Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development

标题
Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development
作者
关键词
pluripotent stem cells, endoderm, single-cell RNA-seq, CRISPRi, human development, chromatin accessibility, hepatic endoderm, dCas9-KRAB, stem cell differentiation, perturbation screen
出版物
Cell Reports
Volume 27, Issue 3, Pages 708-718.e10
出版商
Elsevier BV
发表日期
2019-04-16
DOI
10.1016/j.celrep.2019.03.076

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