Systematic Review on the Involvement of the Kynurenine Pathway in Stroke: Pre-clinical and Clinical Evidence

Age and sex differences in the pathophysiology of acute CNS injury

(2019) TaeHee Kim et al.   NEUROCHEMISTRY INTERNATIONAL

Immune Cells After Ischemic Stroke Onset: Roles, Migration, and Target Intervention

(2018) Lu-yao Ao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Gemst: a taylor-made combination that reverts neuroanatomical changes in stroke

(2017) Arturo Mangas et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Stroke

(2017) Graeme J Hankey   LANCET

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

(2017) Qiao Huang et al.   MOLECULAR NEUROBIOLOGY

The Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia

(2016) María Isabel Cuartero et al.   CURRENT PHARMACEUTICAL DESIGN

Targeting of the kynurenic acid across the blood–brain barrier by core-shell nanoparticles

(2016) N. Varga et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Ischemic preconditioning protects neurons from damage and maintains the immunoreactivity of kynurenic acid in the gerbil hippocampal CA1 region following transient cerebral ischemia

(2015) JAE-CHUL LEE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Targeting brain microvascular endothelial cells: a therapeutic approach to neuroprotection against stroke

(2015) Qi-jin Yu et al.   Neural Regeneration Research

NAMPT as a Therapeutic Target against Stroke

(2015) Pei Wang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Kynurenine 3-Monooxygenase: An Influential Mediator of Neuropathology

(2015) Jennifer M. Parrott et al.   Frontiers in Psychiatry

SYRCLE’s risk of bias tool for animal studies

(2014) Carlijn R Hooijmans et al.   BMC Medical Research Methodology

L-Kynurenine/Aryl Hydrocarbon Receptor Pathway Mediates Brain Damage After Experimental Stroke

(2014) María I. Cuartero et al.   CIRCULATION

Activation of the Kynurenine Pathway in the Acute Phase of Stroke and its Role in Fatigue and Depression Following Stroke

(2014) Heidi Ormstad et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Serum indoleamine 2,3-dioxygenase and kynurenine aminotransferase enzyme activity in patients with ischemic stroke

(2013) Ximing Mo et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Post-ischemic treatment with L-kynurenine sulfate exacerbates neuronal damage after transient middle cerebral artery occlusion

(2013) L. Gellért et al.   NEUROSCIENCE

Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: Facts and challenges

(2012) Edson X. Albuquerque et al.   BIOCHEMICAL PHARMACOLOGY

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Kynurenic acid attenuates multiorgan dysfunction in rats after heatstroke

(2011) Yi-chang Hsieh et al.   ACTA PHARMACOLOGICA SINICA

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

(2011) Daniel Zwilling et al.   CELL

Neuroprotection with a new kynurenic acid analog in the four-vessel occlusion model of ischemia

(2011) Levente Gellért et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The kynurenine system and immunoregulation

(2011) Yvette Mándi et al.   JOURNAL OF NEURAL TRANSMISSION

The relationship between indoleamine 2,3-dioxygenase activity and post-stroke cognitive impairment

(2011) Allison B Gold et al.   Journal of Neuroinflammation

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?

(2011) Johann Steiner et al.   Journal of Neuroinflammation

Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia–reperfusion in mice

(2011) Katherine A. Jackman et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Role of Tryptophan Catabolism along the Kynurenine Pathway in Acute Ischemic Stroke

(2010) Raf Brouns et al.   NEUROCHEMICAL RESEARCH

Identification and characterization of novel variants of the tryptophan 2,3-dioxygenase gene: Differential regulation in the mouse nervous system during development

(2009) Masaaki Kanai et al.   NEUROSCIENCE RESEARCH

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

Neuroprotection achieved in the ischaemic rat cortex with l-kynurenine sulphate

(2008) Hermina Robotka et al.   LIFE SCIENCES

Kynurenine diminishes the ischemia-induced histological and electrophysiological deficits in the rat hippocampus

(2008) Katalin Sas et al.   NEUROBIOLOGY OF DISEASE

Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-γ-independent pathway following transient global ischemia in mouse

(2008) Masato Hoshi et al.   NEUROSCIENCE RESEARCH

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING