标题
Progranulin deficiency leads to reduced glucocerebrosidase activity
作者
关键词
Lysosomes, Immunoprecipitation, Cell binding assay, Mouse models, Recombination-based assay, Recombinant proteins, Fibroblasts, Stable isotope labeling by amino acids in cell culture
出版物
PLoS One
Volume 14, Issue 7, Pages e0212382
出版商
Public Library of Science (PLoS)
发表日期
2019-07-11
DOI
10.1371/journal.pone.0212382
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The role of glucocerebrosidase in Parkinson disease pathogenesis
- (2018) Matthew E. Gegg et al. FEBS Journal
- Genotype–phenotype links in frontotemporal lobar degeneration
- (2018) Sara Van Mossevelde et al. Nature Reviews Neurology
- Evidence of Pre-Synaptic Dopaminergic Deficit in a Patient with a Novel Progranulin Mutation Presenting with Atypical Parkinsonism†
- (2018) Miryam Carecchio et al. JOURNAL OF ALZHEIMERS DISEASE
- Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients
- (2017) Clarissa Valdez et al. HUMAN MOLECULAR GENETICS
- The lysosomal protein cathepsin L is a progranulin protease
- (2017) Chris W. Lee et al. Molecular Neurodegeneration
- Lysosomal processing of progranulin
- (2017) Xiaolai Zhou et al. Molecular Neurodegeneration
- Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations
- (2017) Xiaolai Zhou et al. Nature Communications
- Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency
- (2017) Bret M. Evers et al. Cell Reports
- Portuguese family with the co-occurrence of frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis phenotypes due to progranulin gene mutation
- (2016) Maria R. Almeida et al. NEUROBIOLOGY OF AGING
- Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease
- (2016) Jinlong Jian et al. EBioMedicine
- Association Between Progranulin and Gaucher Disease
- (2016) Jinlong Jian et al. EBioMedicine
- Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
- (2015) Xiaolai Zhou et al. JOURNAL OF CELL BIOLOGY
- Association of progranulin polymorphism rs5848 with neurodegenerative diseases: a meta-analysis
- (2015) Yongdui Chen et al. JOURNAL OF NEUROLOGY
- The Evolution of the Secreted Regulatory Protein Progranulin
- (2015) Roger G. E. Palfree et al. PLoS One
- Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes
- (2015) Daniela Herrera Moro Chao et al. PLoS One
- Progranulin Gene Delivery Protects Dopaminergic Neurons in a Mouse Model of Parkinson’s Disease
- (2014) Jackalina M. Van Kampen et al. PLoS One
- Reduced serum progranulin level might be associated with Parkinson's disease risk
- (2013) I. Mateo et al. EUROPEAN JOURNAL OF NEUROLOGY
- Association between GRN rs5848 Polymorphism and Parkinson′s Disease in Taiwanese Population
- (2013) Kuo-Hsuan Chang et al. PLoS One
- Expression of the Growth Factor Progranulin in Endothelial Cells Influences Growth and Development of Blood Vessels: A Novel Mouse Model
- (2013) Huishi Toh et al. PLoS One
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage
- (2012) Katherine R. Smith et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Progranulin: A Proteolytically Processed Protein at the Crossroads of Inflammation and Neurodegeneration
- (2012) Basar Cenik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Insights into the role of progranulin in immunity, infection, and inflammation
- (2012) J. Jian et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The role of saposin C in Gaucher disease
- (2012) Rafael J. Tamargo et al. MOLECULAR GENETICS AND METABOLISM
- Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice
- (2012) Y. Tanaka et al. NEUROSCIENCE
- Structure, Function, and Mechanism of Progranulin; the Brain and Beyond
- (2011) Huishi Toh et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function
- (2011) Vincenzo Belcastro et al. NUCLEIC ACIDS RESEARCH
- Development and application of mass spectrometric methods for the analysis of progranulin N-glycosylation
- (2010) Kriangsak Songsrirote et al. Journal of Proteomics
- Ultrasensitive in situ visualization of active glucocerebrosidase molecules
- (2010) Martin D Witte et al. Nature Chemical Biology
- Sortilin-Mediated Endocytosis Determines Levels of the Frontotemporal Dementia Protein, Progranulin
- (2010) Fenghua Hu et al. NEURON
- Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice
- (2009) Fangfang Yin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
- (2009) E. Sidransky et al. NEW ENGLAND JOURNAL OF MEDICINE
- Deletion of the progranulin gene in patients with frontotemporal lobar degeneration or Parkinson disease
- (2008) Anne Rovelet-Lecrux et al. NEUROBIOLOGY OF DISEASE
- Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities
- (2008) Dmitri Tolkatchev et al. PROTEIN SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now