Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study
出版年份 2019 全文链接
标题
Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study
作者
关键词
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出版物
HYPERTENSION RESEARCH
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-06-26
DOI
10.1038/s41440-019-0270-2
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies
- (2019) Josef Coresh et al. Lancet Diabetes & Endocrinology
- Change in albuminuria as a surrogate endpoint for progression of kidney disease: a meta-analysis of treatment effects in randomised clinical trials
- (2019) Hiddo J L Heerspink et al. Lancet Diabetes & Endocrinology
- Efficacy and safety of esaxerenone (CS-3150) for the treatment of essential hypertension: a phase 2 randomized, placebo-controlled, double-blind study
- (2019) Sadayoshi Ito et al. JOURNAL OF HUMAN HYPERTENSION
- Single- and multiple-dose escalation study to assess pharmacokinetics, pharmacodynamics and safety of oral esaxerenone in healthy Japanese subjects
- (2018) Manabu Kato et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Pathophysiological mechanisms of mineralocorticoid receptor-dependent cardiovascular and chronic kidney disease
- (2018) Akira Nishiyama HYPERTENSION RESEARCH
- Efficiency and specificity of RAAS inhibitors in cardiovascular diseases: how to achieve better end-organ protection?
- (2017) Ali Nehme et al. HYPERTENSION RESEARCH
- High Glucose Stimulates Mineralocorticoid Receptor Transcriptional Activity Through the Protein Kinase C β Signaling
- (2017) Takeshi Hayashi et al. International Heart Journal
- Dose doubling, relative potency, and dose equivalence of potassium-sparing diuretics affecting blood pressure and serum potassium
- (2016) George C. Roush et al. JOURNAL OF HYPERTENSION
- Safety and Antihypertensive Effect of Selara® (Eplerenone): Results from a Postmarketing Surveillance in Japan
- (2016) Shoko Takahashi et al. International Journal of Hypertension
- Effects of Additive Therapy With Spironolactone on Proteinuria in Diabetic Patients Already on ACE Inhibitor or ARB Therapy
- (2016) Mohammad G. Saklayen et al. JOURNAL OF INVESTIGATIVE MEDICINE
- Aldosterone Blockade in CKD: Emphasis on Pharmacology
- (2015) Michael H. Schwenk et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- Anti-albuminuric effects of spironolactone in patients with type 2 diabetic nephropathy: a multicenter, randomized clinical trial
- (2015) Sawako Kato et al. Clinical and Experimental Nephrology
- Albuminuria Is an Appropriate Therapeutic Target in Patients with CKD: The Pro View
- (2015) H. J. Lambers Heerspink et al. Clinical Journal of the American Society of Nephrology
- Spironolactone Add-on for Preventing or Slowing the Progression of Diabetic Nephropathy: A Meta-analysis
- (2015) Jing Hou et al. CLINICAL THERAPEUTICS
- CS-3150, a novel non-steroidal mineralocorticoid receptor antagonist, prevents hypertension and cardiorenal injury in Dahl salt-sensitive hypertensive rats
- (2015) Kiyoshi Arai et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- The renal effects of mineralocorticoid receptor antagonists
- (2015) Stefano Bianchi et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Safety profile of mineralocorticoid receptor antagonists: Spironolactone and eplerenone
- (2015) Mitja Lainscak et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Efficacy and safety of eplerenone in the management of mild to moderate arterial hypertension: Systematic review and meta-analysis
- (2014) Francesco Pelliccia et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Local Mineralocorticoid Receptor Activation and the Role of Rac1 in Obesity-Related Diabetic Kidney Disease
- (2014) Shigetaka Yoshida et al. NEPHRON EXPERIMENTAL NEPHROLOGY
- 2013 ESH/ESC Guidelines for the management of arterial hypertension
- (2013) EUROPEAN HEART JOURNAL
- Nifedipine controlled-release 40 mg b.i.d. in Japanese patients with essential hypertension who responded insufficiently to nifedipine controlled-release 40 mg q.d.: a phase III, randomized, double-blind and parallel-group study
- (2013) Kazuaki Shimamoto et al. HYPERTENSION RESEARCH
- Mineralocorticoid Receptor-Associated Hypertension and Its Organ Damage: Clinical Relevance for Resistant Hypertension
- (2012) H. Shibata et al. AMERICAN JOURNAL OF HYPERTENSION
- Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors
- (2012) Amy McCurley et al. NATURE MEDICINE
- The safety and tolerability of spironolactone in patients with mild to moderate chronic kidney disease
- (2011) Nicola C. Edwards et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure
- (2010) Aurelie Nguyen Dinh Cat et al. FASEB JOURNAL
- Treatment of resistant hypertension
- (2010) Eduardo Pimenta et al. JOURNAL OF HYPERTENSION
- Addition of Angiotensin Receptor Blockade or Mineralocorticoid Antagonism to Maximal Angiotensin-Converting Enzyme Inhibition in Diabetic Nephropathy
- (2009) U. F. Mehdi et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Change in Proteinuria After Adding Aldosterone Blockers to ACE Inhibitors or Angiotensin Receptor Blockers in CKD: A Systematic Review
- (2008) Andrew S. Bomback et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Retrospective Review of the Frequency of ECG Changes in Hyperkalemia
- (2008) B. T. Montague et al. Clinical Journal of the American Society of Nephrology
- Resistant Hypertension: Diagnosis, Evaluation, and Treatment
- (2008) David A. Calhoun et al. HYPERTENSION
- Rapid responses to aldosterone in the kidney and colon
- (2007) Brian J. Harvey et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
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