Article
Engineering, Manufacturing
Safoura Ahmadzadeh, Ali Ubeyitogullari
Summary: The goal of this study was to enhance the stability of lutein by encapsulating it into starch-ethyl cellulose gels using 3D printing. The effects of various factors, including layer height, EC and starch concentrations, and printing temperature, were investigated. The optimized conditions resulted in significantly higher lutein retention and improved stability.
ADDITIVE MANUFACTURING
(2023)
Article
Food Science & Technology
Jialong Li, Cuicui Zeng, Qiqi Huang, Ming-Ming Zheng, Jing Chen, Da Ma
Summary: To overcome the limitations of alpha-mangostin, researchers fabricated hydrogels loaded with alpha-mangostin using alginate/xanthan gum or alginate/kappa-carrageenan. By increasing the concentration of polysaccharides, the release of alpha-mangostin was slowed down. The hydrogels containing xanthan gum and kappa-carrageenan showed faster release of alpha-mangostin.
Article
Biochemistry & Molecular Biology
Azarmidokht Gholamipour-Shirazi, Ian T. Norton, Tom Mills
Summary: A dual temperature and electro responsive kappa- and iota-carrageenan based hydrogel formulation was developed for efficient food material and drug delivery, showing high drug loading and sustained release. This formulation does not rely on 3D printing, but can contribute to feedstocks for 3D printing in the food and pharmaceutical industries, potentially enabling the creation of more complex smart structures and tuning release behavior in the future.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Computer Science, Interdisciplinary Applications
Saban Ozturk, Umut Ozkaya
Summary: The study suggests an AI method using convolutional neural network architecture for classifying gastrointestinal tract image datasets, showing that a shallowly trained CNN architecture needs a strong classifier to robustly classify unbalanced datasets.
JOURNAL OF BIOMEDICAL INFORMATICS
(2021)
Review
Chemistry, Multidisciplinary
Anas Aljabbari, Shinji Kihara, Thomas Rades, Ben J. Boyd
Summary: While the formation of a biomolecular corona on particles in plasma is well understood, little is known about the formation and composition of the corona on particles within the gastrointestinal tract. This review aims to establish the significance of the formation of a gastrointestinal corona in oral drug delivery and provide new avenues for controlling the behavior of orally administered pharmaceuticals.
JOURNAL OF CONTROLLED RELEASE
(2023)
Review
Pharmacology & Pharmacy
Lijun Cai, Yu Wang, Zhiqiang Luo, Jinglin Wang, Haozhen Ren, Yuanjin Zhao
Summary: This review summarizes the development of self-triggered micro-/milli-devices (STMDs) for delivery via the gastrointestinal tract. It highlights the morphological characteristics and functional design of STMDs, and explores their working mechanisms in the gastrointestinal tract. Despite progress, there are still limitations that need to be addressed through further research and development.
EXPERT OPINION ON DRUG DELIVERY
(2023)
Review
Chemistry, Medicinal
Konstantina Iliou, Stefanos Kikionis, Efstathia Ioannou, Vassilios Roussis
Summary: Marine biopolymer-based electrospun nanofibrous scaffolds show great potential for applications in biomedical fields, such as tissue engineering, drug delivery, and wound healing, due to their multifunctional characteristics and tunable mechanical properties.
Article
Chemistry, Medicinal
Bruno Pessoa, Mar Collado-Gonzalez, Giuseppina Sandri, Antonio Ribeiro
Summary: This study aimed to optimize a nanoparticle formulation for orally delivered insulin by assessing the relationship between design parameters and experimental data using response surface methodology. The results showed that a nanoparticle formulation with 0.03% PEG, 0.047% chitosan, and 1.20% albumin provided an optimal solution for insulin oral delivery, maintaining insulin bioactivity in simulated intestinal media.
Review
Biochemistry & Molecular Biology
Christian Galasso, Nadia Ruocco, Mirko Mutalipassi, Lucia Barra, Valentina Costa, Chiara Giommi, Alessia Dinoi, Martina Genovese, Daniela Pica, Chiara Romano, Silvestro Greco, Chiara Pennesi
Summary: Marine environments provide a valuable source of biopolymers with potential biomedical applications, especially in drug delivery. Marine polymers possess unique biochemical properties that enable efficient drug binding and controlled release in target tissues. However, current research is still in its early stages, and more attention needs to be focused on sustainable production of marine polymers and product development.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Multidisciplinary
Jaebum Park, Michael J. McShane
Summary: Nanoscale bio-polymer coatings play a crucial role in medical device applications, and chemically crosslinking can reduce the diffusivity of glucose, effectively controlling the permeation of small molecules and enhancing biomimetic properties.
Review
Biotechnology & Applied Microbiology
Deepak A. Subramanian, Robert Langer, Giovanni Traverso
Summary: Oral delivery is the preferred route for drug administration, but rapid clearance of drugs from the gastrointestinal tract is a major barrier. Researchers have explored the use of GI mucus to improve drug delivery efficacy. This review discusses the properties and function of GI mucus, as well as different types of mucus-interacting drug delivery systems. FDA-approved systems in each category are also reviewed.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Review
Pharmacology & Pharmacy
Ehsan Kaffash, Mohammad-Ali Shahbazi, Hooman Hatami, Ali Nokhodchi
Summary: Oral delivery is the preferred method of drug administration, but it faces challenges in the absorption of therapeutic macromolecules such as peptides. This review highlights recent physical methods, including microneedle injections and magnetic drug targeting, that show promise in improving the oral bioavailability of these macromolecules. The potential and challenges of these new technologies are discussed, as they may have an impact on future approaches used by pharmaceutical companies.
DRUG DISCOVERY TODAY
(2022)
Article
Environmental Sciences
Norhazwani Jaafar, Ahmad Azfaralariff, Syafiq M. Musa, Mazlan Mohamed, Abdul Hafidz Yusoff, Azwan Mat Lazim
Summary: The study found a widespread distribution of microplastics in commercial marine fishes from Malaysia waters, which could potentially lead to human exposure through fish consumption.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Medicine, General & Internal
Ah Young Yoo, Moon Kyung Joo, Jong-Jae Park, Beom Jae Lee, Seung Han Kim, Won Shik Kim, Hoon Jai Chun
Summary: Among patients undergoing dual antiplatelet therapy, some may experience recurrent upper gastrointestinal bleeding. These patients are predominantly male, with bleeding mainly from the stomach and peptic ulcers. Age is an important factor for re-bleeding, all-cause mortality, and re-bleeding-related mortality.
Article
Chemistry, Applied
Huong Thi Hoang, Sung-Han Jo, Quoc-Thang Phan, Hansol Park, Sang-Hyug Park, Chul-Woong Oh, Kwon Taek Lim
Summary: A dual pH-/thermo-responsive hydrogel was successfully designed using a polyelectrolyte complex and chemical crosslinking, demonstrating high drug loading capacity and controlled drug release properties at different pH levels, showing promising applications in colon-targeted drug delivery systems.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Bassant Yousry Eweida, Ahmed Mohamed Omer, Tamer Mahmoud Tamer, Hesham Abd-Elfatah Mohamed Soliman, Ahmed Amin Zaatot, Mohamed Samir Mohy-Eldin
Summary: A novel Chitosan-g-Octanal Schiff base adsorbent, synthesized through click chemistry, showed excellent performance in the removal of heavy crude oil spills compared to native Chitosan adsorbent, with higher oil adsorption percentages and faster adsorption rates. The adsorption process followed the pseudo-second order model and fitted well with the Langmuir model, indicating it to be an endothermic, favorable, and spontaneous process.
Review
Chemistry, Multidisciplinary
Eman M. Abd El-Monaem, Abdelazeem S. Eltaweil, Hala M. Elshishini, Mohamed Hosny, Mohamed M. Abou Alsoaud, Nour F. Attia, Gehan M. El-Subruiti, Ahmed M. Omer
Summary: This article provides a comprehensive overview of recent research on the removal of antibiotics by chitosan composite-based adsorbents. The structure, optimal removal conditions, and adsorption mechanisms of various antibiotics are summarized. The development of chitosan composite-based adsorbents and the factors influencing the adsorption process are discussed. Conclusions and future recommendations are also provided.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Physical
Eman M. Abd El-Monaem, Ahmed M. Omer, Randa E. Khalifa, Abdelazeem S. Eltaweil
Summary: In this study, a floated bead composite was fabricated for the efficient removal of tetracycline from water bodies. The composite beads exhibited a large specific surface area, good adsorption performance with a relatively short equilibrium time, and easy separation. Moreover, the composite beads showed promising applicability as a reusable adsorbent for the efficient removal of antibiotics.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Applied
Tamer E. Elmetwaly, Sawsan S. Darwish, Nour F. Attia, Rushdya R. A. Hassan, Amal A. El Ebissy, Abdelazeem S. Eltaweil, Ahmed M. Omer, Hesham R. El-Seedi, Sally E. A. Elashery
Summary: A new and innovative conservative coating was developed for historical paper consolidation, using cellulose nanocrystals and inorganic halloysite nanotubes. This transparent coating significantly improved the tensile strength, thermal stability, and UV protection ability of the consolidated historic paper, while maintaining its optical properties.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Multidisciplinary Sciences
Mohamed M. Abou Alsoaud, Mahmoud A. Taher, Abdelrahman M. Hamed, Mohamed S. Elnouby, Ahmed M. Omer
Summary: In this study, Kaolin (K) impregnated aminated chitosan (AM-CTS) composite beads were fabricated and used for the adsorption of anionic Congo red (CR) dye. The results showed that the K@AM-CTS composite beads had a larger specific surface area and improved thermal stability compared to pure AM-CTS. The adsorption equilibrium of CR dye was achieved rapidly and the removal efficiency increased with increasing kaolin content. The adsorption process followed the pseudo-first order kinetic model and the Freundlich isotherm model, and was determined to be physical adsorption with spontaneous and endothermic nature. The developed K@AM-CTS composites beads demonstrated good reusability.
SCIENTIFIC REPORTS
(2022)
Article
Pharmacology & Pharmacy
Haozhan Feng, Minlan Li, Zifeng Xing, Xiao-kun Ouyang, Junhong Ling
Summary: Fucoxanthin, a natural carotenoid pigment found in brown seaweed, has shown antitumor activity. However, its effectiveness as a therapeutic agent is limited due to low bioavailability, poor water solubility, and poor physicochemical stability. In this study, a targeted magnetic, acid-labile nano-carrier was designed and constructed to improve the bioactivity of Fucoxanthin based on the acidic nature of the tumor microenvironment. The nano-carrier exhibited sustained and pH-dependent drug release, leading to improved stability and bioavailability of Fucoxanthin.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Physical
Guo Yi, Junhong Ling, Yongjun Jiang, YuQing Lu, Li-Ye Yang, Xiao-kun Ouyang
Summary: In this study, pH-sensitive chito-oligosaccharide nano-drug-loaded particles were developed with good bio-compatibility, biodegradation, and controlled drug delivery. The nanoparticles demonstrated site targeting under weak acidic tumor conditions, improved drug efficacy, and reduced toxic side effects.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Applied
Abdelazeem S. Eltaweil, Eman M. Abd El-Monaem, Gehan M. El-Subruiti, Bassma M. Ali, Mona M. Abd El-Latif, Ahmed M. Omer
Summary: New porous adsorbent beads were developed by incorporating graphene oxide (GO) into cellulose acetate beads (CA) for the removal of methylene blue (MB) dye. The adsorption of MB dye increased with increasing GO ratio, following the PSO kinetic model and Langmuir isotherm model. The maximum adsorption capacity reached 369.85 mg/g. The adsorption mechanism involved electrostatic interactions, H-bonding, van der Waals forces, n-pi and pi-pi interactions. The beads exhibited excellent recycling ability and high selectivity towards MB molecules in the presence of co-existing cations.
JOURNAL OF POROUS MATERIALS
(2023)
Article
Environmental Sciences
Nehad. A. A. Elmaghraby, Ahmed. M. M. Omer, El-Refaie Kenawy, Mohamed Gaber, Safaa Ragab, Ahmed El Nemr
Summary: This study successfully fabricated a nanofiber composite of cellulose acetate/activated carbon (CA/AC) using the electrospinning technique. The CA/AC nanofiber composite demonstrated a high oil adsorption capacity and stability. The incorporation of activated carbon into the nanofiber mats improved the oil adsorption capacity, and the composite material showed consistent adsorption performance even after multiple recycling.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Yuhong Tian, Yongjun Jiang, Zhengshun Wen, Liping Guan, Xiaokun Ouyang, Wanjing Ding, Zhongjun Ma
Summary: Lipid-lowering is an effective method for preventing and treating cardiovascular diseases, and developing safe and effective novel lipid-lowering drugs is of great significance. We discovered that the organic crude extracts of Nocardiopsis sp. ZHD001 exhibited strong lipid-lowering effects in high-fat-diet-fed mice models. Chemical investigations led to the identification of two new sphydrofuran-derived compounds and one known compound. Bioactivity evaluations showed that these compounds exhibited significant lipid-lowering activity with lower cytotoxicity compared to simvastatin. Our results suggest that sphydrofuran-derived compounds may be promising candidates for lipid-lowering drugs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Hongping Xu, Junhong Ling, Han Zhao, Xinyi Xu, Xiao-kun Ouyang, Xiaoyong Song
Summary: Chemotherapy is widely used for tumor treatment, but it causes the death of normal cells due to non-specific drug distribution. This study developed a novel nanocarrier, MPDA-DOX@FU-SS, which can achieve targeted drug release in the tumor microenvironment. The nanocarrier showed significant inhibition of tumor cell growth.
Article
Biochemistry & Molecular Biology
Mengwen Guo, Junhong Ling, Xinyi Xu, Xiaokun Ouyang
Summary: In this study, a simple and effective method for developing a nanotherapeutic agent for chemotherapy combined with photothermal therapy was presented. The agent consisted of mesoporous polydopamine modified by ferric ions and loaded with the anticancer drug doxorubicin, as well as an outer layer coating of hyaluronic acid. The findings showed that the nanotherapeutic agent had enhanced heat generation effect and demonstrated potent cytotoxicity to tumor cells under near-infrared light illumination. This system deserves further investigation as a potential nanotherapeutic platform for photothermal treatment of cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Abdelazeem S. Eltaweil, Maha S. Ahmed, Gehan M. El-Subruiti, Randa E. Khalifa, Ahmed M. Omer
Summary: New composite microbeads composed of carboxylated graphene oxide (CGO) impregnated into alginate (Alg) microbeads and coated with aminated chitosan (AmCs) layer were developed. The microbeads exhibited pH-sensitivity and the concentration of CGO and AmCs greatly influenced their swelling behavior and protection of Alg microbeads. The composite microbeads showed improved drug loading efficiency and sustained release of ciprofloxacin (CIP) compared to Alg microbeads.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Ahmed M. Omer, Abdelazeem S. Eltaweil, Esmail M. El-Fakharany, Eman M. Abd El-Monaem, Magda M. F. Ismail, Mohamed S. Mohy-Eldin, Mohammed S. Ayoup
Summary: This study developed a novel bioactive chitosan Schiff base (CTS-SB) derivative by coupling chitosan (CTS) with 4-((5, 5-dimethyl-3-oxocyclohex-1-en-1-yl) amino) benzene-sulfonamide. The CTS-SB derivative exhibited enhanced antibacterial, anticancer, and antidiabetic activities compared to pure CTS. It showed improved ion exchange capacity, increased antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria, higher inhibitory values of alpha-amylase and alpha-glucosidase, and potential anticancer activity.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Article
Multidisciplinary Sciences
Ahmed M. Omer, Tamer M. Tamer, Mohamed E. Hassan, Randa E. Khalifa, Eman M. Abd El-Monaem, Abdelazeem S. Eltaweil, Mohamed S. Mohy Eldin
Summary: The present study successfully developed an efficient superabsorbent hydrogel for water conservation and slow release of Ethephon. Through analysis and experiments, it was found that the grafted hydrogel made from modified cellulose and hydrophilic monomers has good water absorption capacity and nutrient carrying ability, which can be applied in agricultural production of sandy soil.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
