In silico analysis of PFN1 related to amyotrophic lateral sclerosis

A molecular dynamics study of adenylyl cyclase: The impact of ATP and G-protein binding

(2018) Elisa Frezza et al.   PLoS One

How accurately do force fields represent protein side chain ensembles?

(2018) Dušan Petrović et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Proteostasis disturbance in amyotrophic lateral sclerosis

(2017) Danilo B. Medinas et al.   HUMAN MOLECULAR GENETICS

PMut: a web-based tool for the annotation of pathological variants on proteins, 2017 update

(2017) Víctor López-Ferrando et al.   NUCLEIC ACIDS RESEARCH

DSSR-enhanced visualization of nucleic acid structures in Jmol

(2017) Robert M. Hanson et al.   NUCLEIC ACIDS RESEARCH

Protein Binding Pocket Dynamics

(2016) Antonia Stank et al.   ACCOUNTS OF CHEMICAL RESEARCH

Profilin1 biology and its mutation, actin(g) in disease

(2016) Duah Alkam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Current updates on computer aided protein modeling and designing

(2016) Faez Iqbal Khan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Large-scale screening in sporadic amyotrophic lateral sclerosis identifies genetic modifiers in C9orf72 repeat carriers

(2016) Annelot M. Dekker et al.   NEUROBIOLOGY OF AGING

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase

(2016)   NUCLEIC ACIDS RESEARCH

Impact of germline and somatic missense variations on drug binding sites

(2016) C Yan et al.   PHARMACOGENOMICS JOURNAL

Amyotrophic Lateral Sclerosis Type 20 - In Silico Analysis and Molecular Dynamics Simulation of hnRNPA1

(2016) Bruna Baumgarten Krebs et al.   PLoS One

Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity

(2016) Chunxing Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for mutation-induced destabilization of profilin 1 in ALS

(2015) Sivakumar Boopathy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Automatic Identification of Mobile and Rigid Substructures in Molecular Dynamics Simulations and Fractional Structural Fluctuation Analysis

(2015) Leandro Martínez   PLoS One

Pathogenesis/genetics of frontotemporal dementia and how it relates to ALS

(2014) Janis Bennion Callister et al.   EXPERIMENTAL NEUROLOGY

Protein aggregation due to nsSNP resulting in P56S VABP protein is associated with amyotrophic lateral sclerosis

(2014) Chundi Vinay Kumar et al.   JOURNAL OF THEORETICAL BIOLOGY

High-throughput mutagenesis reveals functional determinants for DNA targeting by activation-induced deaminase

(2014) Kiran S. Gajula et al.   NUCLEIC ACIDS RESEARCH

Economic burden of amyotrophic lateral sclerosis: A Canadian study of out-of-pocket expenses

(2014) Matthew Gladman et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

WS-SNPs&GO: a web server for predicting the deleterious effect of human protein variants using functional annotation

(2013) Emidio Capriotti et al.   BMC GENOMICS

JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied toProteopedia

(2013) Robert M. Hanson et al.   ISRAEL JOURNAL OF CHEMISTRY

The changing scene of amyotrophic lateral sclerosis

(2013) Wim Robberecht et al.   NATURE REVIEWS NEUROSCIENCE

Structural and Functional Analysis of Human SOD1 in Amyotrophic Lateral Sclerosis

(2013) Lorenna Giannini Alves Moreira et al.   PLoS One

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

(2012) Chi-Hong Wu et al.   NATURE

A novel phosphorylation site mutation in profilin 1 revealed in a large screen of US, Nordic, and German amyotrophic lateral sclerosis/frontotemporal dementia cohorts

(2012) Caroline Ingre et al.   NEUROBIOLOGY OF AGING

Molecular insights on context-specific role of profilin-1 in cell migration

(2012) Zhijie Ding et al.   Cell Adhesion & Migration

Is an Intuitive Convergence Definition of Molecular Dynamics Simulations Solely Based on the Root Mean Square Deviation Possible?

(2011) B. Knapp et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants

(2011) G. De Baets et al.   NUCLEIC ACIDS RESEARCH

Determination of Ensemble-Average Pairwise Root Mean-Square Deviation from Experimental B-Factors

(2010) Antonija Kuzmanic et al.   BIOPHYSICAL JOURNAL

Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces

(2010) Hanka Venselaar et al.   BMC BIOINFORMATICS

Next generation tools for the annotation of human SNPs

(2009) Rachel Karchin   BRIEFINGS IN BIOINFORMATICS

Both actin and polyproline interactions of profilin-1 are required for migration, invasion and capillary morphogenesis of vascular endothelial cells

(2009) Zhijie Ding et al.   EXPERIMENTAL CELL RESEARCH

Pathogenic or not? And if so, then how? Studying the effects of missense mutations using bioinformatics methods

(2009) Janita Thusberg et al.   HUMAN MUTATION

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation