MIR145-3p promotes autophagy and enhances bortezomib sensitivity in multiple myeloma by targeting HDAC4

Combined inhibition of EGFR and c-ABL suppresses the growth of fulvestrant-resistant breast cancer cells through miR-375-autophagy axis

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Resistance to proteasome inhibitors and other targeted therapies in myeloma

(2018) Craig T. Wallington-Beddoe et al.   BRITISH JOURNAL OF HAEMATOLOGY

MicroRNA-30a suppresses autophagy-mediated anoikis resistance and metastasis in hepatocellular carcinoma

(2018) Xiu-Tao Fu et al.   CANCER LETTERS

miR-142-3p regulates autophagy by targeting ATG16L1 in thymic-derived regulatory T cell (tTreg)

(2018) Yunjie Lu et al.   Cell Death & Disease

Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis

(2017) Jahangir Abdi et al.   Journal of Hematology & Oncology

Dual role of autophagy in hallmarks of cancer

(2017) Shikha Satendra Singh et al.   ONCOGENE

Overexpression of miR-140 Inhibits Proliferation of Osteosarcoma Cells via Suppression of Histone Deacetylase 4

(2017) Qianren Xiao et al.   ONCOLOGY RESEARCH

Inhibition of EZH2 triggers the tumor suppressive miR-29b network in multiple myeloma

(2017) Maria Angelica Stamato et al.   Oncotarget

miR-181a suppresses autophagy and sensitizes gastric cancer cells to cisplatin

(2016) Jing Zhao et al.   GENE

Autophagy in Plasma Cell Ontogeny and Malignancy

(2016) Enrico Milan et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Novel agents in the treatment of multiple myeloma: a review about the future

(2016) Leonard Naymagon et al.   Journal of Hematology & Oncology

Histone deacetylase inhibitors interrupt HSP90•RASGRP1 and HSP90•CRAF interactions to upregulate BIM and circumvent drug resistance in lymphoma cells

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Therapeutic Targeting of miR-29b/HDAC4 Epigenetic Loop in Multiple Myeloma

(2016) Nicola Amodio et al.   MOLECULAR CANCER THERAPEUTICS

A network-biology perspective of microRNA function and dysfunction in cancer

(2016) Cameron P. Bracken et al.   NATURE REVIEWS GENETICS

Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4

(2015) Aamir Ahmad et al.   BMC CANCER

Multiple myeloma

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Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma

(2015) S Kikuchi et al.   LEUKEMIA

TGF-β1 Reduces miR-29a Expression to Promote Tumorigenicity and Metastasis of Cholangiocarcinoma by Targeting HDAC4

(2015) Huiling Wang et al.   PLoS One

Iron chelators induce autophagic cell death in multiple myeloma cells

(2014) Vinod Pullarkat et al.   LEUKEMIA RESEARCH

Synthetic miR-145 mimic inhibits multiple myeloma cell growth in vitro and in vivo

(2014) QI ZHANG et al.   ONCOLOGY REPORTS

Histone Deacetylase HDAC4 Promotes Gastric Cancer SGC-7901 Cells Progression via p21 Repression

(2014) Zhen-Hua Kang et al.   PLoS One

Clioquinol induces pro-death autophagy in leukemia and myeloma cells by disrupting the mTOR signaling pathway

(2014) Biyin Cao et al.   Scientific Reports

Autophagy and Its Effects: Making Sense of Double-Edged Swords

(2014) Andrew Thorburn   PLOS BIOLOGY

The role of autophagy in plasma cell ontogenesis

(2013) Niccolò Pengo et al.   Autophagy

Autophagy

(2013) Amber N. Hale et al.   Autophagy

Suberoylanilide hydroxamic acid (SAHA) causes tumor growth slowdown and triggers autophagy in glioblastoma stem cells

(2013) Ming-Tsang Chiao et al.   Autophagy

Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma

(2013) Laurence Lamy et al.   CANCER CELL

MIR106B and MIR93 Prevent Removal of Bacteria From Epithelial Cells by Disrupting ATG16L1-Mediated Autophagy

(2013) Changming Lu et al.   GASTROENTEROLOGY

MicroRNA-101 inhibits human hepatocellular carcinoma progression through EZH2 downregulation and increased cytostatic drug sensitivity

(2013) Leibo Xu et al.   JOURNAL OF HEPATOLOGY

MicroRNA theragnostics for the clinical management of multiple myeloma

(2013) N Ahmad et al.   LEUKEMIA

Plasma cells require autophagy for sustainable immunoglobulin production

(2013) Niccolò Pengo et al.   NATURE IMMUNOLOGY

miR-155 targets histone deacetylase 4 (HDAC4) and impairs transcriptional activity of B-cell lymphoma 6 (BCL6) in the E -miR-155 transgenic mouse model

(2012) S. K. Sandhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of autophagy in histone deacetylase inhibitor-induced apoptotic and nonapoptotic cell death

(2012) N. Gammoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

(2010) Yuan-Ling Liu et al.   Autophagy

MicroRNAs and Cancer: Short RNAs Go a Long Way

(2009) Andrea Ventura et al.   CELL

HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21

(2008) Andrew J. Wilson et al.   MOLECULAR BIOLOGY OF THE CELL