Autophagy mediates 2-methoxyestradiol-inhibited scleroderma collagen synthesis and endothelial-to-mesenchymal transition induced by hypoxia

TFEB and trehalose drive the macrophage autophagy-lysosome system to protect against atherosclerosis

(2018) Trent D. Evans et al.   Autophagy

The role of extracellular matrix components in angiogenesis and fibrosis: Possible implication for Systemic Sclerosis

(2018) Vasiliki Liakouli et al.   Modern Rheumatology

2-Methoxyestradiol inhibits hypoxia-induced scleroderma fibroblast collagen synthesis by phosphatidylinositol 3-kinase/Akt/mTOR signalling

(2018) Xing Zhou et al.   RHEUMATOLOGY

2-Methoxyestradiol

(2017) Raghvendra K. Dubey   HYPERTENSION

Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation

(2017) Nina Germic et al.   IMMUNOLOGY

Hypoxia-induced ADAM 17 expression is mediated by RSK1-dependent C/EBPβ activation in human lung fibroblasts

(2017) Jing-Yun Chen et al.   MOLECULAR IMMUNOLOGY

Retrograde signaling from autophagy modulates stress responses

(2017) Hans-Uwe Simon et al.   Science Signaling

Effects of 17β-estradiol and 2-methoxyestradiol on the oxidative stress-hypoxia inducible factor-1 pathway in hypoxic pulmonary hypertensive rats

(2017) Li Wang et al.   Experimental and Therapeutic Medicine

Retrograde signaling from autophagy modulates stress responses

(2017) Hans-Uwe Simon et al.   Science Signaling

Targeting Hypoxia Inducible Factors-1α As a Novel Therapy in Fibrosis

(2017) Anji Xiong et al.   Frontiers in Pharmacology

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Raynaud’s Phenomenon

(2016) Fredrick M. Wigley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recent Advances in chemistry and pharmacology of 2-methoxyestradiol: An anticancer investigational drug

(2016) B. Sathish Kumar et al.   STEROIDS

Signaling pathways and mechanisms of hypoxia-induced autophagy in the animal cells

(2015) Yungyun Fang et al.   CELL BIOLOGY INTERNATIONAL

Autophagy inhibitors

(2015) Benoit Pasquier   CELLULAR AND MOLECULAR LIFE SCIENCES

A Hypoxia-Induced Vascular Endothelial-to-Mesenchymal Transition in Development of Radiation-Induced Pulmonary Fibrosis

(2015) S.-H. Choi et al.   CLINICAL CANCER RESEARCH

2-Methoxyestradiol inhibits bleomycin-induced systemic sclerosis through suppression of fibroblast activation

(2015) Lubing Zhu et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Autophagy in autoimmune disease

(2015) Zhen Yang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease

(2015) Fabian A. Mendoza et al.   Arthritis & Rheumatology

2-Methoxyestradiol Attenuates Autophagy Activation After Global Ischemia

(2014) Xiao-Yu Xin et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative

(2013) Frank van den Hoogen et al.   ARTHRITIS AND RHEUMATISM

Autophagy is a key feature in the pathogenesis of systemic sclerosis

(2013) Tracy Frech et al.   RHEUMATOLOGY INTERNATIONAL

Characterization of the phenotype of high collagen-producing fibroblast clones in systemic sclerosis, using a new modified limiting-dilution method

(2012) L. Zhu et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Scleroderma-like properties of skin from caveolin-1-deficient mice

(2011) Remedios Castello-Cros et al.   CELL CYCLE

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS