Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons

Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease

(2018) Amandine Virlogeux et al.   Cell Reports

Corticostriatal synaptic adaptations in Huntington's disease

(2015) Joshua L Plotkin et al.   CURRENT OPINION IN NEUROBIOLOGY

Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease

(2015) Tim Indersmitten et al.   JOURNAL OF NEUROPHYSIOLOGY

The tumor suppressor PTEN regulates motor responses to striatal dopamine in normal and Parkinsonian animals

(2015) Mihaela A. Stavarache et al.   NEUROBIOLOGY OF DISEASE

Neurotrophin receptor p75NTR mediates Huntington’s disease–associated synaptic and memory dysfunction

(2014) Verónica Brito et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease

(2014) Nan Wang et al.   NATURE MEDICINE

Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington’s Disease

(2014) Joshua L. Plotkin et al.   NEURON

T-type channels buddy up

(2014) Ray W. Turner et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia

(2014) M. Heiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of dendritic calcium release in striatal spiny projection neurons

(2013) Joshua L. Plotkin et al.   JOURNAL OF NEUROPHYSIOLOGY

Convergent cortical innervation of striatal projection neurons

(2013) Geraldine J Kress et al.   NATURE NEUROSCIENCE

Imbalance of p75NTR/TrkB protein expression in Huntington’s disease: implication for neuroprotective therapies

(2013) V Brito et al.   Cell Death & Disease

Calcium leak through ryanodine receptor is involved in neuronal death induced by mutant huntingtin

(2012) Mari Suzuki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

(2012) Liliana B. Menalled et al.   PLoS One

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

(2012) Taneli Heikkinen et al.   PLoS One

Synthetic zinc finger repressors reduce mutant huntingtin expression in the brain of R6/2 mice

(2012) M. Garriga-Canut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of Striatal Projection Systems by Dopamine

(2011) Charles R. Gerfen et al.   Annual Review of Neuroscience

Differential Electrophysiological Changes in Striatal Output Neurons in Huntington's Disease

(2011) V. M. Andre et al.   JOURNAL OF NEUROSCIENCE

Dantrolene is neuroprotective in Huntington's disease transgenic mouse model

(2011) Xi Chen et al.   Molecular Neurodegeneration

Synaptically driven state transitions in distal dendrites of striatal spiny neurons

(2011) Joshua L Plotkin et al.   NATURE NEUROSCIENCE

Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels

(2011) Helene Vacher et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Impaired TrkB-mediated ERK1/2 Activation in Huntington Disease Knock-in Striatal Cells Involves Reduced p52/p46 Shc Expression

(2010) Silvia Ginés et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes

(2010) Dustin Anderson et al.   NATURE NEUROSCIENCE

Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors

(2010) Michael J Higley et al.   NATURE NEUROSCIENCE

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

(2010) Chiara Zuccato et al.   PHYSIOLOGICAL REVIEWS

Cell Type-Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward

(2010) M. K. Lobo et al.   SCIENCE

Alterations in Cortical Excitation and Inhibition in Genetic Mouse Models of Huntington's Disease

(2009) D. M. Cummings et al.   JOURNAL OF NEUROSCIENCE

The subcellular organization of neocortical excitatory connections

(2009) Leopoldo Petreanu et al.   NATURE

Kv4.2 is a locus for PKC and ERK/MAPK cross-talk

(2008) Laura A. Schrader et al.   BIOCHEMICAL JOURNAL

Chroman-3-amides as potent Rho kinase inhibitors

(2008) Yen Ting Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mechanisms of neurodegeneration in Huntington’s disease

(2008) Joana M. Gil et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Differential Excitability and Modulation of Striatal Medium Spiny Neuron Dendrites

(2008) M. Day et al.   JOURNAL OF NEUROSCIENCE

Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

(2008) M. Gray et al.   JOURNAL OF NEUROSCIENCE