Delivery of the Pseudomonas aeruginosa Phospholipase Effectors PldA and PldB in a VgrG- and H2-T6SS-Dependent Manner

The gp27-like Hub of VgrG Serves as Adaptor to Promote Hcp Tube Assembly

(2018) Melvin G. Renault et al.   JOURNAL OF MOLECULAR BIOLOGY

A type VI secretion system effector delivery mechanism dependent on PAAR and a chaperone–co-chaperone complex

(2018) Brianne J. Burkinshaw et al.   Nature Microbiology

Mechanism of loading and translocation of type VI secretion system effector Tse6

(2018) Dennis Quentin et al.   Nature Microbiology

The Pseudomonas aeruginosa T6SS-VgrG1b spike is topped by a PAAR protein eliciting DNA damage to bacterial competitors

(2018) Panayiota Pissaridou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Higher Prevalence of PldA, a Pseudomonas aeruginosa Trans-Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains

(2018) Thibaud Boulant et al.   Frontiers in Microbiology

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems inPseudomonas aeruginosa

(2017) Luke P. Allsopp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Pseudomonas T6SS effector recruits PQS-containing outer membrane vesicles for iron acquisition

(2017) Jinshui Lin et al.   Nature Communications

The Hcp proteins fused with diverse extended-toxin domains represent a novel pattern of antibacterial effectors in type VI secretion systems

(2017) Jiale Ma et al.   Virulence

TssA forms a gp6‐like ring attached to the type VI secretion sheath

(2016) Sara Planamente et al.   EMBO JOURNAL

A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery

(2016) Nicolas Flaugnatti et al.   MOLECULAR MICROBIOLOGY

VgrG C terminus confers the type VI effector transport specificity and is required for binding with PAAR and adaptor–effector complex

(2016) Devanand D. Bondage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress

(2016) Feng Jiang et al.   Cell Reports

The structure of VgrG1 fromPseudomonas aeruginosa, the needle tip of the bacterial type VI secretion system

(2016) Mercedes Spínola-Amilibia et al.   Acta Crystallographica Section D-Structural Biology

An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells

(2015) John C. Whitney et al.   CELL

Chimeric adaptor proteins translocate diverse type VI secretion system effectors in Vibrio cholerae

(2015) D. Unterweger et al.   EMBO JOURNAL

Intraspecies Competition in Serratia marcescens Is Mediated by Type VI-Secreted Rhs Effectors and a Conserved Effector-Associated Accessory Protein

(2015) Juliana Alcoforado Diniz et al.   JOURNAL OF BACTERIOLOGY

Biogenesis and structure of a type VI secretion membrane core complex

(2015) Eric Durand et al.   NATURE

Identification of divergent type VI secretion effectors using a conserved chaperone domain

(2015) Xiaoye Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network

(2015) Thibault G. Sana et al.   mBio

The Type VI Secretion TssEFGK-VgrG Phage-Like Baseplate Is Recruited to the TssJLM Membrane Complex via Multiple Contacts and Serves As Assembly Platform for Tail Tube/Sheath Polymerization

(2015) Yannick R. Brunet et al.   PLoS Genetics

A Pseudomonas aeruginosa Type VI Secretion Phospholipase D Effector Targets Both Prokaryotic and Eukaryotic Cells

(2014) Feng Jiang et al.   Cell Host & Microbe

Agrobacterium tumefaciens Deploys a Superfamily of Type VI Secretion DNase Effectors as Weapons for Interbacterial Competition In Planta

(2014) Lay-Sun Ma et al.   Cell Host & Microbe

Type VI secretion and bacteriophage tail tubes share a common assembly pathway

(2014) Y. R. Brunet et al.   EMBO REPORTS

The VgrG Proteins Are “à la Carte” Delivery Systems for Bacterial Type VI Effectors

(2014) Abderrahman Hachani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetically distinct pathways guide effector export through the type VI secretion system

(2014) John C. Whitney et al.   MOLECULAR MICROBIOLOGY

Tit-for-Tat: Type VI Secretion System Counterattack during Bacterial Cell-Cell Interactions

(2013) Marek Basler et al.   CELL

An rhs Gene Linked to the Second Type VI Secretion Cluster Is a Feature of the Pseudomonas aeruginosa Strain PA14

(2013) C. Jones et al.   JOURNAL OF BACTERIOLOGY

Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates

(2013) Julie M. Silverman et al.   MOLECULAR CELL

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors

(2013) Alistair B. Russell et al.   NATURE

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

(2013) Mikhail M. Shneider et al.   NATURE

Structural Characterization and Oligomerization of the TssL Protein, a Component Shared by Bacterial Type VI and Type IVb Secretion Systems

(2012) Eric Durand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phage Pierces the Host Cell Membrane with the Iron-Loaded Spike

(2012) Christopher Browning et al.   STRUCTURE

The Legionella IcmSW Complex Directly Interacts with DotL to Mediate Translocation of Adaptor-Dependent Substrates

(2012) Molly C. Sutherland et al.   PLoS Pathogens

Type VI Secretion System inPseudomonas aeruginosa

(2011) Abderrahman Hachani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type VI secretion delivers bacteriolytic effectors to target cells

(2011) Alistair B. Russell et al.   NATURE

The Vibrio cholerae type VI secretion system displays antimicrobial properties

(2010) D. L. MacIntyre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translocation of a Vibrio cholerae Type VI Secretion Effector Requires Bacterial Endocytosis by Host Cells

(2009) Amy T. Ma et al.   Cell Host & Microbe

Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

(2009) P. G. Leiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type VI secretion: a beginner's guide

(2008) Lewis EH Bingle et al.   CURRENT OPINION IN MICROBIOLOGY