah Adler et al.   ARCHIVES OF TOXICOLOGY

Increased serum osteopontin levels in autistic children: Relation to the disease severity

(2011) Laila Y. AL-ayadhi et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroprotection by neuropeptide Y in cell and animal models of Parkinson's disease

(2011) Mickael Decressac et al.   NEUROBIOLOGY OF AGING

Assessment of Chemical-Induced Impairment of Human Neurite Outgrowth by Multiparametric Live Cell Imaging in High-Density Cultures

(2011) Nina V. Stiegler et al.   TOXICOLOGICAL SCIENCES

Glutathione enzyme and selenoprotein polymorphisms associate with mercury biomarker levels in Michigan dental professionals

(2011) Jaclyn M. Goodrich et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Defective Mitochondrial mRNA Maturation Is Associated with Spastic Ataxia

(2010) Andrew H. Crosby et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cytosine arabinoside induces ectoderm and inhibits mesoderm expression in human embryonic stem cells during multilineage differentiation

(2010) S Jagtap et al.   BRITISH JOURNAL OF PHARMACOLOGY

Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing

(2010) B Zimmer et al.   CELL DEATH AND DIFFERENTIATION

Thrombospondin 1—a key astrocyte-derived neurogenic factor

(2010) Zhenjie Lu et al.   FASEB JOURNAL

Valproic Acid Monotherapy in Pregnancy and Major Congenital Malformations

(2010) Janneke Jentink et al.   NEW ENGLAND JOURNAL OF MEDICINE

Methylmercury Induces Acute Oxidative Stress, Altering Nrf2 Protein Level in Primary Microglial Cells

(2010) Mingwei Ni et al.   TOXICOLOGICAL SCIENCES

Antioxidative role of selenoprotein W in oxidant-induced mouse embryonic neuronal cell death

(2009) Youn Wook Chung et al.   MOLECULES AND CELLS

A novel ferritin light chain gene mutation in a Japanese family with neuroferritinopathy: Description of clinical features and implications for genotype-phenotype correlations

(2009) Akatsuki Kubota et al.   MOVEMENT DISORDERS

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

(2009) Stuart M Chambers et al.   NATURE BIOTECHNOLOGY

Examination of association of genes in the serotonin system to autism

(2009) B. M. Anderson et al.   NEUROGENETICS

The Cell-Intrinsic Requirement of Sox6 for Cortical Interneuron Development

(2009) Renata Batista-Brito et al.   NEURON

Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration

(2008) Sophia M Blake et al.   EMBO JOURNAL

Effects of UCH-L1 on α-synuclein over-expression mouse model of Parkinson’s disease

(2008) Toru Yasuda et al.   JOURNAL OF NEUROCHEMISTRY