c-Cbl: An Important Regulator and a Target in Angiogenesis and Tumorigenesis

c-Cbl Expression Correlates with Human Colorectal Cancer Survival and Its Wnt/β-Catenin Suppressor Function Is Regulated by Tyr371 Phosphorylation

(2018) Sowmiya Kumaradevan et al.   AMERICAN JOURNAL OF PATHOLOGY

VEGF - A Stimulus for Neuronal Development and Regeneration in the CNS and PNS

(2018) Verena Theis et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities

(2018) Yazhuo Zhang et al.   Molecular Cancer

The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src

(2018) Gun-Woo Lee et al.   ONCOGENE

Ubiquitylation at the crossroads of development and disease

(2017) Michael Rape   NATURE REVIEWS MOLECULAR CELL BIOLOGY

WNT Signaling in Cardiac and Vascular Disease

(2017) Sébastien Foulquier et al.   PHARMACOLOGICAL REVIEWS

Dysregulation of angiogenesis-specific signalling in adult testis results in xenograft degeneration

(2017) Lalitha Devi et al.   Scientific Reports

Angiogenesis Dysregulation in the Pathogenesis of Systemic Sclerosis

(2017) Francesco Paolo Cantatore et al.   Biomed Research International

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation

(2016) Lori Buetow et al.   BMC BIOLOGY

The Wnt signaling pathway in cancer

(2016) Yann Duchartre et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Wnt signaling in cancer

(2016) T Zhan et al.   ONCOGENE

Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation

(2016) Chandrani Mukhopadhyay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance to anti-VEGF therapy in neovascular age-related macular degeneration: a comprehensive review

(2016) Xiaodong Sun et al.   Drug Design Development and Therapy

c-Cbl mediates the degradation of tumorigenic nuclear β-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors

(2016) Moshe Shashar et al.   Oncotarget

VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis

(2016) Chandran S. Abhinand et al.   Journal of Cell Communication and Signaling

The c-Cbl Ubiquitin Ligase Regulates Nuclear β-Catenin and Angiogenesis by Its Tyrosine Phosphorylation Mediated through the Wnt Signaling Pathway

(2015) Sowmya Shivanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma

(2015) Hans Prenen et al.   Oncotarget

Novel strategies to target the ubiquitin proteasome system in multiple myeloma

(2015) Susanne Lub et al.   Oncotarget

Modulation of Immune Cell Functions by the E3 Ligase Cbl-b

(2015) Christina Lutz-Nicoladoni et al.   Frontiers in Oncology

Targeting the Ubiquitin-Proteasome System in Heart Disease: The Basis for New Therapeutic Strategies

(2014) Oliver Drews et al.   ANTIOXIDANTS & REDOX SIGNALING

c-Cbl Inhibition Improves Cardiac Function and Survival in Response to Myocardial Ischemia

(2014) Khadija Rafiq et al.   CIRCULATION

Roles of VEGF-A signalling in development, regeneration, and tumours

(2014) K. Matsumoto et al.   JOURNAL OF BIOCHEMISTRY

Emerging therapies targeting the ubiquitin proteasome system in cancer

(2014) Nathaniel M. Weathington et al.   JOURNAL OF CLINICAL INVESTIGATION

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

(2014) Sam Behjati et al.   NATURE GENETICS

Emerging roles of post-translational modifications in signal transduction and angiogenesis

(2014) Nader Rahimi et al.   PROTEOMICS

Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers

(2013) Kai Hung Tiong et al.   APOPTOSIS

Genetic Reduction of Vascular Endothelial Growth Factor Receptor 2 Rescues Aberrant Angiogenesis Caused by Epsin Deficiency

(2013) Kandice L. Tessneer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Wnt signaling in the vasculature

(2013) Marco Reis et al.   EXPERIMENTAL CELL RESEARCH

c-Cbl, a Ubiquitin E3 Ligase That Targets Active β-Catenin

(2013) Vipul Chitalia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VEGFA and tumour angiogenesis

(2013) L. Claesson-Welsh et al.   JOURNAL OF INTERNAL MEDICINE

Multiple functions of the noncanonical Wnt pathway

(2013) Eva Gómez-Orte et al.   TRENDS IN GENETICS

Obstructive Coronary Atherosclerosis and Ischemic Heart Disease: An Elusive Link!

(2012) Mario Marzilli et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Ubiquitin-Proteasome System Meets Angiogenesis

(2012) N. Rahimi   MOLECULAR CANCER THERAPEUTICS

Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl

(2012) Hao Dou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanisms of Age-Related Macular Degeneration

(2012) Jayakrishna Ambati et al.   NEURON

Alternative Wnt Pathways and Receptors

(2012) R. van Amerongen   Cold Spring Harbor Perspectives in Biology

Pericyte-endothelial cell interaction

(2012) Sharmila Chatterjee et al.   Cell Adhesion & Migration

c-Cbl inhibits angiogenesis and tumor growth by suppressing activation of PLCγ1

(2011) R D Meyer et al.   ONCOGENE

Noncanonical Wnt signaling in vertebrate development, stem cells, and diseases

(2010) Ryohichi Sugimura et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Roles of Fibroblast Growth Factor Receptors in Carcinogenesis

(2010) E. M. Haugsten et al.   MOLECULAR CANCER RESEARCH

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Angiopoietin-1-induced ubiquitylation of Tie2 by c-Cbl is required for internalization and degradation

(2009) Christina Wehrle et al.   BIOCHEMICAL JOURNAL

A role for protein ubiquitination in VEGFR-2 signalling and angiogenesis

(2009) Nader Rahimi   BIOCHEMICAL SOCIETY TRANSACTIONS

Wnt/Planar cell polarity signaling: A new paradigm for cancer therapy

(2009) Y. Wang   MOLECULAR CANCER THERAPEUTICS

The Role of Src in Solid Tumors

(2009) D. L. Wheeler et al.   ONCOLOGIST