Article
Multidisciplinary Sciences
An-Ni Zhang, Jeffry M. Gaston, Chengzhen L. Dai, Shijie Zhao, Mathilde Poyet, Mathieu Groussin, Xiaole Yin, Li-Guan Li, Mark C. M. van Loosdrecht, Edward Topp, Michael R. Gillings, William P. Hanage, James M. Tiedje, Katya Moniz, Eric J. Alm, Tong Zhang
Summary: Antibiotic resistance genes are common among bacteria, but not all pose high risks to human health. Researchers have developed an omics-based framework to rank these genes by risk, taking into account their enrichment in human associated environments, gene mobility, and host pathogenicity.
NATURE COMMUNICATIONS
(2021)
Article
Microbiology
Yan Zhang, Xu Kuang, Juan Liu, Ruan-Yang Sun, Xing-Ping Li, Jian Sun, Xiao-Ping Liao, Ya-Hong Liu, Yang Yu
Summary: The study revealed the prevalence of mcr-1-positive Escherichia coli in migratory birds from Guangdong, China, highlighting their role in the transmission of antibiotic resistance. The bacteria exhibited diverse sequence types and were phylogenetically related to strains from other sources in China, emphasizing the significance of migratory birds as potential transmitters of antibiotic resistance.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Infectious Diseases
Md Bashir Uddin, Mohammad Nurul Alam, Mahmudul Hasan, S. M. Bayejed Hossain, Mita Debnath, Ruhena Begum, Mohammed A. Samad, Syeda Farjana Hoque, Md. Shahidur Rahman Chowdhury, Md. Mahfujur Rahman, Md. Mukter Hossain, Mohammad Mahmudul Hassan, Ake Lundkvist, Josef D. Jarhult, Mohamed E. El Zowalaty, Syed Sayeem Uddin Ahmed
Summary: This study investigated the antimicrobial resistance and presence of the mcr-1 gene in E. coli isolates from chicken feces in Bangladesh. The isolates showed high resistance to various antibiotics, including colistin. The study confirmed the presence of the eaeA gene and mcr-1 gene in the isolates, and identified a similarity between colistin-resistant genes. The findings highlight the necessity of implementing strict measures to reduce the imprudent use of antibiotics in agriculture and poultry farming.
Article
Infectious Diseases
Elsa de la Cadena, Mateo Mahecha, Ana Maria Velandia, Juan Carlos Garcia-Betancur, Laura J. J. Rojas, Jessica Porras, Christian Pallares, Maria Virginia Villegas
Summary: We discovered the presence of the mcr-1 gene in a low percentage of colistin-resistant Escherichia coli isolates from Colombian hospitals. Whole genome sequencing revealed the presence of multiple resistance genes and different sequence types in the five isolates carrying mcr-1. The spread of mcr-1 in E. coli in this geographic region seems to be limited and has not affected high-risk clones like ST131.
Article
Microbiology
Ping Cheng, Yuqi Yang, Sai Cao, Haibin Liu, Xiaoting Li, Jichao Sun, Fulei Li, Muhammad Ishfaq, Xiuying Zhang
Summary: The study found a high prevalence of mcr-1-positive colistin-resistant E. coli in food animals, showing extensive antimicrobial resistance, strong transferability, and impact on host fitness.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Infectious Diseases
Xiaoman Yang, Rundong Shu, Leqi Hou, Panpan Ren, Xin Lu, Zhi Huang, Zengtao Zhong, Hui Wang
Summary: This study found that the mcr gene inhibits the transfer of colistin resistance-related plasmids, but this inhibitory effect is reversed in the intestine. Certain factors in the gut can enhance the transfer frequency of mcr-containing plasmids. These findings are important for understanding the risk of colistin resistance transmission and for controlling its spread.
Article
Immunology
Qiaoling Li, Changrui Qian, Xueya Zhang, Tingting Zhu, Weina Shi, Mengdi Gao, Chunlin Feng, Ming Xu, Hailong Lin, Li Lin, Junwan Lu, Xi Lin, Kewei Li, Teng Xu, Qiyu Bao, Changchong Li, Hailin Zhang
Summary: This study investigated the colistin resistance mechanism of clinical E. coli isolates using the agar dilution method, polymerase chain reaction, and comparative genomic analysis. The results showed an increase in colistin resistance in E. coli isolates in 2019 compared to previous years. The study also identified six isolates carrying the mcr-1 gene, including a novel variant with a mutation.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
William Calero-Caceres, Kerly Rodriguez, Anabell Medina, Jennifer Medina, Nimer Ortuno-Gutierrez, Temmy Sunyoto, Cicero Armidio Gomes Dias, Carlos Bastidas-Caldes, Maria Soledad Ramirez, Anthony David Harries
Summary: The One Health concept is crucial in addressing the challenge of multidrug-resistant bacteria in both human and animal health. The discovery of the plasmid-borne mcr gene poses a significant threat, and the World Health Organization recommends surveillance strategies to control its spread. The analysis of E. coli genomes carrying mcr-1 reveals patterns in virulence genes, plasmid content, and antibiotic resistance, highlighting the importance of environmental monitoring in understanding antimicrobial resistance origins and dissemination.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Veterinary Sciences
Prasert Apiwatsiri, Pawiya Pupa, Jitrapa Yindee, Waree Niyomtham, Wandee Sirichokchatchawan, Kittitat Lugsomya, Asad Ali Shah, Nuvee Prapasarakul
Summary: By investigating the effects of Thai LAB strains on colistin-resistant E. coli, it was found that the CFS of these strains significantly reduced the transfer frequency of resistance gene mcr-1 and inhibited the formation of biofilms. The application of Thai LAB strains may be an attractive alternative to antibiotics for reducing biofilm formation and limiting the spread of antibiotic-resistant genes.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Food Science & Technology
Wei Li, Yanfei Yan, Jia Chen, Ruiwen Sun, Yuxuan Wang, Tingfen Wang, Zitian Feng, Kai Peng, Juan Wang, Sheng Chen, Yanping Luo, Ruichao Li, Baowei Yang
Summary: In China, mcr-1 gene was found in both foodborne and clinical strains of Escherichia coli and Salmonella, indicating successful transfer of colistin resistance between the two bacteria. Different types of plasmids (IncI2, IncX4, and IncHI2) were identified carrying the mcr-1 gene, suggesting horizontal transfer of mcr-1 gene cassette through conjugation between wild-type bacteria. Furthermore, a new mcr-1 gene cassette was discovered, providing evidence for co-transfer of mcr-1 with other antibiotic resistance genes.
Article
Public, Environmental & Occupational Health
Jialiang Mai, Zhuwei Liang, Zhile Xiong, Chao Zhang, Hao Cai, Shuwen Yao, Xiantang Chen, Bingshao Liang, Fei Gao, Zhuohong Huang, Fangjun Lan, Shuyan Liu, Zhenwen Zhou
Summary: The study investigated the sequence type and prevalence of Escherichia coli (E. coli) harboring the mcr-1 gene in the gut flora of children in southern China. The results showed that the mcr-1 gene can be horizontally transmitted within species, highlighting the importance of monitoring bacteria that carry the mcr-1 gene in children.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2023)
Review
Infectious Diseases
Masoud Dadashi, Fatemeh Sameni, Nazila Bostanshirin, Somayeh Yaslianifard, Nafiseh Khosravi-Dehaghi, Mohammad Javad Nasiri, Mehdi Goudarzi, Ali Hashemi, Bahareh Hajikhani
Summary: A systematic review study on the global prevalence and distribution of colistin resistance genes among human clinical isolates of Escherichia coli found that the recent widespread dissemination of E. coli strains harboring mcr genes conferring colistin resistance, especially in Asia and Europe, is concerning and requires more attention.
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE
(2022)
Article
Microbiology
Gordan Kompes, Sanja Duvnjak, Irena Reil, Rene S. Hendriksen, Lauge Holm Sorensen, Maja Zdelar-Tuk, Boris Habrun, Luka Cvetnic, Antonela Bagaric, Silvio Spicic
Summary: In 2021, a multi-drug resistant E. coli strain with the mcr-1 gene was isolated from pig in Croatia. The isolate showed resistance to multiple antimicrobial classes and harbored various resistance genes and virulence genes. The mcr-1 gene was located within a conjugative plasmid, highlighting the importance of identifying mcr-1-carrying E. coli isolates in Croatia, especially in food-producing animals.
Article
Infectious Diseases
Guerrino Macori, Scott Nguyen, Ankita Naithani, Daniel Hurley, Li Bai, Farid El Garch, Frederique Woehrle, Christine Miossec, Benjamin Roques, Peadar O'Gaora, James L. Bono, Seamus Fanning
Summary: This study revealed a diverse population structure of Escherichia coli isolated from bovine faeces and milk samples, showing no specific correlation between phylogroups and pathotypes. The antimicrobial resistance of isolates was confirmed phenotypically, with genomic predictions successfully identifying resistance to colistin. Genetic analysis of four isolates found complex plasmids encoding both antibiotic resistant and virulence genes, including the mcr-1 resistance determinant. These findings provide early evidence of mcr-1 presence in Europe and highlight the diversity of resistance elements in E. coli strains associated with bovine diseases.
Article
Infectious Diseases
Nicholas M. Smith, Arthur Chan, Thomas D. Nguyen, Jacob T. Dumbleton
Summary: The emergence of mobile colistin resistance (mcr)-mediated polymyxin resistance has significantly reduced the effectiveness of polymyxins in clinical use. This study found that both selective pressure and underlying polymyxin resistance contribute to bacterial regrowth, despite treatment with high concentration of polymyxin B. The results suggest that even with a low proportion of mcr-1-harboring cells, selective pressure from pharmacokinetic-optimized polymyxin B regimen can still lead to regrowth and selection of polymyxin-resistant cells.
Article
Immunology
Edgar Gonzalez-Villalobos, Rosa Maria Ribas-Aparicio, Laura Belmont-Monroy, Gerardo Aparicio-Ozores, H. Angel Manjarrez-Hernandez, Sandra Gavilanes-Parra, Jose Luis Balcazar, Jose Molina-Lopez
Summary: This study found that class 1 integrons are widely distributed among multidrug-resistant uropathogenic Escherichia coli in Mexico, and they may contribute to the selection of multidrug-resistant strains.
MICROBIAL PATHOGENESIS
(2022)
Article
Ecology
Carlos Omar Lomeli-Ortega, Diana R. Barajas-Sandoval, Juan Manuel Martinez-Villalobos, Carmen Rodriguez Jaramillo, Eulalia Meza Chavez, Bruno Gomez-Gil, Jose L. Balcazar, Eduardo Quiroz-Guzman
Summary: This study tested the protective effects of a phage cocktail composed of vB_Vc_SrVc2 and vB_Vc_SrVc9 in shrimp aquaculture. The results showed that the phage cocktail effectively reduced Vibrio species and led to positive changes in shrimp postlarvae.
Article
Fisheries
Miray Etyemez Buyukdeveci, Ibrahim Cengizler, Jose L. Balcazar, Ibrahim Demirkale
Summary: Feeding two strains of Bacillus bacteria has positive effects on the growth performance, intestinal morphology, immunity, and disease resistance in Nile tilapia.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2023)
Review
Microbiology
Mingming Sun, Shujian Yuan, Rong Xia, Mao Ye, Jose Luis Balcazar
Summary: Bacterial viruses are abundant in soil ecosystems, and recent advancements in metagenomics and viromics have identified a diverse range of virus-encoded auxiliary metabolic genes (AMGs) in soils. These AMGs play important roles in transforming carbon, phosphorus, and sulfur, degrading organic pollutants, and resisting antibiotics. Viral AMGs can influence soil biogeochemical processes by interfering with bacterial host metabolism, and they contribute to the adaptation of bacterial hosts in stressed soil environments. This mini-review summarizes the diversity and function of virus-encoded AMGs in the soil environment, with a focus on the evolutionary significance of AMGs involved in virus-host interactions. It also highlights the current gaps and future perspectives for research on viral AMGs in soils.
ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Environmental Sciences
Meritxell Gros, Josep Mas-Pla, Alexandre Sanchez-Melsio, Mira Celic, Marc Castano, Sara Rodriguez-Mozaz, Carles M. Borrego, Jose Luis Balcazar, Mira Petrovic
Summary: This study investigates the occurrence, transport, and risks associated with antibiotic residues, antibiotic resistance genes, and antibiotic resistant Escherichia coli in natural springs in an agroecosystem environment. The results show that tetracycline and sulfonamide residues are the most commonly found, and genes conferring resistance to sulfonamides and tetracyclines are present in most springs. Antibiotic resistant E. coli is also detected, but with poor correlations to the concentrations of antibiotic residues and genes. The occurrence of antibiotics, genes, and bacteria is influenced by seasonal variations, hydrological factors, and reactive transport processes. The risk assessment suggests a low risk for both groundwater environment and human health when spring water is used for direct consumption.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Microbiology
William Calero-Caceres, Kerly Rodriguez, Anabell Medina, Jennifer Medina, Nimer Ortuno-Gutierrez, Temmy Sunyoto, Cicero Armidio Gomes Dias, Carlos Bastidas-Caldes, Maria Soledad Ramirez, Anthony David Harries
Summary: The One Health concept is crucial in addressing the challenge of multidrug-resistant bacteria in both human and animal health. The discovery of the plasmid-borne mcr gene poses a significant threat, and the World Health Organization recommends surveillance strategies to control its spread. The analysis of E. coli genomes carrying mcr-1 reveals patterns in virulence genes, plasmid content, and antibiotic resistance, highlighting the importance of environmental monitoring in understanding antimicrobial resistance origins and dissemination.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Shujian Yuan, Ville-Petri Friman, Jose Luis Balcazar, Xiaoxuan Zheng, Mao Ye, Mingming Sun, Feng Hu
Summary: This study investigated the assembly processes of bacterial and viral communities in clean and OCP-contaminated soils in China. The results showed that assembly of bacterial taxa and genes was dominated by a deterministic process, while assembly of viral taxa and AMGs was driven by a stochastic process. Additionally, viruses showed promise for the dissemination of functional genes among bacterial communities in OCP-contaminated soil.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Environmental Sciences
Victoria Osorio, Arnau Sabater i Mezquita, Jose Luis Balcazar
Summary: Antibiotic misuse in livestock poses a significant threat to human health due to the development of antibiotic resistance in bacteria. Through comparative analysis of faecal metagenomes from swine, poultry, cattle, and humans, we found that poultry manure had a higher prevalence of antibiotic resistance genes compared to other species. Clinically relevant resistance genes, including mcr-1 and blaCTX-M, were detected across all species. Poultry manure was identified as a hotspot for multidrug resistance, highlighting the urgent need for action in the livestock industry to combat antibiotic resistance.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Oriol Casabella-Font, Soraya Zahedi, Jose Luis Balcazar, Jelena Radjenovic, Maite Pijuan
Summary: The impact of graphene oxide on the anaerobic digestion of waste activated sludge was examined using biochemical methane potential tests at two different concentrations. Graphene oxide addition enhanced the removal of various pharmaceuticals, including those that are biological degradation persistent. However, high concentrations of graphene oxide partially inhibited methane production. The relative abundance of antibiotic resistance genes was unaffected, but there were significant changes in the microbial community.
ENVIRONMENTAL POLLUTION
(2023)
Article
Ecology
Rong Xia, Mingming Sun, Jose Luis Balcazar, Pingfeng Yu, Feng Hu, Pedro J. J. Alvarez
Summary: This study investigated the interactions between earthworm intestinal phages and their bacteria under different benzo[a]pyrene (BaP) concentrations using metagenomics and metatranscriptomics. The results showed that low-level BaP stress stimulated microbial metabolism and enhanced the antiphage defense system, while high-level BaP exposure disrupted microbial metabolism and suppressed the antiphage systems. Overall, these findings expand our knowledge of complex phage-bacterium interactions in pollution-stressed worm guts and deepen our understanding of the ecological and evolutionary roles of phages.
Editorial Material
Microbiology
Jorge Olivares-Pacheco, Elisabet Marti, Lorena Rodriguez-Rubio, William Calero-Caceres
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Rose Chinly Mae H. Ortega, Sharon Rose M. Tabugo, Joey Genevieve T. Martinez, Chinee S. Padasas, Jose L. Balcazar
Summary: This study assessed the bacterial community structure in the skin of Barbour's seahorses, with a focus on the Aeromonadaceae family. The presence of Aeromonas genus in the seahorses' skin and its relationship with the surrounding sediment were analyzed. The findings provide baseline information for future research on the role of Aeromonas species in seahorse microbiota and health. Importance rating: 7 out of 10.
Article
Infectious Diseases
Carlos Bastidas-Caldes, Emily Cisneros-Vasquez, Antonella Zambrano, Andrea Mosquera-Maza, William Calero-Caceres, Joaquin Rey, Yoshimasa Yamamoto, Mayumi Yamamoto, Manuel Calvopina, Jacobus H. de Waard
Summary: This study aimed to determine the coexistence of extended-spectrum beta-lactamase (ESBL) and carbapenemase genes in Escherichia coli and Klebsiella pneumoniae strains carrying the mcr-1 gene in rural communities in Ecuador. The majority of the mcr-1 isolates harbored at least one beta-lactam resistance gene, with TEM-bla and SHV-bla genes being the most prevalent. The multi-locus sequencing typing (MLST) analysis revealed the presence of unique sequence types (ST) that have not been described in humans and animals before. This coexistence of mcr-1 and beta-lactam resistant genes highlights the potential threat to the effectiveness of last-resort antibiotics and the role of backyard animals as a reservoir.
Editorial Material
Infectious Diseases
William Calero-Caceres, Jose Luis Balcazar
Article
Social Issues
Camila Montesinos-Guevara, Paula Zambrano-Achig, Maria Jose Masson, Andres Viteri-Garcia, Emmanuelle Quentin
Summary: There is an increasing recognition of women's representation at work, but there is still a gender gap in science that needs to be closed. Women face a glass ceiling in science beyond graduate level due to gender-specific patterns. Men are more likely to hold prestigious authorship positions, resulting in a less linear career path for women. The aim of this study is to analyze the gender composition of systematic reviews published in the last two years in the most recognized health database.
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
