APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice
出版年份 2019 全文链接
标题
APOE genotype and sex affect microglial interactions with plaques in Alzheimer’s disease mice
作者
关键词
-
出版物
Acta Neuropathologica Communications
Volume 7, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-05-21
DOI
10.1186/s40478-019-0729-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Role of APOE4 in Disrupting the Homeostatic Functions of Astrocytes and Microglia in Aging and Alzheimer’s Disease
- (2019) Celia G. Fernandez et al. Frontiers in Aging Neuroscience
- Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology
- (2019) Hassan El Hajj et al. Journal of Neuroinflammation
- Microglia-Mediated Neuroprotection, TREM2 , and Alzheimer’s Disease: Evidence From Optical Imaging
- (2018) Carlo Condello et al. BIOLOGICAL PSYCHIATRY
- Plaque-dependent morphological and electrophysiological heterogeneity of microglia in an Alzheimer's disease mouse model
- (2018) Monika Plescher et al. GLIA
- ApoE facilitates the microglial response to amyloid plaque pathology
- (2018) Jason D. Ulrich et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism
- (2018) Wilbur M. Song et al. JOURNAL OF EXPERIMENTAL MEDICINE
- APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
- (2018) Yuan-Ta Lin et al. NEURON
- Brain Response to Injuries: When Microglia Go Sexist
- (2018) Reza Rahimian et al. NEUROSCIENCE
- A transcriptomic atlas of aged human microglia
- (2018) Marta Olah et al. Nature Communications
- Sex-Specific Features of Microglia from Adult Mice
- (2018) Alessandro Villa et al. Cell Reports
- The Role of APOE and TREM2 in Alzheimer′s Disease—Current Understanding and Perspectives
- (2018) Cody Wolfe et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
- (2018) Samira Parhizkar et al. NATURE NEUROSCIENCE
- A Tale of Two Genes: Microglial Apoe and Trem2
- (2017) Anna A. Pimenova et al. IMMUNITY
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer’s disease
- (2017) Leon M. Tai et al. JOURNAL OF LIPID RESEARCH
- The Alzheimer’s disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway
- (2017) Charlotte Jendresen et al. Journal of Neuroinflammation
- Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer’s disease
- (2017) Ruohe Zhao et al. Molecular Neurodegeneration
- TREM2 in Neurodegenerative Diseases
- (2017) Taylor R. Jay et al. Molecular Neurodegeneration
- Interactions between inflammation, sex steroids, and Alzheimer’s disease risk factors
- (2016) Mariana F. Uchoa et al. FRONTIERS IN NEUROENDOCRINOLOGY
- TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
- (2016) Yaming Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sex and the development of Alzheimer's disease
- (2016) Christian J. Pike JOURNAL OF NEUROSCIENCE RESEARCH
- Sex differences in neurodevelopmental and neurodegenerative disorders: Focus on microglial function and neuroinflammation during development
- (2016) Richa Hanamsagar et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice
- (2016) Mafalda Cacciottolo et al. NEUROBIOLOGY OF AGING
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- Emerging Concepts in Alzheimer's Disease
- (2015) Harry V. Vinters Annual Review of Pathology-Mechanisms of Disease
- Alzheimer’s Disease Risk Genes and Mechanisms of Disease Pathogenesis
- (2015) Celeste M. Karch et al. BIOLOGICAL PSYCHIATRY
- TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
- (2015) Yaming Wang et al. CELL
- Different mechanisms of apolipoprotein E isoform–dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia
- (2015) Xianwu Li et al. FASEB JOURNAL
- Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)
- (2015) Yuka Atagi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E
- (2015) Charles C. Bailey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TREM2 sustains microglial expansion during aging and response to demyelination
- (2015) Pietro Luigi Poliani et al. JOURNAL OF CLINICAL INVESTIGATION
- APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective
- (2015) Leon M. Tai et al. JOURNAL OF NEUROCHEMISTRY
- Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling
- (2015) T.-L. Stephen et al. JOURNAL OF NEUROSCIENCE
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques
- (2015) Carlo Condello et al. Nature Communications
- Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
- (2015) Inge R Holtman et al. Acta Neuropathologica Communications
- Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice
- (2014) Oleg Butovsky et al. ANNALS OF NEUROLOGY
- Sex modifies theAPOE-related risk of developing Alzheimer disease
- (2014) Andre Altmann et al. ANNALS OF NEUROLOGY
- Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition
- (2014) Gustavo A Rodriguez et al. Journal of Neuroinflammation
- Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2
- (2014) Jason D Ulrich et al. Molecular Neurodegeneration
- Genetics of Alzheimer’s Disease
- (2014) Rita Guerreiro et al. Neurotherapeutics
- APOE3, but Not APOE4, Bone Marrow Transplantation Mitigates Behavioral and Pathological Changes in a Mouse Model of Alzheimer Disease
- (2013) Yue Yang et al. AMERICAN JOURNAL OF PATHOLOGY
- Microglia Are Essential to Masculinization of Brain and Behavior
- (2013) K. M. Lenz et al. JOURNAL OF NEUROSCIENCE
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- The microglial sensome revealed by direct RNA sequencing
- (2013) Suzanne E Hickman et al. NATURE NEUROSCIENCE
- APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease
- (2012) Katherine L. Youmans et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
- (2012) Emmanuel L Gautier et al. NATURE IMMUNOLOGY
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- An Automated Method to Quantify Microglia Morphology and Application to Monitor Activation State Longitudinally In Vivo
- (2012) Cleopatra Kozlowski et al. PLoS One
- The role of microglia in amyloid clearance from the AD brain
- (2010) C. Y. Daniel Lee et al. JOURNAL OF NEURAL TRANSMISSION
- TREM2- and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1
- (2010) Q. Peng et al. Science Signaling
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
- Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance
- (2008) T. Bolmont et al. JOURNAL OF NEUROSCIENCE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now