The Bile Acid TUDCA Improves Beta-Cell Mass and Reduces Insulin Degradation in Mice With Early-Stage of Type-1 Diabetes

Withaferin-A attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes

(2018) Sravani Tekula et al.   BIOMEDICINE & PHARMACOTHERAPY

Nanoceria suppresses multiple low doses of streptozotocin-induced Type 1 diabetes by inhibition of Nrf2/NF-κB pathway and reduction of apoptosis

(2018) Amit Khurana et al.   Nanomedicine

Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α

(2017) Gail J. Ocaña et al.   IMMUNOLOGY

Bile acid TUDCA improves insulin clearance by increasing the expression of insulin-degrading enzyme in the liver of obese mice

(2017) Jean Franciesco Vettorazzi et al.   Scientific Reports

Type 1 diabetes mellitus

(2017) Anastasia Katsarou et al.   Nature Reviews Disease Primers

A systematic review of interventions to improve outcomes for young adults with Type 1 diabetes

(2016) M. C. O'Hara et al.   DIABETIC MEDICINE

Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice

(2016) Aine M. McKillop et al.   DIABETOLOGIA

Acute exercise restores insulin clearance in diet-induced obese mice

(2016) Mirian A Kurauti et al.   JOURNAL OF ENDOCRINOLOGY

The bile acid TUDCA increases glucose-induced insulin secretion via the cAMP/PKA pathway in pancreatic beta cells

(2016) Jean Franciesco Vettorazzi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Vagotomy ameliorates islet morphofunction and body metabolic homeostasis in MSG-obese rats

(2015) C. Lubaczeuski et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Pharmacologic Therapy of Diabetes and Overall Cancer Risk and Mortality: A Meta-Analysis of 265 Studies

(2015) Lang Wu et al.   Scientific Reports

Type 1 Diabetes Through the Life Span: A Position Statement of the American Diabetes Association

(2014) Jane L. Chiang et al.   DIABETES CARE

Glycemic Control and Excess Mortality in Type 1 Diabetes

(2014) Marcus Lind et al.   NEW ENGLAND JOURNAL OF MEDICINE

Barriers and facilitators associated with attendance at hospital diabetes clinics among young adults (15-30 years) with type 1 diabetes mellitus: a systematic review

(2014) Lisa Hynes et al.   PEDIATRIC DIABETES

Chaperones Ameliorate Beta Cell Dysfunction Associated with Human Islet Amyloid Polypeptide Overexpression

(2014) Lisa Cadavez et al.   PLoS One

From immunobiology to β-cell biology: The changing perspective on type 1 diabetes

(2014) Aarthi Maganti et al.   Islets

Type 1 diabetes

(2013) Mark A Atkinson et al.   LANCET

Restoration of the Unfolded Protein Response in Pancreatic   Cells Protects Mice Against Type 1 Diabetes

(2013) F. Engin et al.   Science Translational Medicine

Predictors of Deteriorations in Diabetes Management and Control in Adolescents With Type 1 Diabetes

(2012) Marisa E. Hilliard et al.   JOURNAL OF ADOLESCENT HEALTH

The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure

(2011) Wagner S. da-Silva et al.   FEBS LETTERS

Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes

(2011) Elaine Studer et al.   HEPATOLOGY

Tauroursodeoxycholate (TUDCA), chemical chaperone, enhances function of islets by reducing ER stress

(2010) Yeon Yi Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women

(2010) Marleen Kars et al.   DIABETES

Effectiveness of Sensor-Augmented Insulin-Pump Therapy in Type 1 Diabetes

(2010) Richard M. Bergenstal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Weight-dependent differential contribution of insulin secretion and clearance to hyperinsulinemia of obesity

(2008) Johannes Erdmann et al.   REGULATORY PEPTIDES