Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice
出版年份 2016 全文链接
标题
Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice
作者
关键词
Beta cell regeneration, Diabetes, Fatty acid agonists, Glucose homeostasis, G-protein-coupled receptors, Insulin secretion, Multiple low-dose streptozotocin
出版物
DIABETOLOGIA
Volume 59, Issue 12, Pages 2674-2685
出版商
Springer Nature
发表日期
2016-09-27
DOI
10.1007/s00125-016-4108-z
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- G protein-coupled receptors: signalling and regulation by lipid agonists for improved glucose homoeostasis
- (2016) Brian M. Moran et al. ACTA DIABETOLOGICA
- GPR119 Agonist AS1269574 Activates TRPA1 Cation Channels to Stimulate GLP-1 Secretion
- (2016) Oleg G. Chepurny et al. MOLECULAR ENDOCRINOLOGY
- GPR39 receptors and actions of trace metals on pancreatic beta cell function and glucose homoeostasis
- (2015) Brian. M. Moran et al. ACTA DIABETOLOGICA
- Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity
- (2015) A Meadows et al. INTERNATIONAL JOURNAL OF OBESITY
- GPR55: From orphan to metabolic regulator?
- (2015) Bo Liu et al. PHARMACOLOGY & THERAPEUTICS
- Physiology of Proglucagon Peptides: Role of Glucagon and GLP-1 in Health and Disease
- (2015) Darleen A. Sandoval et al. PHYSIOLOGICAL REVIEWS
- Activation of GPR119 by fatty acid agonists augments insulin release from clonal β-cells and isolated pancreatic islets and improves glucose tolerance in mice
- (2013) Brian M. Moran et al. BIOLOGICAL CHEMISTRY
- Glucose-dependent insulinotropic polypeptide (GIP) receptor deletion leads to reduced bone strength and quality
- (2013) Aleksandra Mieczkowska et al. BONE
- Evaluation of the insulin releasing and antihyperglycaemic activities of GPR55 lipid agonists using clonal beta-cells, isolated pancreatic islets and mice
- (2013) A M McKillop et al. BRITISH JOURNAL OF PHARMACOLOGY
- Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics
- (2013) Tomo Yonezawa et al. CURRENT MEDICINAL CHEMISTRY
- Optimal bone mechanical and material properties require a functional glucagon-like peptide-1 receptor
- (2013) Guillaume Mabilleau et al. JOURNAL OF ENDOCRINOLOGY
- Stimulation of Proglucagon Gene Expression by Human GPR119 in Enteroendocrine L-cell Line GLUTag
- (2013) Oleg G. Chepurny et al. MOLECULAR ENDOCRINOLOGY
- Stimulating β-Cell Regeneration by Combining a GPR119 Agonist with a DPP-IV Inhibitor
- (2013) Ansarullah et al. PLoS One
- High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound with Anti-Diabetic Efficacy in db/db Mice
- (2013) Meng Zhang et al. PLoS One
- The L- -Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity
- (2011) J. M. Moreno-Navarrete et al. DIABETES
- Incretin Effects on -Cell Function, Replication, and Mass: The human perspective
- (2011) A. J. Garber DIABETES CARE
- A role for the putative cannabinoid receptor GPR55 in the islets of Langerhans
- (2011) Silvana Y Romero-Zerbo et al. JOURNAL OF ENDOCRINOLOGY
- Ranolazine Increases -Cell Survival and Improves Glucose Homeostasis in Low-Dose Streptozotocin-Induced Diabetes in Mice
- (2011) Y. Ning et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents
- (2011) X.-H. Lin et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Stimulating beta cell replication and improving islet graft function by GPR119 agonists
- (2011) Jie Gao et al. TRANSPLANT INTERNATIONAL
- AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes
- (2010) Shigeru Yoshida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated insulin secretion
- (2010) Shigeru Yoshida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Animal research: Reporting in vivo experiments: The ARRIVE guidelines
- (2010) Carol Kilkenny et al. BRITISH JOURNAL OF PHARMACOLOGY
- GPR119 Regulates Murine Glucose Homeostasis Through Incretin Receptor-Dependent and Independent Mechanisms
- (2010) Grace Flock et al. ENDOCRINOLOGY
- Review: Hydroxyoctadecadienoic acids: novel regulators of macrophage differentiation and atherogenesis
- (2010) Venkat Vangaveti et al. Therapeutic Advances in Endocrinology and Metabolism
- GPR119 Is Essential for Oleoylethanolamide-Induced Glucagon-Like Peptide-1 Secretion From the Intestinal Enteroendocrine L-Cell
- (2009) L. M. Lauffer et al. DIABETES
- Atypical Responsiveness of the Orphan Receptor GPR55 to Cannabinoid Ligands
- (2009) Ankur Kapur et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo
- (2009) L. S. Whyte et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Receptors for acylethanolamides—GPR55 and GPR119
- (2009) Grzegorz Godlewski et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release
- (2008) Zhi-Liang Chu et al. ENDOCRINOLOGY
- The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain
- (2008) Penny C. Staton et al. PAIN
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