Maternal Hyperglycemia Activates an ASK1-FoxO3a-Caspase 8 Pathway That Leads to Embryonic Neural Tube Defects

Oxidative Stress-Induced JNK1/2 Activation Triggers Proapoptotic Signaling and Apoptosis That Leads to Diabetic Embryopathy

(2012) X. Li et al.   DIABETES

c-Jun NH2-Terminal Kinase 1/2 and Endoplasmic Reticulum Stress as Interdependent and Reciprocal Causation in Diabetic Embryopathy

(2012) X. Li et al.   DIABETES

SOD1 overexpression in vivo blocks hyperglycemia-induced specific PKC isoforms: substrate activation and consequent lipid peroxidation in diabetic embryopathy

(2011) Xuezheng Li et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Altered gene expression and spongiotrophoblast differentiation in placenta from a mouse model of diabetes in pregnancy

(2011) J. M. Salbaum et al.   DIABETOLOGIA

Valproic Acid Increases Formation of Reactive Oxygen Species and Induces Apoptosis in Postimplantation Embryos: A Role for Oxidative Stress in Valproic Acid-Induced Neural Tube Defects

(2011) E. W. Y. Tung et al.   MOLECULAR PHARMACOLOGY

Neural tube defect genes and maternal diabetes during pregnancy

(2010) J. Michael Salbaum et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

(2010) Muriel J. Harris et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Transgenic mice overproducing human thioredoxin-1, an antioxidative and anti-apoptotic protein, prevents diabetic embryopathy

(2010) Y. Kamimoto et al.   DIABETOLOGIA

Caspase-8: a key role in the pathogenesis of diabetic embryopathy

(2009) Zhiyong Zhao et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Prevention of neural tube defects by loss of function of inducible nitric oxide synthase in fetuses of a mouse model of streptozotocin-induced diabetes

(2009) Y. Sugimura et al.   DIABETOLOGIA

Apoptosis is not required for mammalian neural tube closure

(2009) V. Massa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of oxidative stress signaling that is implicated in apoptosis with a mouse model of diabetic embryopathy

(2008) Peixin Yang et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Thioredoxin-1 Ameliorates Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

(2008) A. Sato et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS