The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans

Weight-loss diets and 2-y changes in circulating amino acids in 2 randomized intervention trials1–3

(2016) Yan Zheng et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Distal, not proximal, colonic acetate infusions promote fat oxidation and improve metabolic markers in overweight/obese men

(2016) C. M. van der Beek et al.   CLINICAL SCIENCE

Pediatric obesity is associated with an altered gut microbiota and discordant shifts inFirmicutespopulations

(2016) Alessandra Riva et al.   ENVIRONMENTAL MICROBIOLOGY

Active packaging with antifungal activities

(2016) N. Nguyen Van Long et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

(2016) Rachel J. Perry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nutrient Transporter Expression in the Jejunum in Relation to Body Mass Index in Patients Undergoing Bariatric Surgery

(2016) Brian Irving et al.   Nutrients

Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice

(2015) Vishal Singh et al.   Cell Metabolism

Suppression of hyperinsulinaemia in growing female mice provides long-term protection against obesity

(2015) Nicole M. Templeman et al.   DIABETOLOGIA

Islet α cells and glucagon—critical regulators of energy homeostasis

(2015) Jonathan E. Campbell et al.   Nature Reviews Endocrinology

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

(2014) Meric Erikci Ertunc et al.   JOURNAL OF LIPID RESEARCH

Propionic and butyric acids, formed in the caecum of rats fed highly fermentable dietary fibre, are reflected in portal and aortic serum

(2013) Greta Jakobsdottir et al.   BRITISH JOURNAL OF NUTRITION

Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production

(2013) Haiming Cao et al.   Cell Metabolism

Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production

(2012) Arya E. Mehran et al.   Cell Metabolism

Liver-Specific Disruption of the Murine Glucagon Receptor Produces  -Cell Hyperplasia: Evidence for a Circulating  -Cell Growth Factor

(2012) C. Longuet et al.   DIABETES

Diabetes: Have We Got It All Wrong?: Insulin hypersecretion and food additives: cause of obesity and diabetes?

(2012) B. E. Corkey   DIABETES CARE

Effects of a novel propionate-rich sourdough bread on appetite and food intake

(2012) J Darzi et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms

(2012) Hua V. Lin et al.   PLoS One

Propionate. Anti-obesity and satiety enhancing factor?

(2011) Tulika Arora et al.   APPETITE

Banting Lecture 2011: Hyperinsulinemia: Cause or Consequence?

(2011) B. E. Corkey   DIABETES

Propionic acid affects immune status and metabolism in adipose tissue from overweight subjects

(2011) Sa’ad Al-Lahham et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41)

(2011) I. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet

(2010) Mikael Bjursell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms

(2010) Sa'ad H. Al-Lahham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Regulation of adipokine production in human adipose tissue by propionic acid

(2010) Sa’ad H. Al-Lahham et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Gluconeogenesis in dairy cows: The secret of making sweet milk from sour dough

(2010) Jörg R. Aschenbach et al.   IUBMB LIFE

Dietary Energy Density and Weight Regulation

(2010) Manjiang Yao et al.   NUTRITION REVIEWS

Microbiota and SCFA in Lean and Overweight Healthy Subjects

(2009) Andreas Schwiertz et al.   Obesity

Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet

(2008) Iris Shai et al.   NEW ENGLAND JOURNAL OF MEDICINE