Mesenchymal stem cells prevent the progression of diabetic nephropathy by improving mitochondrial function in tubular epithelial cells

Ipragliflozin improves mitochondrial abnormalities in renal tubules induced by a high-fat diet

(2018) Susumu Takagi et al.   Journal of Diabetes Investigation

Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain

(2018) Melissa Uil et al.   Scientific Reports

Comparison of Immunological Characteristics of Mesenchymal Stem Cells from the Periodontal Ligament, Umbilical Cord, and Adipose Tissue

(2018) Jin-Hee Kim et al.   Stem Cells International

SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis

(2018) Swayam Prakash Srivastava et al.   Cell Death & Disease

Pharmacologic Approaches to Improve Mitochondrial Function in AKI and CKD

(2017) Hazel H. Szeto   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pyruvate dehydrogenase kinase 4 deficiency attenuates cisplatin-induced acute kidney injury

(2017) Chang Joo Oh et al.   KIDNEY INTERNATIONAL

Metabolic endotoxemia and diabetes mellitus: A systematic review

(2017) Júnia Maria Geraldo Gomes et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Nitric Oxide Produced by Macrophages Inhibits Adipocyte Differentiation and Promotes Profibrogenic Responses in Preadipocytes to Induce Adipose Tissue Fibrosis

(2016) Jung Eun Jang et al.   DIABETES

The role of mitochondrial DNA damage in the development of atherosclerosis

(2016) Emma P.K. Yu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protection of mitochondria prevents high-fat diet–induced glomerulopathy and proximal tubular injury

(2016) Hazel H. Szeto et al.   KIDNEY INTERNATIONAL

Mitochondrial Hormesis and Diabetic Complications: Figure 1

(2015) Kumar Sharma   DIABETES

Bone marrow mononuclear cell transplantation improves mitochondrial bioenergetics in the liver of cholestatic rats

(2015) Daniela Caldas de Andrade et al.   EXPERIMENTAL CELL RESEARCH

11 -HSD1 reduces metabolic efficacy and adiponectin synthesis in hypertrophic adipocytes

(2015) E. H. Koh et al.   JOURNAL OF ENDOCRINOLOGY

Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy

(2015) J. B. Hunt et al.   JOURNAL OF NEUROSCIENCE

Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition

(2015) Sen Shi et al.   KIDNEY INTERNATIONAL

Neural stem cell transplantation enhances mitochondrial biogenesis in a transgenic mouse model of Alzheimer's disease–like pathology

(2015) Wei Zhang et al.   NEUROBIOLOGY OF AGING

Inflammatory Cytokines in Diabetic Nephropathy

(2015) Javier Donate-Correa et al.   Journal of Diabetes Research

The dual role of iNOS in cancer

(2015) Federica Vannini et al.   Redox Biology

Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy: Fact or Fiction?

(2015) Ivonne Loeffler et al.   Cells

Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics

(2014) Wendy S. Hahn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Linagliptin-Mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition in a Therapeutic Regimen

(2014) Keizo Kanasaki et al.   DIABETES

Inflammatory processes in renal fibrosis

(2014) Xiao-Ming Meng et al.   Nature Reviews Nephrology

Evolutionary Roots of Arginase Expression and Regulation

(2014) Jolanta Maria Dzik   Frontiers in Immunology

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

(2014) Meera Rath et al.   Frontiers in Immunology

Secretion of immunoregulatory cytokines by mesenchymal stem cells

(2014) Dobroslav Kyurkchiev   World Journal of Stem Cells

M1 and M2 Macrophages: Oracles of Health and Disease

(2013) Charles Mills   CRITICAL REVIEWS IN IMMUNOLOGY

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy

(2013) L. Xiao et al.   DIABETES

Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism

(2013) Hanning You et al.   KIDNEY INTERNATIONAL

Repeated Systemic Administration of Human Adipose-Derived Stem Cells Attenuates Overt Diabetic Nephropathy in Rats

(2013) Li Zhang et al.   STEM CELLS AND DEVELOPMENT

Human umbilical cord blood-derived mesenchymal stem cells prevent diabetic renal injury through paracrine action

(2012) Jong Hee Park et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK–SIRT1–PGC1α axis in db/db mice

(2012) M. Y. Kim et al.   DIABETOLOGIA

Can We Target Tubular Damage to Prevent Renal Function Decline in Diabetes?

(2012) Joseph V. Bonventre   SEMINARS IN NEPHROLOGY

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

eNOS plays a major role in adiponectin synthesis in adipocytes

(2010) Eun Hee Koh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages and Diabetic Nephropathy

(2010) Greg H. Tesch   SEMINARS IN NEPHROLOGY

Endovenous Administration of Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells Prevents Renal Failure in Diabetic Mice

(2009) Fernando Ezquer et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Serum Lipopolysaccharide Activity Is Associated With the Progression of Kidney Disease in Finnish Patients With Type 1 Diabetes

(2009) M. Nymark et al.   DIABETES CARE

Genetic Variation and Population Substructure in Outbred CD-1 Mice: Implications for Genome-Wide Association Studies

(2009) Kimberly A. Aldinger et al.   PLoS One

Systemic Administration of Multipotent Mesenchymal Stromal Cells Reverts Hyperglycemia and Prevents Nephropathy in Type 1 Diabetic Mice

(2008) Fernando E. Ezquer et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury

(2007) P.L. Zhang et al.   KIDNEY INTERNATIONAL