The Modulation of Regulatory T Cells via HMGB1/PTEN/β-Catenin Axis in LPS Induced Acute Lung Injury

Acute Respiratory Distress Syndrome

(2018) Eddy Fan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Phosphatase and tensin homolog-β-catenin signaling modulates regulatory T cells and inflammatory responses in mouse liver ischemia/reperfusion injury

(2017) Qiang Zhu et al.   LIVER TRANSPLANTATION

PTEN–Foxo1 signaling triggers HMGB1-mediated innate immune responses in acute lung injury

(2015) Min Zhou et al.   IMMUNOLOGIC RESEARCH

T-Regulatory Cells and Programmed Death 1+T Cells Contribute to Effector T-Cell Dysfunction in Patients with Chronic Obstructive Pulmonary Disease

(2014) Suresh Gopi Kalathil et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

β-Catenin–regulated myeloid cell adhesion and migration determine wound healing

(2014) Saeid Amini-Nik et al.   JOURNAL OF CLINICAL INVESTIGATION

Myeloid PTEN Deficiency Protects Livers from Ischemia Reperfusion Injury by Facilitating M2 Macrophage Differentiation

(2014) S. Yue et al.   JOURNAL OF IMMUNOLOGY

Alveolar macrophage phagocytic activity is enhanced with LPS priming, and combined stimulation of LPS and lipoteichoic acid synergistically induce pro-inflammatory cytokines in pigs

(2013) Mohammad Ariful Islam et al.   Innate Immunity

Lung-resident tissue macrophages generate Foxp3+regulatory T cells and promote airway tolerance

(2013) Pejman Soroosh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

BLT1-dependent Alveolar Recruitment of CD4+CD25+Foxp3+Regulatory T Cells Is Important for Resolution of Acute Lung Injury

(2012) Luman Wang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulatory T Cells Reduce Acute Lung Injury Fibroproliferation by Decreasing Fibrocyte Recruitment

(2012) Brian T. Garibaldi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

PTEN-mediated akt/β-Catenin/foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury

(2012) Naoko Kamo et al.   HEPATOLOGY

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock

(2012) Ezra Aksoy et al.   NATURE IMMUNOLOGY

High-mobility group box family of proteins: ligand and sensor for innate immunity

(2012) Hideyuki Yanai et al.   TRENDS IN IMMUNOLOGY

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Knockdown of HMGB1 in Tumor Cells Attenuates Their Ability To Induce Regulatory T Cells and Uncovers Naturally Acquired CD8 T Cell-Dependent Antitumor Immunity

(2011) Z. Liu et al.   JOURNAL OF IMMUNOLOGY

Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development

(2010) Weiming Ouyang et al.   IMMUNITY

T Regulatory Cells Maintain Intestinal Homeostasis by Suppressing γδ T Cells

(2010) Sung-Gyoo Park et al.   IMMUNITY

Myeloid PTEN Promotes Inflammation but Impairs Bactericidal Activities during Murine Pneumococcal Pneumonia

(2010) G. Schabbauer et al.   JOURNAL OF IMMUNOLOGY

Phosphoinositide-Dependent Kinase 1 Provides Negative Feedback Inhibition to Toll-Like Receptor-Mediated NF- B Activation in Macrophages

(2010) B. Chaurasia et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of  -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

(2010) S. Manicassamy et al.   SCIENCE

CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury

(2009) Franco R. D’Alessio et al.   JOURNAL OF CLINICAL INVESTIGATION

Protein Kinase B/Akt Signals Impair Th17 Differentiation and Support Natural Regulatory T Cell Function and Induced Regulatory T Cell Formation

(2009) M. Pierau et al.   JOURNAL OF IMMUNOLOGY

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

Extracellular High-Mobility Group Box 1 Acts as an Innate Immune Mediator to Enhance Autoimmune Progression and Diabetes Onset in NOD Mice

(2008) J. Han et al.   DIABETES

TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function

(2008) Liang Zhou et al.   NATURE

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

(2008) Yi Ding et al.   NATURE MEDICINE

Protective Effect of Antagonist of High-mobility Group Box 1 on Lipopolysaccharide-Induced Acute Lung Injury in Mice

(2008) Q. Gong et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY