Rapid molecular evolution of pain insensitivity in multiple African rodents

Structure of the human voltage-gated sodium channel Nav1.4 in complex with β1

(2018) Xiaojing Pan et al.   SCIENCE

Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers

(2017) Laura-Nadine Schuhmacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for animal nociception

(2017) Oscar M. Arenas et al.   NATURE NEUROSCIENCE

Fructose-driven glycolysis supports anoxia resistance in the naked mole-rat

(2017) Thomas J. Park et al.   SCIENCE

Sensitivities of Two Zebrafish TRPA1 Paralogs to Chemical and Thermal Stimuli Analyzed in Heterologous Expression Systems

(2016) Mai Oda et al.   CHEMICAL SENSES

TransRate: reference-free quality assessment of de novo transcriptome assemblies

(2016) Richard Smith-Unna et al.   GENOME RESEARCH

Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat

(2016) Damir Omerbašić et al.   Cell Reports

BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs

(2015) Felipe A. Simão et al.   BIOINFORMATICS

Family Wide Molecular Adaptations to Underground Life in African Mole-Rats Revealed by Phylogenomic Analysis

(2015) Kalina T.J. Davies et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structure of the TRPA1 ion channel suggests regulatory mechanisms

(2015) Candice E. Paulsen et al.   NATURE

Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway

(2015) Alban Latremoliere et al.   NEURON

GUIDANCE2: accurate detection of unreliable alignment regions accounting for the uncertainty of multiple parameters

(2015) Itamar Sela et al.   NUCLEIC ACIDS RESEARCH

Bridger: a new framework for de novo transcriptome assembly using RNA-seq data

(2015) Zheng Chang et al.   GENOME BIOLOGY

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

(2014) Susannah J Salter et al.   BMC BIOLOGY

Heat and Noxious Chemical Sensor, Chicken TRPA1, as a Target of Bird Repellents and Identification of Its Structural Determinants by Multispecies Functional Comparison

(2014) Shigeru Saito et al.   MOLECULAR BIOLOGY AND EVOLUTION

Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing

(2014) Dmitry Usoskin et al.   NATURE NEUROSCIENCE

Structure and Function of TMEM16 Proteins (Anoctamins)

(2014) Nicoletta Pedemonte et al.   PHYSIOLOGICAL REVIEWS

A newly recognized family from the Horn of Africa, the Heterocephalidae (Rodentia: Ctenohystrica)

(2014) Bruce D. Patterson et al.   ZOOLOGICAL JOURNAL OF THE LINNEAN SOCIETY

The sodium leak channel, NALCN, in health and disease

(2014) Maud Cochet-Bissuel et al.   Frontiers in Cellular Neuroscience

Fragment assignment in the cloud with eXpress-D

(2013) Adam Roberts et al.   BMC BIOINFORMATICS

Assessing De Novo transcriptome assembly metrics for consistency and utility

(2013) Shawn T O’Neil et al.   BMC GENOMICS

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

TMEM16C facilitates Na+-activated K+ currents in rat sensory neurons and regulates pain processing

(2013) Fen Huang et al.   NATURE NEUROSCIENCE

De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis

(2013) Brian J Haas et al.   Nature Protocols

RefSeq: an update on mammalian reference sequences

(2013) Kim D. Pruitt et al.   NUCLEIC ACIDS RESEARCH

Repeated functional convergent effects of NaV1.7 on acid insensitivity in hibernating mammals

(2013) Z. Liu et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Voltage-Gated Sodium Channel in Grasshopper Mice Defends Against Bark Scorpion Toxin

(2013) A. H. Rowe et al.   SCIENCE

Predicting dispersal distance in mammals: a trait-based approach

(2012) Sarah Whitmee et al.   JOURNAL OF ANIMAL ECOLOGY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

TWIK1, a unique background channel with variable ion selectivity

(2012) F. C. Chatelain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiobjective evolutionary algorithms to identify highly autocorrelated areas: the case of spatial distribution in financially compromised farms

(2011) Carlos R. García-Alonso et al.   ANNALS OF OPERATIONS RESEARCH

A TRPA1-dependent mechanism for the pungent sensation of weak acids

(2011) Yuanyuan Y. Wang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Phylogeography and cryptic diversity of the solitary-dwelling silvery mole-rat, genus Heliophobius (family: Bathyergidae)

(2011) C. G. Faulkes et al.   JOURNAL OF ZOOLOGY

An Improved Likelihood Ratio Test for Detecting Site-Specific Functional Divergence among Clades of Protein-Coding Genes

(2011) Cameron J. Weadick et al.   MOLECULAR BIOLOGY AND EVOLUTION

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

(2011) Christopher J. Bohlen et al.   NATURE

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

The Molecular Basis of Acid Insensitivity in the African Naked Mole-Rat

(2011) E. S. J. Smith et al.   SCIENCE

Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception

(2010) Kyeongjin Kang et al.   NATURE

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Many-core algorithms for statistical phylogenetics

(2009) M. A. Suchard et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

The NALCN ion channel is activated by M3 muscarinic receptors in a pancreatic β-cell line

(2009) Leigh Anne Swayne et al.   EMBO REPORTS

Nociceptors: a phylogenetic view

(2009) Ewan St. John Smith et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY

Selective Inflammatory Pain Insensitivity in the African Naked Mole-Rat (Heterocephalus glaber)

(2008) Thomas J Park et al.   PLOS BIOLOGY