Multi-omics integration reveals molecular networks and regulators of psoriasis

Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease

(2018) Karthickeyan Chella Krishnan et al.   Cell Systems

Epigenetics of psoriatic disease: A systematic review and critical appraisal

(2017) Remy A. Pollock et al.   JOURNAL OF AUTOIMMUNITY

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

(2017) Lam C. Tsoi et al.   Nature Communications

Shared genetic regulatory networks for cardiovascular disease and type 2 diabetes in multiple populations of diverse ethnicities in the United States

(2017) Le Shu et al.   PLoS Genetics

Novel metabolic and physiological functions of branched chain amino acids: a review

(2017) Shihai Zhang et al.   Journal of Animal Science and Biotechnology

Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease LociSignificance

(2016) Yuqi Zhao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems

(2016) Le Shu et al.   BMC GENOMICS

Genome-Wide Pathway Analysis Identifies Genetic Pathways Associated with Psoriasis

(2016) Adrià Aterido et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

One SNP at a Time: Moving beyond GWAS in Psoriasis

(2016) Helen Ray-Jones et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Avoiding Data Dumpsters — Toward Equitable and Useful Data Sharing

(2016) Laura Merson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of Molecular Signatures from Multiple Skin Diseases Identifies Mechanisms of Immunopathogenesis

(2015) Megan S. Inkeles et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Understanding multicellular function and disease with human tissue-specific networks

(2015) Casey S Greene et al.   NATURE GENETICS

The IL-23–IL-17 axis in inflammatory arthritis

(2015) Erik Lubberts   Nature Reviews Rheumatology

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Update on psoriasis immunopathogenesis and targeted immunotherapy

(2015) Satveer K. Mahil et al.   Seminars in Immunopathology

Multiscale Embedded Gene Co-expression Network Analysis

(2015) Won-Min Song et al.   PLoS Computational Biology

Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin

(2015) Lam C Tsoi et al.   GENOME BIOLOGY

Integrative clinical transcriptomics analyses for new therapeutic intervention strategies: a psoriasis case study

(2014) Xiaoyan A. Qu et al.   DRUG DISCOVERY TODAY

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

(2014) Christian Cole et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Correction: Cathepsin K is Involved in Development of Psoriasis-like Skin Lesions through TLR-Dependent Th17 Activation

(2014) T. Hirai et al.   JOURNAL OF IMMUNOLOGY

Branched-chain amino acids in metabolic signalling and insulin resistance

(2014) Christopher J. Lynch et al.   Nature Reviews Endocrinology

Integrative Genomics Reveals Novel Molecular Pathways and Gene Networks for Coronary Artery Disease

(2014) Ville-Petteri Mäkinen et al.   PLoS Genetics

The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts

(2014) James R Wagner et al.   GENOME BIOLOGY

A Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease

(2013) Tianxiao Huan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heritability of psoriasis in a large twin sample

(2013) A.S. Lønnberg et al.   BRITISH JOURNAL OF DERMATOLOGY

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

Whole-genome DNA methylation in skin lesions from patients with psoriasis vulgaris

(2013) Peng Zhang et al.   JOURNAL OF AUTOIMMUNITY

Expression quantitative trait loci: present and future

(2013) A. C. Nica et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The automation of systematic reviews

(2013) G. Tsafnat et al.   BMJ-British Medical Journal

Transcriptome classification reveals molecular subtypes in psoriasis

(2012) Chrysanthi Ainali et al.   BMC GENOMICS

The Genetics of Psoriasis and Psoriatic Arthritis

(2012) Vinod Chandran   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Epigenetics and psoriasis

(2011) P. Zhang et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

The Mouse Genome Database (MGD): comprehensive resource for genetics and genomics of the laboratory mouse

(2011) J. T. Eppig et al.   NUCLEIC ACIDS RESEARCH

Gene Coexpression Network Alignment and Conservation of Gene Modules between Two Grass Species: Maize and Rice

(2011) S. P. Ficklin et al.   PLANT PHYSIOLOGY

Platelet P-selectin reflects a state of cutaneous inflammation: possible application to monitor treatment efficacy in psoriasis

(2010) Jurate Garbaraviciene et al.   EXPERIMENTAL DERMATOLOGY

Angiogenesis drives psoriasis pathogenesis

(2010) Regina Heidenreich et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection

(2010) I. K. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Upregulation of cathepsin S in psoriatic keratinocytes

(2009) Alexander Schönefuß et al.   EXPERIMENTAL DERMATOLOGY

The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis

(2009) Antonella Di Cesare et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

PolySearch: a web-based text mining system for extracting relationships between human diseases, genes, mutations, drugs and metabolites

(2008) D. Cheng et al.   NUCLEIC ACIDS RESEARCH