Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation
出版年份 2019 全文链接
标题
Akt and STAT5 mediate naïve human CD4+ T-cell early metabolic response to TCR stimulation
作者
关键词
-
出版物
Nature Communications
Volume 10, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-05-03
DOI
10.1038/s41467-019-10023-4
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8 + T Cells
- (2018) Glenn R. Bantug et al. IMMUNITY
- Pharmacologic inhibition of STAT5 in acute myeloid leukemia
- (2018) Bettina Wingelhofer et al. LEUKEMIA
- Targeting hepatic glutaminase activity to ameliorate hyperglycemia
- (2018) Russell A Miller et al. NATURE MEDICINE
- Differential Reliance on Lipid Metabolism as a Salvage Pathway Underlies Functional Differences of T Cell Subsets in Poor Nutrient Environments
- (2018) Christopher Ecker et al. Cell Reports
- Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions
- (2018) Ashley V. Menk et al. Cell Reports
- The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling
- (2018) Sara Ricciardi et al. Cell Metabolism
- Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
- (2018) Marc O. Johnson et al. CELL
- Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation
- (2017) Nicholas Jones et al. Frontiers in Immunology
- Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer
- (2016) Sophia Pinz et al. BMC MOLECULAR BIOLOGY
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
- (2016) Rob J.W. Arts et al. Cell Metabolism
- Mitochondrial STAT3: Powering up a potent factor
- (2016) Daniel J. Garama et al. CYTOKINE
- The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements
- (2016) Claudio Procaccini et al. IMMUNITY
- Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma
- (2016) Rana Rais et al. JOURNAL OF MEDICINAL CHEMISTRY
- Reductive carboxylation supports redox homeostasis during anchorage-independent growth
- (2016) Lei Jiang et al. NATURE
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Bioenergetic analysis of human peripheral blood mononuclear cells
- (2015) N. Jones et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The Energy Sensor AMPK Regulates T Cell Metabolic Adaptation and Effector Responses In Vivo
- (2015) Julianna Blagih et al. IMMUNITY
- Metabolic requirements for neutrophil extracellular traps formation
- (2015) Oscar Rodríguez-Espinosa et al. IMMUNOLOGY
- The Immune-Metabolic Basis of Effector Memory CD4+T Cell Function under Hypoxic Conditions
- (2015) Sarah Dimeloe et al. JOURNAL OF IMMUNOLOGY
- Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
- (2015) Emma E. Vincent et al. MOLECULAR CELL
- Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
- (2015) Dorota Klysz et al. Science Signaling
- Normalization of CD4 + T cell metabolism reverses lupus
- (2015) Yiming Yin et al. Science Translational Medicine
- Intersection of mTOR and STAT signaling in immunity
- (2015) Diana Saleiro et al. TRENDS IN IMMUNOLOGY
- LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients
- (2015) Valeria Cazzaniga et al. Oncotarget
- Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation
- (2015) Dorota Klysz et al. Science Signaling
- The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
- (2014) Andrew N. Macintyre et al. Cell Metabolism
- The mTORC1/S6K1 Pathway Regulates Glutamine Metabolism through the eIF4B-Dependent Control of c-Myc Translation
- (2014) Alfredo Csibi et al. CURRENT BIOLOGY
- TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
- (2014) Bart Everts et al. NATURE IMMUNOLOGY
- Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation
- (2014) M Girardot et al. ONCOGENE
- Toward a new STATe: The role of STATs in mitochondrial function
- (2014) Jeremy A. Meier et al. SEMINARS IN IMMUNOLOGY
- Hexokinase–mitochondrial interactions regulate glucose metabolism differentially in adult and neonatal cardiac myocytes
- (2013) Guillaume Calmettes et al. JOURNAL OF GENERAL PHYSIOLOGY
- Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch
- (2013) Patrick M Gubser et al. NATURE IMMUNOLOGY
- CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability
- (2013) G. J. W. van der Windt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β
- (2012) Christina E. Zielinski et al. NATURE
- Interferon-α Regulates Glutaminase 1 Promoter through STAT1 Phosphorylation: Relevance to HIV-1 Associated Neurocognitive Disorders
- (2012) Lixia Zhao et al. PLoS One
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- Protein Kinase B Controls Transcriptional Programs that Direct Cytotoxic T Cell Fate but Is Dispensable for T Cell Metabolism
- (2011) Andrew N. Macintyre et al. IMMUNITY
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
- (2011) Christian M. Metallo et al. NATURE
- Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of -ketoglutarate to citrate to support cell growth and viability
- (2011) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrating Signals from the T-Cell Receptor and the Interleukin-2 Receptor
- (2011) Tilo Beyer et al. PLoS Computational Biology
- Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells
- (2010) Fu-Yu Chueh et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival
- (2010) T. W. Hand et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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