9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII

Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones

(2015) Akın Akıncıoğlu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II

(2015) Alper Yıldırım et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of 4-[2-(3,4-dimethoxybenzyl)cyclopentyl]-1,2-dimethoxybenzene Derivatives and Evaluations of Their Carbonic Anhydrase Isoenzymes Inhibitory Effects

(2015) Tekin Artunç et al.   Chemical Biology & Drug Design

Synthesis of some acrylophenones withN-methylpiperazine and evaluation of their cytotoxicities

(2015) Halise Inci Gul et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII)

(2015) Andrea Scozzafava et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Antioxidant, antiradical, and anticholinergic properties of cynarin purified from the Illyrian thistle (Onopordum illyricumL.)

(2015) Meryem Topal et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives

(2015) Parham Taslimi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing Tumors

(2014) Nikolaus Krall et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Carbonic Anhydrase Isoenzymes Inhibitory Effects of Brominated Diphenylmethanone and Its Derivatives

(2014) Yasin Çetinkaya et al.   ARCHIV DER PHARMAZIE

Oxidation of cyanobenzocycloheptatrienes: Synthesis, photooxygenation reaction and carbonic anhydrase isoenzymes inhibition properties of some new benzotropone derivatives

(2014) Murat Güney et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and evaluation of N-substituted saccharin derivatives as selective inhibitors of tumor-associated carbonic anhydrase XII

(2014) Melissa D’Ascenzio et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitory properties of novel benzylsulfamides using molecular modeling and experimental studies

(2014) Süleyman Göksu et al.   BIOORGANIC CHEMISTRY

Cyclic tertiary sulfamates: Selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives

(2014) Celeste De Monte et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrase and acetylcholinesterase inhibitory effects of carbamates and sulfamoylcarbamates

(2014) Hülya Göçer et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors: guaiacol and catechol derivatives effectively inhibit certain human carbonic anhydrase isoenzymes (hCA I, II, IX and XII)

(2014) Andrea Scozzafava et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Synthesis and Carbonic Anhydrase Isoenzymes I, II, IX, and XII Inhibitory Effects of Dimethoxybromophenol Derivatives Incorporating Cyclopropane Moieties

(2014) Murat Boztaş et al.   JOURNAL OF MEDICINAL CHEMISTRY

Capsaicin: A Potent Inhibitor of Carbonic Anhydrase Isoenzymes

(2014) Betul Arabaci et al.   MOLECULES

Rosmarinic acid: a potent carbonic anhydrase isoenzymes inhibitor

(2014) Meryem TOPAL et al.   TURKISH JOURNAL OF CHEMISTRY

Novel Sulphamides and Sulphonamides Incorporating the Tetralin Scaffold as Carbonic Anhydrase and Acetylcholine Esterase Inhibitors

(2013) Akın Akıncıoğlu et al.   ARCHIV DER PHARMAZIE

Synthesis, Antioxidant, and Antiacetylcholinesterase Activities of Sulfonamide Derivatives of Dopamine-Related Compounds

(2013) Hülya Göçer et al.   ARCHIV DER PHARMAZIE

Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors

(2013) Akın Akıncıoğlu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides

(2013) Atilla Akdemir et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including Acetazolamide in human Glioblastoma

(2013) Harun M. Said et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells

(2013) Tania Fiaschi et al.   CELL CYCLE

Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IX

(2013) Aditi Sharma et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Carbonic anhydrases: from biomedical applications of the inhibitors and activators to biotechnological use for CO2 capture

(2013) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Molecular structures and biological evaluation of 2-chloro-3-(n-alkylamino)-1,4-napthoquinone derivatives as potent antifungal agents

(2013) Omkar Pawar et al.   JOURNAL OF MOLECULAR STRUCTURE

Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice

(2013) Benjamin D. Sachs et al.   NEUROPHARMACOLOGY

Inhibition of Carbonic Anhydrase IX: A New Strategy Against Cancer

(2012) Jean-Yves Winum et al.   Anti-Cancer Agents in Medicinal Chemistry

Carbonic anhydrase inhibitors: Benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII

(2012) Ahmed M. Alafeefy et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

Carbonic Anhydrase IX Promotes Tumor Growth and Necrosis In Vivo and Inhibition Enhances Anti-VEGF Therapy

(2012) A. McIntyre et al.   CLINICAL CANCER RESEARCH

Dihalogenated sulfanilamides and benzolamides are effective inhibitors of the three β-class carbonic anhydrases fromMycobacterium tuberculosis

(2012) Alfonso Maresca et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Metronidazole-coumarin conjugates and 3-cyano-7-hydroxy-coumarin act as isoform-selective carbonic anhydrase inhibitors

(2012) Adeline Bonneau et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Structure-based drug discovery of carbonic anhydrase inhibitors

(2012) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inhibition of the β-class carbonic anhydrases fromMycobacterium tuberculosiswith carboxylic acids

(2012) Alfonso Maresca et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Adolescent male rats are less sensitive than adults to the anxiogenic and serotonin-releasing effects of fenfluramine

(2012) Andrew E. Arrant et al.   NEUROPHARMACOLOGY

Targeting carbonic anhydrase IX depletes breast cancer stem cells within the hypoxic niche

(2012) F E Lock et al.   ONCOGENE

Synthesis and Antioxidant Properties of (3,4-Dihydroxyphenyl)(2,3,4-trihydroxyphenyl)methanone and Its Derivatives

(2011) Yasin Çetinkaya et al.   ARCHIV DER PHARMAZIE

Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds

(2011) M. Sortino et al.   BIOORGANIC & MEDICINAL CHEMISTRY

In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds

(2011) Sevim Beyza Öztürk Sarikaya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors

(2011) Y. Lou et al.   CANCER RESEARCH

In Vitro Inhibition of Human Carbonic Anhydrase I and II Isozymes with Natural Phenolic Compounds

(2011) Murat Şentürk et al.   Chemical Biology & Drug Design

Carbonic anhydrase inhibitors and activators for novel therapeutic applications

(2011) Claudiu T Supuran   Future Medicinal Chemistry

Purification and Characterization of Peroxidase from Sweet Gourd (Cucurbita moschataLam. Poiret)

(2011) Ekrem Koksal et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

The Inhibitory Effects of L-Adrenaline on Lactoperoxidase Enzyme Purified from Bovine Milk

(2011) Melda Şisecioglu et al.   INTERNATIONAL JOURNAL OF FOOD PROPERTIES

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Maleimide-DimethylfuranexoAdducts: Effective Maleimide Protection in the Synthesis of Oligonucleotide Conjugates

(2011) Albert Sánchez et al.   ORGANIC LETTERS

Carbonic anhydrase inhibitors

(2010) Claudiu T. Supuran   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Drug Design Studies of the Novel Antitumor Targets Carbonic Anhydrase IX and XII

(2010) O. Guler et al.   CURRENT MEDICINAL CHEMISTRY

Antifungal therapy in invasive fungal infections

(2010) Sharon C-A Chen et al.   CURRENT OPINION IN PHARMACOLOGY

Carbonic Anhydrase Inhibition/Activation: Trip of a Scientist Around the World in the Search of Novel Chemotypes and Drug Targets

(2010) Claudiu T. Supuran   CURRENT PHARMACEUTICAL DESIGN

Carbonic anhydrase inhibition with natural products: novel chemotypes and inhibition mechanisms

(2010) Claudiu T. Supuran   MOLECULAR DIVERSITY

Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target

(2009) Giuseppina De Simone et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols

(2009) Murat Şentürk et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I–XIV

(2009) T. Abdülkadir Coban et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies

(2009) Peter Ebbesen et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Substituent chemical shifts ofN-arylsuccinanilic acids,N-arylsuccinimides,N-arylmaleanilic acids, andN-arylmaleimides

(2009) Hye Sun Lee et al.   MAGNETIC RESONANCE IN CHEMISTRY

Dantrolene Inhibits Human Erythrocyte Glutathione Reductase

(2008) Murat Şentürk et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cancer-Associated Carbonic Anhydrases and Their Inhibition

(2008) J. Pastorek et al.   CURRENT PHARMACEUTICAL DESIGN

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Purification and Characterization of Peroxidase from Cauliflower (Brassica oleracea L. var. botrytis) Buds

(2008) Ekrem Koksal et al.   PROTEIN AND PEPTIDE LETTERS

Regulation of extracellular serotonin levels and brain-derived neurotrophic factor in rats with high and low exploratory activity

(2007) Tanel Mällo et al.   BRAIN RESEARCH

Carbonic anhydrase IX: A new druggable target for the design of antitumor agents

(2007) Jean-Yves Winum et al.   MEDICINAL RESEARCH REVIEWS