The Complement C3a Receptor Contributes to Melanoma Tumorigenesis by Inhibiting Neutrophil and CD4+T Cell Responses

Complement Inhibition: A Novel Form of Immunotherapy for Colon Cancer

(2015) Stephanie Downs-Canner et al.   ANNALS OF SURGICAL ONCOLOGY

PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer

(2015) Eduardo Bonavita et al.   CELL

Complement Is a Central Mediator of Radiotherapy-Induced Tumor-Specific Immunity and Clinical Response

(2015) Laura Surace et al.   IMMUNITY

Complement Component 3 Is Regulated by TWIST1 and Mediates Epithelial–Mesenchymal Transition

(2015) Min Soon Cho et al.   JOURNAL OF IMMUNOLOGY

Is the Complement Activation Product C3a a Proinflammatory Molecule? Re-evaluating the Evidence and the Myth

(2015) Liam G. Coulthard et al.   JOURNAL OF IMMUNOLOGY

Genetic and Pharmacologic Inhibition of Complement Impairs Endothelial Cell Function and Ablates Ovarian Cancer Neovascularization

(2015) Selene Nunez-Cruz et al.   NEOPLASIA

Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer

(2014) Evgeniy B. Eruslanov et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 T-cell Subsets and Tumor Immunity: The Helpful and the Not-so-Helpful

(2014) H.-J. Kim et al.   Cancer Immunology Research

Myeloid-derived cells are key targets of tumor immunotherapy

(2014) José Medina-Echeverz et al.   OncoImmunology

Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression

(2013) Inbal Mishalian et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Host immunity contributes to the anti-melanoma activity of BRAF inhibitors

(2013) Deborah A. Knight et al.   JOURNAL OF CLINICAL INVESTIGATION

Investigation of Complement Activation Product C4d as a Diagnostic and Prognostic Biomarker for Lung Cancer

(2013) Daniel Ajona et al.   JNCI-Journal of the National Cancer Institute

Cutaneous melanoma

(2013) Alexander MM Eggermont et al.   LANCET

The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization

(2013) Mike C. L. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role and Regulation of Human Th17 Cells in Tumor Immunity

(2012) Jian Ye et al.   AMERICAN JOURNAL OF PATHOLOGY

Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling

(2012) S. Bugl et al.   BLOOD

Anti-cancer versus cancer-promoting effects of the interleukin-17-producing T helper cells

(2012) Nasr Y.A. Hemdan   IMMUNOLOGY LETTERS

Anaphylatoxin C5a Creates a Favorable Microenvironment for Lung Cancer Progression

(2012) Leticia Corrales et al.   JOURNAL OF IMMUNOLOGY

Opposing Roles for Complement Component C5a in Tumor Progression and the Tumor Microenvironment

(2012) L. Gunn et al.   JOURNAL OF IMMUNOLOGY

Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils

(2012) Zvi G. Fridlender et al.   PLoS One

Negative Regulation of Pulmonary Th17 Responses by C3a Anaphylatoxin during Allergic Inflammation in Mice

(2012) Hoyong Lim et al.   PLoS One

Serum Proteomic Profiling Reveals That Pretreatment Complement Protein Levels are Predictive of Esophageal Cancer Patient Response to Neoadjuvant Chemoradiation

(2011) Stephen G. Maher et al.   ANNALS OF SURGERY

Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung

(2011) Zvi Granot et al.   CANCER CELL

Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control

(2011) M. Hong et al.   CANCER RESEARCH

Tumor-Associated Neutrophils: New Targets for Cancer Therapy

(2011) A. D. Gregory et al.   CANCER RESEARCH

On the dual roles and polarized phenotypes of neutrophils in tumor development and progression

(2011) H. Piccard et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Successful Colon Cancer Eradication after Chemoimmunotherapy Is Associated with Profound Phenotypic Change of Intratumoral Myeloid Cells

(2010) J. Medina-Echeverz et al.   JOURNAL OF IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Evidence for a cross-talk between human neutrophils and Th17 cells

(2009) M. Pelletier et al.   BLOOD

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

(2009) Zvi G. Fridlender et al.   CANCER CELL

Complement component 5a (C5a)

(2009) Helga D. Manthey et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Polymorphonuclear neutrophils and cancer: Intense and sustained neutrophilia as a treatment against solid tumors

(2009) Juan Carlos Souto et al.   MEDICINAL RESEARCH REVIEWS

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Tumor-specific Th17-polarized cells eradicate large established melanoma

(2008) P. Muranski et al.   BLOOD

Tumour-immune cell interactions modulated by chemokines

(2008) Karin Jöhrer et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Modulation of the antitumor immune response by complement

(2008) Maciej M Markiewski et al.   NATURE IMMUNOLOGY