Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

Multi-omics integration reveals molecular networks and regulators of psoriasis

(2019) Yuqi Zhao et al.   BMC Systems Biology

The impact of rare variation on gene expression across tissues

(2017) Xin Li et al.   NATURE

Genetic effects on gene expression across human tissues

(2017) François Aguet et al.   NATURE

Reproducible RNA-seq analysis using recount2

(2017) Leonardo Collado-Torres et al.   NATURE BIOTECHNOLOGY

Declining Risk of Sudden Death in Heart Failure

(2017) Li Shen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A complete tool set for molecular QTL discovery and analysis

(2017) Olivier Delaneau et al.   Nature Communications

Colocalization of GWAS and eQTL Signals Detects Target Genes

(2016) Farhad Hormozdiari et al.   AMERICAN JOURNAL OF HUMAN GENETICS

FINEMAP: efficient variable selection using summary data from genome-wide association studies

(2016) Christian Benner et al.   BIOINFORMATICS

Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples

(2016) Roddy Walsh et al.   GENETICS IN MEDICINE

[Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction

(2015) Vahid Serpooshan et al.   BIOMATERIALS

Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation

(2015) Simon R. Foster et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

FastRFunctions for Robust Correlations and Hierarchical Clustering

(2015) Peter Langfelder et al.   Journal of Statistical Software

SNPsnap: a Web-based tool for identification and annotation of matched SNPs

(2014) Tune H. Pers et al.   BIOINFORMATICS

SNiPA: an interactive, genetic variant-centered annotation browser

(2014) Matthias Arnold et al.   BIOINFORMATICS

Bitter taste receptor agonists elicit G-protein-dependent negative inotropy in the murine heart

(2014) Simon R. Foster et al.   FASEB JOURNAL

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

A Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease

(2013) Tianxiao Huan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

The joint graphical lasso for inverse covariance estimation across multiple classes

(2013) Patrick Danaher et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart

(2013) Simon R. Foster et al.   PLoS One

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Comparison of co-expression measures: mutual information, correlation, and model based indices

(2012) Lin Song et al.   BMC BIOINFORMATICS

Annotation of functional variation in personal genomes using RegulomeDB

(2012) A. P. Boyle et al.   GENOME RESEARCH

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

(2012) Oliver Stegle et al.   Nature Protocols

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

The Economics of Heart Failure

(2012) Dhruv S. Kazi et al.   Heart Failure Clinics

Functional Genomics Applied to Cardiovascular Medicine

(2011) Thomas P. Cappola et al.   CIRCULATION

Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine Hearts

(2011) Jae-Hyung Lee et al.   CIRCULATION RESEARCH

Gene Coexpression Network Topology of Cardiac Development, Hypertrophy, and Failure

(2010) Frederick E. Dewey et al.   Circulation-Cardiovascular Genetics

Genomics, Transcriptional Profiling, and Heart Failure

(2009) Kenneth B. Margulies et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial expression, signaling, and function of GPR22: a protective role for an orphan G protein-coupled receptor

(2008) John W. Adams et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Tackling heart failure in the twenty-first century

(2008) James O. Mudd et al.   NATURE

A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice

(2008) David B Savage et al.   PLOS MEDICINE