The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations

The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex

(2018) Miguel Mompeán et al.   CELL

Transport-Relevant Protein Conformational Dynamics and Water Dynamics on Multiple Time Scales in an Archetypal Proton Channel: Insights from Solid-State NMR

(2018) Venkata S. Mandala et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient 15N–13C Polarization Transfer by Third-Spin-Assisted Pulsed Cross-Polarization Magic-Angle-Spinning NMR for Protein Structure Determination

(2018) Martin D. Gelenter et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structure of the glucagon receptor in complex with a glucagon analogue

(2018) Haonan Zhang et al.   NATURE

Nanotubes, Plates, and Needles: Pathway-Dependent Self-Assembly of Computationally Designed Peptides

(2018) Yu Tian et al.   BIOMACROMOLECULES

Methylammonium lead chloride: A sensitive sample for an accurate NMR thermometer

(2017) Guy M. Bernard et al.   JOURNAL OF MAGNETIC RESONANCE

Water Distribution, Dynamics, and Interactions with Alzheimer’s β-Amyloid Fibrils Investigated by Solid-State NMR

(2017) Tuo Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cryo-EM structures of tau filaments from Alzheimer’s disease

(2017) Anthony W. P. Fitzpatrick et al.   NATURE

Structural Polymorphism of Alzheimer’s β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study

(2016) Matthew R. Elkins et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils

(2016) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril

(2016) Marielle Aulikki Wälti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Transitions and Interactions in the Early Stages of Human Glucagon Amyloid Fibrillation

(2015) Balakrishnan S. Moorthy et al.   BIOPHYSICAL JOURNAL

Amyloid Polymorphism: Structural Basis and Neurobiological Relevance

(2015) Robert Tycko   NEURON

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

Probing membrane protein structure using water polarization transfer solid-state NMR

(2014) Jonathan K. Williams et al.   JOURNAL OF MAGNETIC RESONANCE

A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia

(2014) Joseph Chabenne et al.   Molecular Metabolism

Efficient resonance assignment of proteins in MAS NMR by simultaneous intra- and inter-residue 3D correlation spectroscopy

(2013) Eugenio Daviso et al.   JOURNAL OF BIOMOLECULAR NMR

Protein backbone and sidechain torsion angles predicted from NMR chemical shifts using artificial neural networks

(2013) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Broadband homonuclear correlation spectroscopy driven by combined R2nv sequences under fast magic angle spinning for NMR structural analysis of organic and biological solids

(2013) Guangjin Hou et al.   JOURNAL OF MAGNETIC RESONANCE

Mechanisms of glucagon degradation at alkaline pH

(2013) Nicholas Caputo et al.   PEPTIDES

Antiparallel  -sheet architecture in Iowa-mutant  -amyloid fibrils

(2012) W. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A thermodynamic analysis of fibrillar polymorphism

(2010) Martin D. Jeppesen et al.   BIOPHYSICAL CHEMISTRY

Glucagon Fibril Polymorphism Reflects Differences in Protofilament Backbone Structure

(2010) Christian Beyschau Andersen et al.   JOURNAL OF MOLECULAR BIOLOGY

The metabolic actions of glucagon revisited

(2010) Kirk M. Habegger et al.   Nature Reviews Endocrinology

A SAXS Study of Glucagon Fibrillation

(2009) Cristiano Luis Pinto Oliveira et al.   JOURNAL OF MOLECULAR BIOLOGY

Early Stages of Amyloid Fibril Formation Studied by Liquid-State NMR: The Peptide Hormone Glucagon

(2008) Anna Sigrid Pii Svane et al.   BIOPHYSICAL JOURNAL

Proton assisted recoupling and protein structure determination

(2008) Gaël De Paëpe et al.   JOURNAL OF CHEMICAL PHYSICS

AFM-based force spectroscopy measurements of mature amyloid fibrils of the peptide glucagon

(2008) Mingdong Dong et al.   NANOTECHNOLOGY

Molecular conformation and dynamics of the Y145Stop variant of human prion protein in amyloid fibrils

(2008) J. J. Helmus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular structural basis for polymorphism in Alzheimer's  -amyloid fibrils

(2008) A. K. Paravastu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid Fibrils of the HET-s(218-289) Prion Form a   Solenoid with a Triangular Hydrophobic Core

(2008) C. Wasmer et al.   SCIENCE

Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles

(2008) S. Hiller et al.   SCIENCE