Effect of tocilizumab, an interleukin-6 inhibitor, on early stage streptozotocin-induced diabetic nephropathy in rats

Effect of infliximab and tocilizumab on fructose-induced hyperinsulinemia and hypertension in rats

(2018) Aly M. Abdelrahman et al.   BIOMEDICINE & PHARMACOTHERAPY

Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction

(2018) Ola Kleveland et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

IL-6 receptor blockade ameliorates diabetic nephropathy via inhibiting inflammasome in mice

(2018) Rui Wu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The combination of IL-6 and its soluble receptor is associated with the response of rheumatoid arthritis patients to tocilizumab

(2018) Cesar Diaz-Torne et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Vitamin D protects against diabetic nephropathy: Evidence-based effectiveness and mechanism

(2018) Xiaofang Hu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective Effects of Tocilizumab on Experimentally-Induced Spinal Cord Ischemia-Reperfusion Injury

(2018) Yasar Karatas et al.   World Neurosurgery

Tocilizumab (Actemra)

(2017) Martin Sheppard et al.   Human Vaccines & Immunotherapeutics

IL-6 inhibitors for treatment of rheumatoid arthritis: past, present, and future

(2015) Go Woon Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Nitric oxide in the normal kidney and in patients with diabetic nephropathy

(2014) Paolo Tessari   JOURNAL OF NEPHROLOGY

Interleukin-6 in renal disease and therapy

(2014) S. A. Jones et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Dipeptidyl peptidase-4 inhibitor ameliorates early renal injury through its anti-inflammatory action in a rat model of type 1 diabetes

(2013) Ryo Kodera et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased nitric oxide activity compensates for increased oxidative stress to maintain endothelial function in rat aorta in early type 1 diabetes

(2013) A. Joshi et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Effect of Interleukin 6 Deficiency on Renal Interstitial Fibrosis

(2012) Jun Yang et al.   PLoS One

Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes

(2011) R. Kodera et al.   DIABETOLOGIA

Interleukin 6 Underlies Angiotensin II–Induced Hypertension and Chronic Renal Damage

(2011) Weiru Zhang et al.   HYPERTENSION

Impaired Tubular Uptake Explains Albuminuria in Early Diabetic Nephropathy

(2009) L. M. Russo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Four-week administration of nimesulide, a cyclooxygenase-2 inhibitor, improves endothelial dysfunction in the hindlimb vasculature of streptozotocin-induced diabetic rats

(2008) Aly M. Abdelrahman et al.   ARCHIVES OF PHARMACAL RESEARCH

Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease

(2008) N. Nishimoto et al.   BLOOD

IL-6/IL-6R Axis Plays a Critical Role in Acute Kidney Injury

(2008) Y. Nechemia-Arbely et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY