Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway
出版年份 2019 全文链接
标题
Plasma exosomes exacerbate alcohol- and acetaminophen-induced toxicity via CYP2E1 pathway
作者
关键词
-
出版物
Scientific Reports
Volume 9, Issue 1, Pages -
出版商
Springer Nature
发表日期
2019-04-25
DOI
10.1038/s41598-019-43064-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Plasma exosomes as novel biomarker for the early diagnosis of gastric cancer
- (2018) Jianjun Wang et al. Cancer Biomarkers
- Potential neuroprotective role of astroglial exosomes against smoking-induced oxidative stress and HIV-1 replication in the central nervous system
- (2018) Sabina Ranjit et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Exosomes can spread toxic AD pathology
- (2018) Ian Fyfe Nature Reviews Neurology
- In vitro evaluation of structural analogs of diallyl sulfide as novel CYP2E1 inhibitors for their protective effect against xenobiotic-induced toxicity and HIV replication
- (2018) Mohammad A. Rahman et al. TOXICOLOGY LETTERS
- The emerging role of plasma exosomes in diagnosis, prognosis and therapies of patients with cancer
- (2018) Theresa L. Whiteside Wspolczesna Onkologia-Contemporary Oncology
- Co-exposure to benzo[a]pyrene and ethanol induces a pathological progression of liver steatosis in vitro and in vivo
- (2018) Simon Bucher et al. Scientific Reports
- Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure
- (2018) Simon Bucher et al. Oxidative Medicine and Cellular Longevity
- Cytokine profiling of exosomes derived from the plasma of HIV-infected alcohol drinkers and cigarette smokers
- (2018) Sunitha Kodidela et al. PLoS One
- Exogenous exosomes from mice with acetaminophen-induced liver injury promote toxicity in the recipient hepatocytes and mice
- (2018) Young-Eun Cho et al. Scientific Reports
- From Endogenous Compounds as Biomarkers to Plasma‐Derived Nanovesicles as Liquid Biopsy; Has the Golden Age of Translational PK ‐ ADME ‐ DDI Science Finally Arrived?
- (2018) David Rodrigues et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Protective effects of diallyl disulfide against acetaminophen-induced nephrotoxicity: A possible role of CYP2E1 and NF-κB
- (2017) Je-Won Ko et al. FOOD AND CHEMICAL TOXICOLOGY
- MicroRNA profiling in kidney disease: Plasma versus plasma-derived exosomes
- (2017) Jeffrey X. Xie et al. GENE
- Plasma-derived exosomes contribute to inflammation via the TLR9-NF-κB pathway in chronic heart failure patients
- (2017) Wei Ye et al. MOLECULAR IMMUNOLOGY
- MicroRNA Regulation of Oxidative Stress-Induced Cellular Senescence
- (2017) Huaije Bu et al. Oxidative Medicine and Cellular Longevity
- The Role of CYP2E1 in the Drug Metabolism or Bioactivation in the Brain
- (2017) W. A. García-Suástegui et al. Oxidative Medicine and Cellular Longevity
- Monocyte-derived exosomes upon exposure to cigarette smoke condensate alter their characteristics and show protective effect against cytotoxicity and HIV-1 replication
- (2017) Sanjana Haque et al. Scientific Reports
- Chronic Effects of Ethanol and/or Darunavir/Ritonavir on U937 Monocytic Cells: Regulation of Cytochrome P450 and Antioxidant Enzymes, Oxidative Stress, and Cytotoxicity
- (2016) P. S. S. Rao et al. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
- Exosomes: The Messengers of Health and Disease
- (2016) Allison Isola et al. Current Neuropharmacology
- Exosome-associated AAV vector as a robust and convenient neuroscience tool
- (2016) E Hudry et al. GENE THERAPY
- The biological significance and clinical applications of exosomes in ovarian cancer
- (2016) Kalpana Deepa Priya Dorayappan et al. GYNECOLOGIC ONCOLOGY
- Exosomes as therapeutics: The implications of molecular composition and exosomal heterogeneity
- (2016) Scott W. Ferguson et al. JOURNAL OF CONTROLLED RELEASE
- Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles
- (2016) Vikas K. Verma et al. JOURNAL OF HEPATOLOGY
- Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method
- (2016) Narasimha M. Midde et al. PLoS One
- Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?
- (2016) Natalie S. Holman et al. TOXICOLOGICAL SCIENCES
- Effect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways
- (2016) Sabina Ranjit et al. PLoS One
- Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies
- (2015) Anne Stuendl et al. BRAIN
- Role of Metabolic Enzymes P450 (CYP) on Activating Procarcinogen and their Polymorphisms on the Risk of Cancers
- (2015) Xin He et al. CURRENT DRUG METABOLISM
- Exosomes as drug delivery vehicles for Parkinson's disease therapy
- (2015) Matthew J. Haney et al. JOURNAL OF CONTROLLED RELEASE
- Exosomes: Novel Biomarkers for Clinical Diagnosis
- (2015) Jin Lin et al. TheScientificWorldJOURNAL
- Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS
- (2015) Fatemeh Momen-Heravi et al. Scientific Reports
- Enhanced oxidative stress by alcohol use in HIV+ patients: possible involvement of cytochrome P450 2E1 and antioxidant enzymes
- (2015) Anusha Ande et al. AIDS Research and Therapy
- Exosomes: Novel Biomarkers for Clinical Diagnosis
- (2015) Jin Lin et al. Scientific World Journal
- Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
- (2014) Marina Colombo et al. Annual Review of Cell and Developmental Biology
- Iron-mediated effect of alcohol on hepatocyte differentiation in HepaRG cells
- (2013) Thi Hong Tuoi Do et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Oxidative Stress and MicroRNAs in Vascular Diseases
- (2013) Alessandra Magenta et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of cytochrome P450 2e1 expression by ethanol: role of oxidative stress-mediated pkc/jnk/sp1 pathway
- (2013) M Jin et al. Cell Death & Disease
- Alcohol Metabolism
- (2012) Arthur I. Cederbaum Clinics in Liver Disease
- The HepaRG cell line: a uniquein vitrotool for understanding drug metabolism and toxicology in human
- (2012) Tommy B Andersson et al. Expert Opinion on Drug Metabolism & Toxicology
- miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition
- (2011) A Magenta et al. CELL DEATH AND DIFFERENTIATION
- Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes
- (2009) J. E. Laine et al. XENOBIOTICA
- Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes
- (2008) Javier Conde-Vancells et al. JOURNAL OF PROTEOME RESEARCH
- CYP2E1 and oxidative liver injury by alcohol
- (2007) Yongke Lu et al. FREE RADICAL BIOLOGY AND MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation