标题
Targeting the Complement Pathway as a Therapeutic Strategy in Lung Cancer
作者
关键词
-
出版物
Frontiers in Immunology
Volume 10, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-05-10
DOI
10.3389/fimmu.2019.00954
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Comparing and contrasting predictive biomarkers for immunotherapy and targeted therapy of NSCLC
- (2019) D. Ross Camidge et al. Nature Reviews Clinical Oncology
- Nivolumab Plus Erlotinib in Patients With EGFR -Mutant Advanced NSCLC
- (2018) Scott Gettinger et al. Journal of Thoracic Oncology
- Osimertinib in Untreated EGFR-Mutated Advanced Non–Small-Cell Lung Cancer
- (2018) Jean-Charles Soria et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting complement-mediated immunoregulation for cancer immunotherapy
- (2018) Martin Kolev et al. SEMINARS IN IMMUNOLOGY
- Pembrolizumab plus Chemotherapy for Squamous Non–Small-Cell Lung Cancer
- (2018) Luis Paz-Ares et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting oncogenic drivers in lung cancer: Recent progress, current challenges and future opportunities
- (2018) Satoshi Yoda et al. PHARMACOLOGY & THERAPEUTICS
- Aurora kinase A drives the evolution of resistance to third-generation EGFR inhibitors in lung cancer
- (2018) Khyati N. Shah et al. NATURE MEDICINE
- A systematic review of the validity of patient derived xenograft (PDX) models: the implications for translational research and personalised medicine
- (2018) Anne T. Collins et al. PeerJ
- The complement system in cancer: Ambivalence between tumour destruction and promotion
- (2017) Srinivas Mamidi et al. IMMUNOBIOLOGY
- The role of the complement system in cancer
- (2017) Vahid Afshar-Kharghan JOURNAL OF CLINICAL INVESTIGATION
- Intracellular complement − the complosome − in immune cell regulation
- (2017) Giuseppina Arbore et al. MOLECULAR IMMUNOLOGY
- The renaissance of complement therapeutics
- (2017) Daniel Ricklin et al. Nature Reviews Nephrology
- Complement anaphylatoxins C3a and C5a: Emerging roles in cancer progression and treatment
- (2017) Daniel Ajona et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Targeting the PD-1/PD-L1 Immune Checkpoint in EGFR-Mutated or ALK-Translocated Non-Small-Cell Lung Cancer
- (2017) Olivier Bylicki et al. Targeted Oncology
- A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis
- (2017) Daniel Ajona et al. Cancer Discovery
- Complement C4d-specific antibodies for the diagnosis of lung cancer
- (2017) Daniel Ajona et al. Oncotarget
- Kras and Tumor Immunity: Friend or Foe?
- (2017) Jane Cullis et al. Cold Spring Harbor Perspectives in Medicine
- The Tumor Microenvironment Regulates Sensitivity of Murine Lung Tumors to PD-1/PD-L1 Antibody Blockade
- (2017) Howard Y. Li et al. Cancer Immunology Research
- Blocking C5aR signaling promotes the anti-tumor efficacy of PD-1/PD-L1 blockade
- (2017) Haoran Zha et al. OncoImmunology
- Local endothelial complement activation reverses endothelial quiescence, enabling t-cell homing, and tumor control during t-cell immunotherapy
- (2017) Andrea Facciabene et al. OncoImmunology
- Paroxysmal nocturnal haemoglobinuria
- (2017) Anita Hill et al. Nature Reviews Disease Primers
- Cancer statistics, 2016
- (2016) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Innate immune signaling and regulation in cancer immunotherapy
- (2016) Leticia Corrales et al. CELL RESEARCH
- Third-generation inhibitors targeting EGFR T790M mutation in advanced non-small cell lung cancer
- (2016) Shuhang Wang et al. Journal of Hematology & Oncology
- The Complement C3a Receptor Contributes to Melanoma Tumorigenesis by Inhibiting Neutrophil and CD4+T Cell Responses
- (2016) Jamileh A. Nabizadeh et al. JOURNAL OF IMMUNOLOGY
- K-Ras protein as a drug target
- (2016) Frank McCormick JOURNAL OF MOLECULAR MEDICINE-JMM
- Targeting the complement cascade: novel treatments coming down the pike
- (2016) Joshua M. Thurman et al. KIDNEY INTERNATIONAL
- Activity and safety of ceritinib in patients with ALK -rearranged non-small-cell lung cancer (ASCEND-1): updated results from the multicentre, open-label, phase 1 trial
- (2016) Dong-Wan Kim et al. LANCET ONCOLOGY
- Mutational landscape ofEGFR-,MYC-, andKras-driven genetically engineered mouse models of lung adenocarcinoma
- (2016) David G. McFadden et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
- (2016) G. Arbore et al. SCIENCE
- Testing for ROS1 in non-small cell lung cancer: a review with recommendations
- (2016) Lukas Bubendorf et al. VIRCHOWS ARCHIV
- The Non–Small Cell Lung Cancer Immune Contexture. A Major Determinant of Tumor Characteristics and Patient Outcome
- (2015) Romain Remark et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
- (2015) Suzanne L. Topalian et al. CANCER CELL
- PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer
- (2015) Eduardo Bonavita et al. CELL
- Immune Checkpoint Modulation for Non-Small Cell Lung Cancer
- (2015) J.-C. Soria et al. CLINICAL CANCER RESEARCH
- EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors
- (2015) D. Ercan et al. CLINICAL CANCER RESEARCH
- Squamous Cell Lung Cancer: From Tumor Genomics to Cancer Therapeutics
- (2015) D. R. Gandara et al. CLINICAL CANCER RESEARCH
- Immune Checkpoint Blockade in Cancer Therapy
- (2015) Michael A. Postow et al. JOURNAL OF CLINICAL ONCOLOGY
- Complement Component 3 Is Regulated by TWIST1 and Mediates Epithelial–Mesenchymal Transition
- (2015) Min Soon Cho et al. JOURNAL OF IMMUNOLOGY
- Deletion of 5-Lipoxygenase in the Tumor Microenvironment Promotes Lung Cancer Progression and Metastasis through Regulating T Cell Recruitment
- (2015) Joanna M. Poczobutt et al. JOURNAL OF IMMUNOLOGY
- Pulmonary Alveolar Macrophages Contribute to the Premetastatic Niche by Suppressing Antitumor T Cell Responses in the Lungs
- (2015) Sharad K. Sharma et al. JOURNAL OF IMMUNOLOGY
- Molecularly Targeted Therapies in Non–Small-Cell Lung Cancer Annual Update 2014
- (2015) Daniel Morgensztern et al. Journal of Thoracic Oncology
- IgM exacerbates glomerular disease progression in complement-induced glomerulopathy
- (2015) Sarah E. Panzer et al. KIDNEY INTERNATIONAL
- EGFR tyrosine kinase inhibitors in squamous cell lung cancer
- (2015) Fred R Hirsch et al. LANCET ONCOLOGY
- Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer
- (2015) Edward B. Garon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Natural and adaptive IgM antibodies in the recognition of tumor-associated antigens of breast cancer (Review)
- (2015) MARIANA DÍAZ-ZARAGOZA et al. ONCOLOGY REPORTS
- Complement factor H polymorphism rs1061170 and the effect of cigarette smoking on the risk of lung cancer
- (2015) Nada Ezzeldin et al. Wspolczesna Onkologia-Contemporary Oncology
- Complement System Part II: Role in Immunity
- (2015) Nicolas S. Merle et al. Frontiers in Immunology
- Complement System Part I – Molecular Mechanisms of Activation and Regulation
- (2015) Nicolas S. Merle et al. Frontiers in Immunology
- Development of PD-1/PD-L1 Pathway in Tumor Immune Microenvironment and Treatment for Non-Small Cell Lung Cancer
- (2015) Jiabei He et al. Scientific Reports
- Peroxisome Proliferator-Activated Receptor-γ Inhibits Transformed Growth of Non-Small Cell Lung Cancer Cells through Selective Suppression of Snail
- (2015) Rashmi Choudhary et al. NEOPLASIA
- Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche
- (2014) S. K. Vadrevu et al. CANCER RESEARCH
- Natural IgM: Beneficial Autoantibodies for the Control of Inflammatory and Autoimmune Disease
- (2014) Caroline Grönwall et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Immunotherapy in the treatment of non-small cell lung cancer
- (2014) Raghav Sundar et al. LUNG CANCER
- Complement component 3 is a prognostic factor of non-small cell lung cancer
- (2014) KAILONG LIN et al. Molecular Medicine Reports
- In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system
- (2014) Danilo Maddalo et al. NATURE
- Multiple cells-of-origin of mutant K-Ras–induced mouse lung adenocarcinoma
- (2014) Kate D. Sutherland et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autocrine Effects of Tumor-Derived Complement
- (2014) Min Soon Cho et al. Cell Reports
- Enhancement of Human Cancer Cell Motility and Invasiveness by Anaphylatoxin C5a via Aberrantly Expressed C5a Receptor (CD88)
- (2013) H. Nitta et al. CLINICAL CANCER RESEARCH
- Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment
- (2013) Thomas F Gajewski et al. CURRENT OPINION IN IMMUNOLOGY
- Targeting the RAS oncogene
- (2013) Asami Takashima et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Intracellular Complement Activation Sustains T Cell Homeostasis and Mediates Effector Differentiation
- (2013) M. Kathryn Liszewski et al. IMMUNITY
- Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells
- (2013) Wing-hong Kwan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- At the Bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy
- (2013) Andrew M. Intlekofer et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Investigation of Complement Activation Product C4d as a Diagnostic and Prognostic Biomarker for Lung Cancer
- (2013) Daniel Ajona et al. JNCI-Journal of the National Cancer Institute
- Overexpression of CD88 predicts poor prognosis in non-small-cell lung cancer
- (2013) Jie Gu et al. LUNG CANCER
- Novel roles for complement receptors in T cell regulation and beyond
- (2013) Claudia Kemper et al. MOLECULAR IMMUNOLOGY
- Mouse models for lung cancer
- (2013) Min-chul Kwon et al. Molecular Oncology
- Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer
- (2013) Aria Vaishnavi et al. NATURE MEDICINE
- Novel Targets in Non-Small Cell Lung Cancer: ROS1 and RET Fusions
- (2013) J. F. Gainor et al. ONCOLOGIST
- Eicosanoid Profiling in an Orthotopic Model of Lung Cancer Progression by Mass Spectrometry Demonstrates Selective Production of Leukotrienes by Inflammatory Cells of the Microenvironment
- (2013) Joanna M. Poczobutt et al. PLoS One
- Complement inhibition in cancer therapy
- (2013) Ruben Pio et al. SEMINARS IN IMMUNOLOGY
- Early onset and enhanced growth of autochthonous mammary carcinomas in C3-deficient Her2/neu transgenic mice
- (2013) Silvio Bandini et al. OncoImmunology
- Engineering humanized mice for improved hematopoietic reconstitution
- (2012) Adam C Drake et al. Cellular & Molecular Immunology
- Squamous Cell Carcinoma of the Lung: Molecular Subtypes and Therapeutic Opportunities
- (2012) P. Perez-Moreno et al. CLINICAL CANCER RESEARCH
- Lung cancer chemoprevention: difficulties, promise and potential agents?
- (2012) Konstantine Dragnev et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Regulation of Humoral Immunity by Complement
- (2012) Michael C. Carroll et al. IMMUNITY
- Anaphylatoxin C5a Creates a Favorable Microenvironment for Lung Cancer Progression
- (2012) Leticia Corrales et al. JOURNAL OF IMMUNOLOGY
- Opposing Roles for Complement Component C5a in Tumor Progression and the Tumor Microenvironment
- (2012) L. Gunn et al. JOURNAL OF IMMUNOLOGY
- Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study
- (2012) D Ross Camidge et al. LANCET ONCOLOGY
- Absence of signaling into CD4+ cells via C3aR and C5aR enables autoinductive TGF-β1 signaling and induction of Foxp3+ regulatory T cells
- (2012) Michael G Strainic et al. NATURE IMMUNOLOGY
- Oral Iloprost Improves Endobronchial Dysplasia in Former Smokers
- (2011) R. L. Keith et al. Cancer Prevention Research
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Chronic inflammation, the tumor microenvironment and carcinogenesis
- (2011) Tamas A. Gonda et al. CELL CYCLE
- Novel roles of complement in T effector cell regulation
- (2011) Peter S. Heeger et al. IMMUNOBIOLOGY
- Activation of PPARγ in Myeloid Cells Promotes Lung Cancer Progression and Metastasis
- (2011) Howard Li et al. PLoS One
- Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion
- (2011) R. D. Schreiber et al. SCIENCE
- Complement: a key system for immune surveillance and homeostasis
- (2010) Daniel Ricklin et al. NATURE IMMUNOLOGY
- EML4-ALK Mutations in Lung Cancer That Confer Resistance to ALK Inhibitors
- (2010) Young Lim Choi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer
- (2010) Eunice L. Kwak et al. NEW ENGLAND JOURNAL OF MEDICINE
- Depletion of Cytosolic Phospholipase A2 in Bone Marrow-Derived Macrophages Protects against Lung Cancer Progression and Metastasis
- (2009) M. C.M. Weiser-Evans et al. CANCER RESEARCH
- KIF5B-ALK, a Novel Fusion Oncokinase Identified by an Immunohistochemistry-based Diagnostic System for ALK-positive Lung Cancer
- (2009) K. Takeuchi et al. CLINICAL CANCER RESEARCH
- Neutralization of complement regulatory proteins CD55 and CD59 augments therapeutic effect of herceptin against lung carcinoma cells
- (2009) Chen ONCOLOGY REPORTS
- Modulation of Protective T Cell Immunity by Complement Inhibitor Expression on Tumor Cells
- (2008) J. C. Varela et al. CANCER RESEARCH
- EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer
- (2008) J. P. Koivunen et al. CLINICAL CANCER RESEARCH
- Lung adenocarcinoma: guiding EGFR-targeted therapy and beyond
- (2008) Marc Ladanyi et al. MODERN PATHOLOGY
- Modulation of the antitumor immune response by complement
- (2008) Maciej M Markiewski et al. NATURE IMMUNOLOGY
- The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
- (2008) C.-H. Yun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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