Article
Cell Biology
Timothy Kudinha, Fanrong Kong
Summary: The prevalence of ST131, especially among ciprofloxacin resistant isolates, increased from fecal to clinical samples in women, men, and children. ST131 isolates showed higher virulence potential compared to non-ST131 isolates, particularly in urinary samples. There was a strong association between ST131 prevalence and fluoroquinolone resistance, with FQ resistant ST131 isolates harboring more virulence genes.
JOURNAL OF BIOMEDICAL SCIENCE
(2022)
Article
Microbiology
Saleh Afsharikhah, Reza Ghanbarpour, Parvin Mohseni, Nasrin Adib, Mahboube Bagheri, Maziar Jajarmi
Summary: This study aimed to assess the prevalence of common beta-lactam resistance genes and phenotypic resistance in urinary tract infections caused by Escherichia coli isolates. The results showed high prevalence of antibiotic resistance to beta-lactams and fluoroquinolones, suggesting the need for changes in drug resistance diagnosis and antibiotic therapy strategies.
Article
Microbiology
Timothy J. Dallman, Saskia Neuert, Cristina Fernandez Turienzo, Michelle Berin, Emily Richardson, Pablo Fuentes-Utrilla, Nicholas Loman, Saheer Gharbia, Claire Jenkins, Ron H. Behrens, Gauri Godbole, Michael Brown
Summary: International travel is a risk factor for acquisition of resistant organisms, as shown by increased abundance and diversity of antibiotic resistance genes in fecal samples post-travel. Resistance genes for macrolides, third-generation cephalosporins, aminoglycosides, and sulfonamides were particularly increased. The study also found a significant association between diarrhea or antibiotic use and increased resistome abundance.
MICROBIOLOGY SPECTRUM
(2023)
Article
Agriculture, Dairy & Animal Science
Beatriz Garcia-Bejar, Izan Garcia de Blas Martin, Maria Arevalo-Villena, Ana Briones Perez
Summary: The study investigates the prevalence of antibiotic resistance in Escherichia coli found in poultry products in Spain, revealing high resistance rates to multiple antibiotics, especially colistin and gentamicin. The majority resistance genes were found to be tet(A) and blaTEM.
Article
Environmental Sciences
William Calero-Caceres, Daniel Tadesse, Katherine Jaramillo, Xavier Villavicencio, Efrain Mero, Liliana Lalaleo, Caitlin Welsh, Jose E. Villacis, Emmanuelle Quentin, Henry Parra, Maria Soledad Ramirez, Anthony D. Harries, Jose L. Balcazar
Summary: Although human activities contribute to antibiotic resistance in aquatic environments, limited information is available on the impact of discharges from countries with inadequate sewage treatment systems. This study found multidrug-resistant Escherichia coli isolates in Ecuadorian environmental samples, with some isolates carrying the mcr-1 gene along with other resistance genes.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Infectious Diseases
Weidong Qian, Xinchen Li, Min Yang, Chanchan Liu, Yi Kong, Yongdong Li, Ting Wang, Qian Zhang
Summary: This study investigated the association between biofilm formation and antibiotic resistance in extensively drug-resistant Escherichia coli isolates. The results showed that stronger biofilm formation was correlated with larger proportions of extensively drug-resistant isolates. These findings provide novel insights for the prevention and treatment of E. coli-related infections.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Infectious Diseases
Weidong Qian, Xinchen Li, Min Yang, Chanchan Liu, Yi Kong, Yongdong Li, Ting Wang, Qian Zhang
Summary: This study evaluated the antibiotic resistance/susceptibility profiles and biofilm-forming capacities of 81 Escherichia coli isolates from pediatric individuals in China, revealing an association between biofilm formation and resistance to several antibiotics for extensively drug-resistant strains. This finding provides novel insights for the prevention and treatment against E. coli-related infections.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Microbiology
Runhao Yu, Zheng Chen, Stefan Schwarz, Hong Yao, Xiang-Dang Du
Summary: The dissemination mechanism of the high-level tigecycline resistance gene tet(X4) in porcine Escherichia coli was investigated, and it was demonstrated that IS1A mediates the transposition of tet(X4) into the E. coli chromosome.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2022)
Article
Microbiology
Aspen Kremer, Grant Whitmer, Alondra Diaz, Alima Sajwani, Alexis Navarro, Mehreen Arshad
Summary: ESBL-producing Escherichia coli strains in the gut may have enhanced fitness and antimicrobial resistance. Using a mouse model, it was confirmed that ESBL E. coli strains have a strong ability to colonize the infant gut, even in the absence of antibiotic pressure.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
Katerina Tsilipounidaki, Zoi Florou, Anargyros Skoulakis, George C. C. Fthenakis, Vivi Miriagou, Efthymia Petinaki
Summary: The present study genetically characterized ten NDM-1 producing Escherichia coli isolates from a hospital in Central Greece between 2017 and 2021. Whole genome sequencing was used to determine the multi-locus sequencing typing (MLST), bla(NDM1)-environment, resistome, and plasmid content. The isolates showed a diverse range of sequence types and carried multiple resistance genes to beta-lactams and other classes of antibiotics. The analysis also revealed the presence of various plasmids, indicating continuous horizontal gene transfer among the isolates.
Article
Engineering, Environmental
Zahra Shamsizadeh, Mohammad Hassan Ehrampoush, Mahnaz Nikaeen, Mehdi Mokhtari, Mahsa Rahimi, Hossein Khanahmad, Farzaneh Mohammadi
Summary: The study found that agricultural reuse of treated wastewater may contribute to the dissemination of antibiotic-resistant bacteria and genes in the environment, posing a potential risk to public health.
WATER SCIENCE AND TECHNOLOGY
(2021)
Article
Immunology
Achiraya Siriphap, Thawatchai Kitti, Akachai Khuekankaew, Chalermchai Boonlao, Chonthida Thephinlap, Chutamas Thepmalee, Nittiya Suwannasom, Krissana Khoothiam
Summary: This study investigated the prevalence of ESBL-positive E. coli and K. pneumoniae isolates from hospitalized patients in Chiangrai Prachanukroh hospital, Thailand. The study found a high prevalence and emerging antibiotic resistance of ESBL-positive strains, indicating the need for carbapenems and aminoglycosides as the first-line drugs.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Environmental Sciences
Ziqi Zhu, Shaoqi Jiang, Mingyu Qi, Haifeng Liu, Shaqiu Zhang, Hang Liu, Ziyao Zhou, Liqin Wang, Chengdong Wang, Yan Luo, Zhihua Ren, Xiaoping Ma, Suizhong Cao, Liuhong Shen, Ya Wang, Hualin Fu, Yi Geng, Changliang He, Xiaobin Gu, Yue Xie, Guangneng Peng, Zhijun Zhong
Summary: The study investigated antibiotic resistance, emerging environmental pollutants ARGs, and integrons in 995 E. coli isolates obtained from captive non-human primates of 13 zoos in China. Results showed high levels of antibiotic resistance and the presence of multiple drug resistances in the isolates, with tetracycline, beta-lactams, and sulfonamide resistance being most common. Integrons were found to be strongly associated with certain antibiotics, highlighting the need for preventive measures to curb the spread of integron-mediated ARGs.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Editorial Material
Microbiology
Alfredo G. Torres
Summary: The Latin American Coalition for Escherichia coli Research (LACER) is a network of investigators using One Health approaches to study infections caused by E. coli isolates in the Latin American region, with a focus on the evolution of antibiotic-resistant strains (resistome) and strains with different virulence profiles (virulome). A recent study by Brazilian investigators published in Microbiology Spectrum has revealed the convergence of a wide resistome and virulome over a 45-year period, resulting in the emergence and persistence of high-risk clones affecting humans, animals, and the environment. The rapid dissemination of these strains poses an unattended international threat.
MICROBIOLOGY SPECTRUM
(2022)
Article
Environmental Sciences
Laurice Beatrice Raphaelle O. dela Pena, Mae Ashley G. Nacario, Nicole R. Bolo, Windell L. Rivera
Summary: This study detected multidrug-resistant Escherichia coli in samples collected around Laguna Lake in the Philippines and identified fecal and sewage sources as potential reservoirs of antibiotic-resistant bacteria. The results emphasize the importance of responsible antibiotic usage to mitigate the spread of antibiotic resistance.