标题
ADAR1: “Editor-in-Chief” of Cytoplasmic Innate Immunity
作者
关键词
-
出版物
Frontiers in Immunology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-07-25
DOI
10.3389/fimmu.2019.01763
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- ADAR1: A New Target for Immuno-oncology Therapy
- (2019) Amruta Bhate et al. MOLECULAR CELL
- Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA–triggered innate immune responses
- (2019) Charles E. Samuel JOURNAL OF BIOLOGICAL CHEMISTRY
- Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
- (2018) Hachung Chung et al. CELL
- Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation
- (2018) Sadeem Ahmad et al. CELL
- ADARs and editing: The role of A-to-I RNA modification in cancer progression
- (2018) Kajsa Fritzell et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Mitochondrial double-stranded RNA triggers antiviral signalling in humans
- (2018) Ashish Dhir et al. NATURE
- Defects in interferon pathways as potential biomarkers of sensitivity to oncolytic viruses
- (2018) Olga V. Matveeva et al. REVIEWS IN MEDICAL VIROLOGY
- Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
- (2018) Jeffrey J. Ishizuka et al. NATURE
- Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss
- (2018) Huayang Liu et al. NATURE MEDICINE
- Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells
- (2018) Hugh S. Gannon et al. Nature Communications
- Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers
- (2017) Yumeng Wang et al. GENOME RESEARCH
- Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line
- (2017) Yize Li et al. eLife
- RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages
- (2017) Maria Pujantell et al. Scientific Reports
- P53 and the defenses against genome instability caused by transposons and repetitive elements
- (2016) Arnold J. Levine et al. BIOESSAYS
- ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis
- (2016) Maria Anna Zipeto et al. Cell Stem Cell
- Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon
- (2016) Lemin Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PKR Transduces MDA5-Dependent Signals for Type I IFN Induction
- (2016) Alissa M. Pham et al. PLoS Pathogens
- ADAR1 Suppresses the Activation of Cytosolic RNA-Sensing Signaling Pathways to Protect the Liver from Ischemia/Reperfusion Injury
- (2016) Hui Wang et al. Scientific Reports
- Characterization of human disease phenotypes associated with mutations inTREX1,RNASEH2A,RNASEH2B,RNASEH2C,SAMHD1,ADAR, andIFIH1
- (2015) Yanick J. Crow et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- DNA and RNA editing of retrotransposons accelerate mammalian genome evolution
- (2015) Binyamin A. Knisbacher et al. Annals of the New York Academy of Sciences
- The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers
- (2015) Leng Han et al. CANCER CELL
- RNA over-editing of BLCAP contributes to hepatocarcinogenesis identified by whole-genome and transcriptome sequencing
- (2015) Xueda Hu et al. CANCER LETTERS
- p53 genes function to restrain mobile elements
- (2015) Annika Wylie et al. GENES & DEVELOPMENT
- Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
- (2015) Kathleen Pestal et al. IMMUNITY
- RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
- (2015) B. J. Liddicoat et al. SCIENCE
- Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors
- (2015) Nurit Paz-Yaacov et al. Cell Reports
- Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome
- (2015) Debora Fumagalli et al. Cell Reports
- ADAR1, inosine and the immune sensing system: distinguishing self from non-self
- (2015) Brian J. Liddicoat et al. Wiley Interdisciplinary Reviews-RNA
- Aicardi-Goutières Syndrome Is Caused by IFIH1 Mutations
- (2014) Hirotsugu Oda et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Excessive production and extreme editing of human metapneumovirus defective interfering RNA is associated with type I IFN induction
- (2014) B. G. van den Hoogen et al. JOURNAL OF GENERAL VIROLOGY
- Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs
- (2014) Shengyong Yang et al. JOURNAL OF IMMUNOLOGY
- Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
- (2014) Gillian I Rice et al. NATURE GENETICS
- A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1
- (2014) P. Barraud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1
- (2014) Lijo John et al. VIROLOGY
- A genome-wide map of hyper-edited RNA reveals numerous new sites
- (2014) Hagit T. Porath et al. Nature Communications
- The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
- (2014) Niamh M. Mannion et al. Cell Reports
- Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response
- (2014) Niyas Kudukkil Pulloor et al. PLoS Pathogens
- Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
- (2013) Y.-R. Qin et al. CANCER RESEARCH
- ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing
- (2013) Hiromitsu Ota et al. CELL
- A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes
- (2013) L. Bazak et al. GENOME RESEARCH
- Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses
- (2013) C. S. Ng et al. JOURNAL OF VIROLOGY
- Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study
- (2013) Gillian I Rice et al. LANCET NEUROLOGY
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
- (2013) Leilei Chen et al. NATURE MEDICINE
- Identifying RNA editing sites using RNA sequencing data alone
- (2013) Gokul Ramaswami et al. NATURE METHODS
- The Interactomes of Influenza Virus NS1 and NS2 Proteins Identify New Host Factors and Provide Insights for ADAR1 Playing a Supportive Role in Virus Replication
- (2013) Benoît de Chassey et al. PLoS Pathogens
- RNase L Induces Autophagy via c-Jun N-terminal Kinase and Double-stranded RNA-dependent Protein Kinase Signaling Pathways
- (2012) Mohammad Adnan Siddiqui et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RNase L Triggers Autophagy in Response to Viral Infections
- (2012) A. Chakrabarti et al. JOURNAL OF VIROLOGY
- Stress Granule Formation Induced by Measles Virus Is Protein Kinase PKR Dependent and Impaired by RNA Adenosine Deaminase ADAR1
- (2012) K. M. Okonski et al. JOURNAL OF VIROLOGY
- Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome
- (2012) Zhiyu Peng et al. NATURE BIOTECHNOLOGY
- Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature
- (2012) Gillian I Rice et al. NATURE GENETICS
- Accurate identification of human Alu and non-Alu RNA editing sites
- (2012) Gokul Ramaswami et al. NATURE METHODS
- Heterochromatin instability in cancer: From the Barr body to satellites and the nuclear periphery
- (2012) Dawn M. Carone et al. SEMINARS IN CANCER BIOLOGY
- Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response
- (2011) Christian K Pfaller et al. CURRENT OPINION IN IMMUNOLOGY
- Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral
- (2011) Charles E. Samuel VIROLOGY
- Site-selective versus promiscuous A-to-I editing
- (2011) Helene Wahlstedt et al. Wiley Interdisciplinary Reviews-RNA
- Functions and Regulation of RNA Editing by ADAR Deaminases
- (2010) Kazuko Nishikura Annual Review of Biochemistry
- Pattern Recognition Receptors and Inflammation
- (2010) Osamu Takeuchi et al. CELL
- Protein Kinase R Contributes to Immunity against Specific Viruses by Regulating Interferon mRNA Integrity
- (2010) Oliver Schulz et al. Cell Host & Microbe
- Adenosine Deaminases Acting on RNA, RNA Editing, and Interferon Action
- (2010) Cyril X. George et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Inosine cyanoethylation identifies A-to-I RNA editing sites in the human transcriptome
- (2010) Masayuki Sakurai et al. Nature Chemical Biology
- Double-stranded RNAs containing multiple IU pairs are sufficient to suppress interferon induction and apoptosis
- (2010) Patrice Vitali et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR
- (2009) Ann M. Toth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response
- (2009) G. Barry et al. JOURNAL OF GENERAL VIROLOGY
- Adenosine Deaminase ADAR1 Increases Gene Expression at the Translational Level by Decreasing Protein Kinase PKR-Dependent eIF-2α Phosphorylation
- (2009) Ying Wang et al. JOURNAL OF MOLECULAR BIOLOGY
- Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus
- (2009) C. S. McAllister et al. JOURNAL OF VIROLOGY
- ADAR1 Interacts with PKR during Human Immunodeficiency Virus Infection of Lymphocytes and Contributes to Viral Replication
- (2009) G. Clerzius et al. JOURNAL OF VIROLOGY
- Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection
- (2009) Margherita Doria et al. NUCLEIC ACIDS RESEARCH
- Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing
- (2009) J. B. Li et al. SCIENCE
- RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment
- (2009) Zhiqun Li et al. VIROLOGY
- Activation of the Antiviral Kinase PKR and Viral Countermeasures
- (2009) Bianca Dauber et al. Viruses-Basel
- The RNA-activated Protein Kinase Enhances the Induction of Interferon-β and Apoptosis Mediated by Cytoplasmic RNA Sensors
- (2008) Christopher S. McAllister et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Double-Stranded RNA Adenosine Deaminases Enhance Expression of Human Immunodeficiency Virus Type 1 Proteins
- (2008) A. Phuphuakrat et al. JOURNAL OF VIROLOGY
- ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
- (2008) Jochen C Hartner et al. NATURE IMMUNOLOGY
- Frequency and fate of microRNA editing in human brain
- (2008) Y. Kawahara et al. NUCLEIC ACIDS RESEARCH
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