标题
Material design for lymph node drug delivery
作者
关键词
-
出版物
Nature Reviews Materials
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-05-02
DOI
10.1038/s41578-019-0110-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Winner of the society for biomaterials young investigator award for the annual meeting of the society for biomaterials, April 11-14, 2018, Atlanta, GA: S-nitrosated poly(propylene sulfide) nanoparticles for enhanced nitric oxide delivery to lymphatic tiss
- (2018) Alex Schudel et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Sustained micellar delivery via inducible transitions in nanostructure morphology
- (2018) Nicholas B. Karabin et al. Nature Communications
- Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival
- (2018) Baharak Bahmani et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of gold nanoparticle-based vaccine size on lymph node delivery and cytotoxic T-lymphocyte responses
- (2017) Sukmo Kang et al. JOURNAL OF CONTROLLED RELEASE
- Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
- (2017) Peter Popp Wibroe et al. Nature Nanotechnology
- The molecular cues regulating immune cell trafficking
- (2017) Akira TAKEDA et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
- (2017) Daniela Schmid et al. Nature Communications
- Biophysical Attributes of CpG Presentation Control TLR9 Signaling to Differentially Polarize Systemic Immune Responses
- (2017) Jardin A. Leleux et al. Cell Reports
- High Endothelial Venules and Other Blood Vessels: Critical Regulators of Lymphoid Organ Development and Function
- (2017) Ann Ager Frontiers in Immunology
- A novel treatment for metastatic lymph nodes using lymphatic delivery and photothermal therapy
- (2017) Adewale O. Oladipo et al. Scientific Reports
- Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability
- (2016) Luojuan Hu et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Implications of Lymphatic Transport to Lymph Nodes in Immunity and Immunotherapy
- (2016) Susan N. Thomas et al. Annual Review of Biomedical Engineering
- Melanoma growth effects on molecular clearance from tumors and biodistribution into systemic tissues versus draining lymph nodes
- (2016) Nathan Andrew Rohner et al. JOURNAL OF CONTROLLED RELEASE
- Constitutive Triglyceride Turnover into the Mesenteric Lymph Is Unable to Support Efficient Lymphatic Transport of a Biomimetic Triglyceride Prodrug
- (2016) Sifei Han et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
- (2016) Matthias A. Oberli et al. NANO LETTERS
- Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells
- (2016) Catherine A. Fromen et al. Nanomedicine-Nanotechnology Biology and Medicine
- Pulmonary delivery of cationic gold nanoparticles boost antigen-specific CD4 + T Cell Proliferation
- (2016) Emilie Seydoux et al. Nanomedicine-Nanotechnology Biology and Medicine
- Designer vaccine nanodiscs for personalized cancer immunotherapy
- (2016) Rui Kuai et al. NATURE MATERIALS
- pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation
- (2016) Lutz Nuhn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions
- (2016) F. Pucci et al. SCIENCE
- Targeted Delivery of Immunomodulators to Lymph Nodes
- (2016) Jamil Azzi et al. Cell Reports
- Reprogramming the Local Lymph Node Microenvironment Promotes Tolerance that Is Systemic and Antigen Specific
- (2016) Lisa H. Tostanoski et al. Cell Reports
- Flexible Macromolecule versus Rigid Particle Retention in the Injected Skin and Accumulation in Draining Lymph Nodes Are Differentially Influenced by Hydrodynamic Size
- (2016) Nathan Andrew Rohner et al. ACS Biomaterials-Science & Engineering
- Flexible Macromolecule versus Rigid Particle Retention in the Injected Skin and Accumulation in Draining Lymph Nodes Are Differentially Influenced by Hydrodynamic Size
- (2016) Nathan Andrew Rohner et al. ACS Biomaterials Science & Engineering
- Lymphatic transport of exosomes as a rapid route of information dissemination to the lymph node
- (2016) Swetha Srinivasan et al. Scientific Reports
- Systemic Targeting of Lymph Node Metastasis through the Blood Vascular System by Using Size-Controlled Nanocarriers
- (2015) Horacio Cabral et al. ACS Nano
- Pulmonary Delivery of siRNA via Polymeric Vectors as Therapies of Asthma
- (2015) Yuran Xie et al. ARCHIV DER PHARMAZIE
- Paracrine co-delivery of TGF-β and IL-2 using CD4-targeted nanoparticles for induction and maintenance of regulatory T cells
- (2015) Michael D. McHugh et al. BIOMATERIALS
- Lymph node biophysical remodeling is associated with melanoma lymphatic drainage
- (2015) Nathan Andrew Rohner et al. FASEB JOURNAL
- Shape and size-dependent immune response to antigen-carrying nanoparticles
- (2015) Sunny Kumar et al. JOURNAL OF CONTROLLED RELEASE
- The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes
- (2015) Pia Rantakari et al. NATURE IMMUNOLOGY
- The development and function of lung-resident macrophages and dendritic cells
- (2015) Manfred Kopf et al. NATURE IMMUNOLOGY
- From sewer to saviour — targeting the lymphatic system to promote drug exposure and activity
- (2015) Natalie L. Trevaskis et al. NATURE REVIEWS DRUG DISCOVERY
- A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep
- (2015) Gemma M. Ryan et al. PHARMACEUTICAL RESEARCH
- CD169+macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells
- (2015) Caroline A. Bernhard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Active targeting of chemotherapy to disseminated tumors using nanoparticle-carrying T cells
- (2015) Bonnie Huang et al. Science Translational Medicine
- The lymph node microenvironment and its role in the progression of metastatic cancer
- (2015) Ethel R. Pereira et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies
- (2015) Shujing Wang et al. Protein & Cell
- Overcoming transport barriers for interstitial-, lymphatic-, and lymph node-targeted drug delivery
- (2015) Susan N Thomas et al. Current Opinion in Chemical Engineering
- Reprogramming the tumor microenvironment: tumor-induced immunosuppressive factors paralyze T cells
- (2015) Annie A Wu et al. OncoImmunology
- Tumor Metastasis Inhibition by Imaging-Guided Photothermal Therapy with Single-Walled Carbon Nanotubes
- (2014) Chao Liang et al. ADVANCED MATERIALS
- In Situ Modulation of Dendritic Cells by Injectable Thermosensitive Hydrogels for Cancer Vaccines in Mice
- (2014) Yarong Liu et al. BIOMACROMOLECULES
- Targeting nanoparticles to CD40, DEC-205 or CD11c molecules on dendritic cells for efficient CD8+ T cell response: A comparative study
- (2014) Luis J. Cruz et al. JOURNAL OF CONTROLLED RELEASE
- Neutral polymer micelle carriers with pH-responsive, endosome-releasing activity modulate antigen trafficking to enhance CD8+ T cell responses
- (2014) Salka Keller et al. JOURNAL OF CONTROLLED RELEASE
- Structure-based programming of lymph-node targeting in molecular vaccines
- (2014) Haipeng Liu et al. NATURE
- Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization
- (2014) Catherine A. Fromen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lymphatic-targeted cationic liposomes: A robust vaccine adjuvant for promoting long-term immunological memory
- (2014) Ce Wang et al. VACCINE
- Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes
- (2014) L. Jeanbart et al. Cancer Immunology Research
- Differential Roles of Lung Dendritic Cell Subsets Against Respiratory Virus Infection
- (2014) Tae Hoon Kim et al. Immune Network
- Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses
- (2013) Marija Zaric et al. ACS Nano
- Size-Dependent Uptake of Particles by Pulmonary Antigen-Presenting Cell Populations and Trafficking to Regional Lymph Nodes
- (2013) Fabian Blank et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Intraoperative Clinical Assessment and Pressure Measurements of Sentinel Lymph Nodes in Breast Cancer
- (2013) S. David Nathanson et al. ANNALS OF SURGICAL ONCOLOGY
- Particle shape dependence of CD8+ T cell activation by artificial antigen presenting cells
- (2013) Joel C. Sunshine et al. BIOMATERIALS
- Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response
- (2013) Susan N. Thomas et al. BIOMATERIALS
- CD169 mediates the capture of exosomes in spleen and lymph node
- (2013) S. C. Saunderson et al. BLOOD
- Lymphatic system: a prospective area for advanced targeting of particulate drug carriers
- (2013) Indu Singh et al. Expert Opinion on Drug Delivery
- Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Antigen Binding and Activation
- (2013) Balthasar A. Heesters et al. IMMUNITY
- PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin
- (2013) Gemma M. Ryan et al. JOURNAL OF CONTROLLED RELEASE
- In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes
- (2013) Yiran Zheng et al. JOURNAL OF CONTROLLED RELEASE
- Differential Uptake of Nanoparticles and Microparticles by Pulmonary APC Subsets Induces Discrete Immunological Imprints
- (2013) C. L. Hardy et al. JOURNAL OF IMMUNOLOGY
- Topical Vaccination with Functionalized Particles Targeting Dendritic Cells
- (2013) Renato B. Baleeiro et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Langerin + Dermal DC, but Not Langerhans Cells, Are Required for Effective CD8-Mediated Immune Responses after Skin Scarification with Vaccinia Virus
- (2013) Julien Seneschal et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections
- (2013) M Guilliams et al. Mucosal Immunology
- Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice
- (2013) Iraklis C. Kourtis et al. PLoS One
- Mammalian cells preferentially internalize hydrogel nanodiscs over nanorods and use shape-specific uptake mechanisms
- (2013) R. Agarwal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nanoparticle conjugation of CpG enhances adjuvancy for cellular immunity and memory recall at low dose
- (2013) A. de Titta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Dendritic Cell Response to Classic, Emerging, and Homeostatic Danger Signals. Implications for Autoimmunity
- (2013) Paul M. Gallo et al. Frontiers in Immunology
- A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread
- (2012) Wolfgang Kastenmüller et al. CELL
- Lymph Node Macrophages
- (2012) Elizabeth E. Gray et al. Journal of Innate Immunity
- Differentiation of Reactive and Tumor Metastatic Lymph Nodes with Diffusion-weighted and SPIO-Enhanced MRI
- (2012) Fan Zhang et al. MOLECULAR IMAGING AND BIOLOGY
- Advances in lymphatic imaging and drug delivery
- (2011) Satish K. Nune et al. ADVANCED DRUG DELIVERY REVIEWS
- Functional Contributions of N- and O-Glycans to L-Selectin Ligands in Murine and Human Lymphoid Organs
- (2011) Hanayo Arata-Kawai et al. AMERICAN JOURNAL OF PATHOLOGY
- Lymphatic Vessels and High Endothelial Venules are Increased in the Sentinel Lymph Nodes of Patients with Oral Squamous Cell Carcinoma Before the Arrival of Tumor Cells
- (2011) Man Ki Chung et al. ANNALS OF SURGICAL ONCOLOGY
- Sentinel Lymph Node Pressure in Breast Cancer
- (2011) S. David Nathanson et al. ANNALS OF SURGICAL ONCOLOGY
- Intra-Lymph Node Prime-Boost Vaccination against Melan A and Tyrosinase for the Treatment of Metastatic Melanoma: Results of a Phase 1 Clinical Trial
- (2011) A. Ribas et al. CLINICAL CANCER RESEARCH
- In situ engineering of the lymph node microenvironment via intranodal injection of adjuvant-releasing polymer particles
- (2011) C. M. Jewell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Lymph Node Revisited: Development, Morphology, Functioning, and Role in Triggering Primary Immune Responses
- (2010) Guy Sainte-Marie Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Intracellular Delivery of a Protein Antigen with an Endosomal-Releasing Polymer Enhances CD8 T-Cell Production and Prophylactic Vaccine Efficacy
- (2010) Suzanne Foster et al. BIOCONJUGATE CHEMISTRY
- Overview of the immune response
- (2010) David D. Chaplin JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Novel Anti-carbohydrate Antibodies Reveal the Cooperative Function of SulfatedN- andO-Glycans in Lymphocyte Homing
- (2010) Jotaro Hirakawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems
- (2010) Deepa Mohanan et al. JOURNAL OF CONTROLLED RELEASE
- A Protease-Dependent Mechanism for Initiating T-Dependent B Cell Responses to Large Particulate Antigens
- (2010) D. M. Catron et al. JOURNAL OF IMMUNOLOGY
- Complement-Dependent Transport of Antigen into B Cell Follicles
- (2010) S. F. Gonzalez et al. JOURNAL OF IMMUNOLOGY
- Rapid translocation of nanoparticles from the lung airspaces to the body
- (2010) Hak Soo Choi et al. NATURE BIOTECHNOLOGY
- Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
- (2010) Matthias T Stephan et al. NATURE MEDICINE
- In vivo function of Langerhans cells and dermal dendritic cells
- (2010) Daniel H. Kaplan TRENDS IN IMMUNOLOGY
- In-situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA–DNA carrying microparticles to dendritic cells
- (2009) Ankur Singh et al. BIOMATERIALS
- B cell acquisition of antigen in vivo
- (2009) Santiago F Gonzalez et al. CURRENT OPINION IN IMMUNOLOGY
- Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles
- (2009) Ramon Roozendaal et al. IMMUNITY
- PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats
- (2009) Lisa M. Kaminskas et al. JOURNAL OF CONTROLLED RELEASE
- Biodegradable PLGA based nanoparticles for sustained regional lymphatic drug delivery
- (2009) Deepa A. Rao et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation
- (2009) Tri Giang Phan et al. NATURE IMMUNOLOGY
- Infection-mimicking materials to program dendritic cells in situ
- (2009) Omar A. Ali et al. NATURE MATERIALS
- Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions
- (2009) K. Nagao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhancing DNA vaccination by sequential injection of lymph nodes with plasmid vectors and peptides
- (2009) Kent A. Smith et al. VACCINE
- Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
- (2008) Olivier Joffre et al. IMMUNOLOGICAL REVIEWS
- Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells By Hair Follicles and their Transport in Mice
- (2008) Brice Mahe et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The lymph node in HIV pathogenesis
- (2008) Michael M. Lederman et al. SEMINARS IN IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation