A Network Involving Gut Microbiota, Circulating Bile Acids, and Hepatic Metabolism Genes That Protects Against Non‐Alcoholic Fatty Liver Disease

Functional Interactions between Gut Microbiota Transplantation, Quercetin, and High-Fat Diet Determine Non-Alcoholic Fatty Liver Disease Development in Germ-Free Mice

(2019) David Porras et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Beneficial effects of exercise on gut microbiota functionality and barrier integrity, and gut-liver crosstalk in an in vivo model of early obesity and non-alcoholic fatty liver disease

(2019) Sara Carbajo-Pescador et al.   Disease Models & Mechanisms

Bile acids, microbiota and metabolism

(2018) Sarah A. Taylor et al.   HEPATOLOGY

Liver X receptors in lipid signalling and membrane homeostasis

(2018) Bo Wang et al.   Nature Reviews Endocrinology

Dysbiosis of the salivary microbiota in pediatric-onset primary sclerosing cholangitis and its potential as a biomarker

(2018) Kentaro Iwasawa et al.   Scientific Reports

Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high fat diet-fed mice

(2018) Jie Yin et al.   JOURNAL OF PINEAL RESEARCH

Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids

(2018) Keita Watanabe et al.   PLoS One

The gut microbiota drives the impact of bile acids and fat source in diet on mouse metabolism

(2018) Sarah Just et al.   Microbiome

Interaction of gut microbiota with dysregulation of bile acids in the pathogenesis of nonalcoholic fatty liver disease and potential therapeutic implications of probiotics

(2018) Jiezhong Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Intestinal Microbiota Modulation in Obesity-Related Non-alcoholic Fatty Liver Disease

(2018) David Porras et al.   Frontiers in Physiology

Probiotics improve gut microbiota dysbiosis in obese mice fed a high-fat or high-sucrose diet

(2018) Cheng Kong et al.   NUTRITION

Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut-liver axis activation

(2017) David Porras et al.   FREE RADICAL BIOLOGY AND MEDICINE

Changes in the Prevalence of Hepatitis C Virus Infection, Nonalcoholic Steatohepatitis, and Alcoholic Liver Disease Among Patients With Cirrhosis or Liver Failure on the Waitlist for Liver Transplantation

(2017) David Goldberg et al.   GASTROENTEROLOGY

Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

(2017) Oscar Chávez-Talavera et al.   GASTROENTEROLOGY

Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD

(2017) Na Jiao et al.   GUT

The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases

(2017) Naga Chalasani et al.   HEPATOLOGY

The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids

(2017) Puneet Puri et al.   HEPATOLOGY

Lactobacillus fermentum FTDC 8312 combats hypercholesterolemia via alteration of gut microbiota

(2017) Huey-Shi Lye et al.   JOURNAL OF BIOTECHNOLOGY

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Dietary Capsaicin Improves Glucose Homeostasis and Alters the Gut Microbiota in Obese Diabetic ob/ob Mice

(2017) Jun-Xian Song et al.   Frontiers in Physiology

Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism

(2016) Annika Wahlström et al.   Cell Metabolism

Bile acids and nonalcoholic fatty liver disease: Molecular insights and therapeutic perspectives

(2016) Juan P. Arab et al.   HEPATOLOGY

Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta-omics-based approach

(2016) Federica Del Chierico et al.   HEPATOLOGY

Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes

(2016) Zobair M. Younossi et al.   HEPATOLOGY

The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota

(2016) Jérôme Boursier et al.   HEPATOLOGY

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2016) Elena Buzzetti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease

(2016) Marialena Mouzaki et al.   PLoS One

The intrahepatic expression levels of bile acid transporters are inversely correlated with the histological progression of nonalcoholic fatty liver disease

(2015) Kazuya Okushin et al.   JOURNAL OF GASTROENTEROLOGY

Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease

(2015) Sandra Pisonero-Vaquero et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Interactions between the intestinal microbiota and bile acids in gallstones patients

(2015) Nirit Keren et al.   Environmental Microbiology Reports

Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota

(2015) Chih-Jung Chang et al.   Nature Communications

Bile acids and the gut microbiome

(2014) Jason M. Ridlon et al.   CURRENT OPINION IN GASTROENTEROLOGY

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Finding the balance: The role ofS-adenosylmethionine and phosphatidylcholine metabolism in development of nonalcoholic fatty liver disease

(2013) René L. Jacobs et al.   HEPATOLOGY

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

(2013) Yuki Kawano et al.   JOURNAL OF GASTROENTEROLOGY

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism

(2013) X. Hu et al.   JOURNAL OF INTERNAL MEDICINE

Increased Expression of Enzymes of Triglyceride Synthesis Is Essential for the Development of Hepatic Steatosis

(2013) Jingling Jin et al.   Cell Reports

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice

(2012) Tiphaine Le Roy et al.   GUT

Specific bile acids inhibit hepatic fatty acid uptake in mice

(2012) Biao Nie et al.   HEPATOLOGY

Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method

(2012) Juan C. García-Cañaveras et al.   JOURNAL OF LIPID RESEARCH

Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

(2011) M. E. Miquilena-Colina et al.   GUT

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Plasma metabolomic profile in nonalcoholic fatty liver disease

(2010) Satish C. Kalhan et al.   METABOLISM-CLINICAL AND EXPERIMENTAL