The cryo-EM method microcrystal electron diffraction (MicroED)

Collection of Continuous Rotation MicroED Data from Ion Beam-Milled Crystals of Any Size

(2019) Michael W. Martynowycz et al.   STRUCTURE

MicroED data collection with SerialEM

(2019) M. Jason de la Cruz et al.   ULTRAMICROSCOPY

An Extra-Large-Pore Zeolite with 24×8×8-Ring Channels Using a Structure-Directing Agent Derived from Traditional Chinese Medicine

(2018) Chuanqi Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation

(2018) Elizabeth L. Guenther et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp

(2018) Marcus Gallagher-Jones et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation

(2018) Feng Luo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser

(2018) Przemyslaw Nogly et al.   SCIENCE

Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks

(2018) Michael P. Hughes et al.   SCIENCE

Analysis of Global and Site-Specific Radiation Damage in Cryo-EM

(2018) Johan Hattne et al.   STRUCTURE

Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation

(2018) Elizabeth L. Guenther et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp

(2018) Marcus Gallagher-Jones et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation

(2018) Feng Luo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Electron diffraction data processing with DIALS

(2018) Max T. B. Clabbers et al.   Acta Crystallographica Section D-Structural Biology

X-ray lasers for structure and dynamics in biology

(2018) John C. H. Spence   IUCrJ

Machining protein microcrystals for structure determination by electron diffraction

(2018) Helen M. E. Duyvesteyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Structure Determination of Microcrystalline Molecular Compounds Using Electron Diffraction

(2018) Tim Gruene et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat

(2018) Michael D. Purdy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The CryoEM Method MicroED as a Powerful Tool for Small Molecule Structure Determination

(2018) Christopher G. Jones et al.   ACS Central Science

Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors

(2017) Pascal Krotee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroED Structure of Au146(p-MBA)57 at Subatomic Resolution Reveals a Twinned FCC Cluster

(2017) Sandra Vergara et al.   Journal of Physical Chemistry Letters

Structure-based inhibitors of tau aggregation

(2017) P. M. Seidler et al.   Nature Chemistry

Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED

(2017) M Jason de la Cruz et al.   NATURE METHODS

Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity

(2017) Pascal Krotee et al.   eLife

Protein structure determination by electron diffraction using a single three-dimensional nanocrystal

(2017) M. T. B. Clabbers et al.   Acta Crystallographica Section D-Structural Biology

Protein microcrystallography using synchrotron radiation

(2017) Masaki Yamamoto et al.   IUCrJ

Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond crystallography

(2016) Christopher O. Barnes et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Serial femtosecond crystallography: A revolution in structural biology

(2016) Jose M. Martin-Garcia et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

MicroED opens a new era for biological structure determination

(2016) Brent L Nannenga et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Ultrafast Electron Diffraction Tomography for Structure Determination of the New Zeolite ITQ-58

(2016) Jorge Simancas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The collection of MicroED data for macromolecular crystallography

(2016) Dan Shi et al.   Nature Protocols

Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED

(2016) Michael R. Sawaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein

(2016) K. Pande et al.   SCIENCE

Cryo-Electron Tomography: Can it Reveal the Molecular Sociology of Cells in Atomic Detail?

(2016) Martin Beck et al.   TRENDS IN CELL BIOLOGY

Crystal structure of an HIV assembly and maturation switch

(2016) Jonathan M Wagner et al.   eLife

Ab initiostructure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector

(2016) E. van Genderen et al.   Acta Crystallographica A-Foundation and Advances

Lattice filter for processing image data of three-dimensional protein nanocrystals

(2016) E. van Genderen et al.   Acta Crystallographica Section D-Structural Biology

Transmission electron microscopy for the evaluation and optimization of crystal growth

(2016) Hilary P. Stevenson et al.   Acta Crystallographica Section D-Structural Biology

Modeling truncated pixel values of faint reflections in MicroED images

(2016) Johan Hattne et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

A Primer to Single-Particle Cryo-Electron Microscopy

(2015) Yifan Cheng et al.   CELL

Structure of the toxic core of α-synuclein from invisible crystals

(2015) Jose A. Rodriguez et al.   NATURE

2.2 A resolution cryo-EM structure of  -galactosidase in complex with a cell-permeant inhibitor

(2015) A. Bartesaghi et al.   SCIENCE

Solving protein nanocrystals by cryo-EM diffraction: Multiple scattering artifacts

(2015) Ganesh Subramanian et al.   ULTRAMICROSCOPY

MicroED data collection and processing

(2015) Johan Hattne et al.   Acta Crystallographica A-Foundation and Advances

Precession electron diffraction – a topical review

(2015) Paul A. Midgley et al.   IUCrJ

High-resolution structure determination by continuous-rotation data collection in MicroED

(2014) Brent L Nannenga et al.   NATURE METHODS

Use of transmission electron microscopy to identify nanocrystals of challenging protein targets

(2014) H. P. Stevenson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of catalase determined by MicroED

(2014) Brent L Nannenga et al.   eLife

A suite of software for processing MicroED data of extremely small protein crystals

(2014) Matthew G. Iadanza et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Imaging protein three-dimensional nanocrystals with cryo-EM

(2013) Igor Nederlof et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A Medipix quantum area detector allows rotation electron diffraction data collection from submicrometre three-dimensional protein crystals

(2013) Igor Nederlof et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Three-dimensional rotation electron diffraction: softwareREDfor automated data collection and data processing

(2013) Wei Wan et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Single-Crystal Structure of a Covalent Organic Framework

(2013) Yue-Biao Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mix and Inject: Reaction Initiation by Diffusion for Time-Resolved Macromolecular Crystallography

(2013) Marius Schmidt   Advances in Condensed Matter Physics

Three-dimensional electron crystallography of protein microcrystals

(2013) Dan Shi et al.   eLife

Ab-initiocrystal structure analysis and refinement approaches of oligop-benzamides based on electron diffraction data

(2012) Tatiana E. Gorelik et al.   ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

Automated Diffraction Tomography for the Structure Elucidation of Twinned, Sub-micrometer Crystals of a Highly Porous, Catalytically Active Bismuth Metal-Organic Framework

(2012) Mark Feyand et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ab Initio Structure Determination of Vaterite by Automated Electron Diffraction

(2012) Enrico Mugnaioli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Micro-crystallography comes of age

(2012) Janet L Smith et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Gating Movement of Acetylcholine Receptor Caught by Plunge-Freezing

(2012) Nigel Unwin et al.   JOURNAL OF MOLECULAR BIOLOGY

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Second-Order Nonlinear Optical Imaging of Chiral Crystals

(2011) David J. Kissick et al.   Annual Review of Analytical Chemistry

Automated electron diffraction tomography - a new tool for nano crystal structure analysis

(2011) U. Kolb et al.   CRYSTAL RESEARCH AND TECHNOLOGY

Femtosecond nanocrystallography using X-ray lasers for membrane protein structure determination

(2011) Petra Fromme et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structure solution with automated electron diffraction tomography data: different instrumental approaches

(2011) T.E. GORELIK et al.   JOURNAL OF MICROSCOPY

Synthesis and Structure Determination of the Hierarchical Meso-Microporous Zeolite ITQ-43

(2011) J. Jiang et al.   SCIENCE

Advances in Structural and Functional Analysis of Membrane Proteins by Electron Crystallography

(2011) Goragot Wisedchaisri et al.   STRUCTURE

Insights into the molecular organization of the neuron by cryo-electron tomography

(2011) R. Fernandez-Busnadiego et al.   Microscopy

Radiation damage in macromolecular crystallography: what is it and why should we care?

(2010) Elspeth F. Garman   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Unit-cell determination from randomly oriented electron-diffraction patterns

(2009) Linhua Jiang et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

“Ab initio” structure solution from electron diffraction data obtained by a combination of automated diffraction tomography and precession technique

(2009) E. Mugnaioli et al.   ULTRAMICROSCOPY