期刊
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
卷 100, 期 15, 页码 6601-6617出版社
SPRINGER
DOI: 10.1007/s00253-016-7671-9
关键词
Fungi; Proteins; Antibacterial; Antifungal; Antiviral; Anticancer
资金
- Food and Health Bureau, Hong Kong Special Administration Region Government [12131221, 12110282]
- National Natural Science Foundation of China [81201270, 81471927]
- Medicine Panel, Research Committee, of the Chinese University of Hong Kong [4054049, 4054135]
Fungi comprise organisms like molds, yeasts and mushrooms. They have been used as food or medicine for a long time. A large number of fungal proteins or peptides with diverse biological activities are considered as antibacterial, antifungal, antiviral and anticancer agents. They encompass proteases, ribosome inactivating proteins, defensins, hemolysins, lectins, laccases, ribonucleases, immunomodulatory proteins, and polysaccharopeptides. The target of the present review is to update the status of the various bioactivities of these fungal proteins and peptides and discuss their therapeutic potential.
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