SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis

Hyposialylated IgG activates endothelial IgG receptor FcγRIIB to promote obesity-induced insulin resistance

(2017) Keiji Tanigaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice

(2017) Shunxing Rong et al.   eLife

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1

(2017) Karen Y. Fung et al.   Frontiers in Physiology

Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice

(2016) Keiji Tanigaki et al.   DIABETES

Control of cerebral ischemia with magnetic nanoparticles

(2016) Jie-Min Jia et al.   NATURE METHODS

Genome-wide RNAi screen reveals ALK1 mediates LDL uptake and transcytosis in endothelial cells

(2016) Jan R. Kraehling et al.   Nature Communications

Scavenger receptor B1, the HDL receptor, is expressed abundantly in liver sinusoidal endothelial cells

(2016) Latha P. Ganesan et al.   Scientific Reports

A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis

(2015) Susan M. Armstrong et al.   CARDIOVASCULAR RESEARCH

Recent insights into the cellular biology of atherosclerosis

(2015) Ira Tabas et al.   JOURNAL OF CELL BIOLOGY

MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

(2015) Mireille Ouimet et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice

(2015) LinZhang Huang et al.   JOURNAL OF LIPID RESEARCH

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice

(2015) Boris L. Vaisman et al.   Biomed Research International

Endothelial caveolin-1 plays a major role in the development of atherosclerosis

(2014) Stephanos Pavlides et al.   CELL AND TISSUE RESEARCH

The Cholesterol Metabolite 27-Hydroxycholesterol Promotes Atherosclerosis via Proinflammatory Processes Mediated by Estrogen Receptor Alpha

(2014) Michihisa Umetani et al.   Cell Metabolism

Biomechanical factors in atherosclerosis: mechanisms and clinical implications

(2014) Brenda R. Kwak et al.   EUROPEAN HEART JOURNAL

Dock-family exchange factors in cell migration and disease

(2014) Gilles Gadea et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Relative roles ofABCG5/ABCG8in liver and intestine

(2014) Jin Wang et al.   JOURNAL OF LIPID RESEARCH

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation

(2014) Raphaël Duivenvoorden et al.   Nature Communications

Lymphatic Vessels Are Essential for the Removal of Cholesterol from Peripheral Tissues by SR-BI-Mediated Transport of HDL

(2013) Hwee Ying Lim et al.   Cell Metabolism

Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

(2013) Dante Neculai et al.   NATURE

Cholesterol Efflux and Atheroprotection

(2012) Robert S. Rosenson et al.   CIRCULATION

Novel Biological Functions of High-Density Lipoprotein Cholesterol

(2012) Chieko Mineo et al.   CIRCULATION RESEARCH

Scavenger Receptor Class B Type I Is a Plasma Membrane Cholesterol Sensor

(2012) Sonika Saddar et al.   CIRCULATION RESEARCH

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Co-Regulation of Transcellular and Paracellular Leak Across Microvascular Endothelium by Dynamin and Rac

(2011) Susan M. Armstrong et al.   AMERICAN JOURNAL OF PATHOLOGY

Comparative evaluation of label-free SINQ normalized spectral index quantitation in the central proteomics facilities pipeline

(2011) David C. Trudgian et al.   PROTEOMICS

CPFP: a central proteomics facilities pipeline

(2010) D. C. Trudgian et al.   BIOINFORMATICS

Lipoprotein receptors – an evolutionarily ancient multifunctional receptor family

(2010) Marco Dieckmann et al.   BIOLOGICAL CHEMISTRY

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

(2010) Yuefeng Tang et al.   GENESIS

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Genetic Evidence Supporting a Critical Role of Endothelial Caveolin-1 during the Progression of Atherosclerosis

(2009) Carlos Fernández-Hernando et al.   Cell Metabolism

Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown

(2009) Y. Baumer et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cell Migration Is Regulated by Platelet-Derived Growth Factor Receptor Endocytosis

(2009) K. Kawada et al.   MOLECULAR AND CELLULAR BIOLOGY

Transient Increase in Plasma Oxidized LDL During the Progression of Atherosclerosis in Apolipoprotein E Knockout Mice

(2008) Rina Kato et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impact of Plasma Oxidized Low-Density Lipoprotein Removal on Atherosclerosis

(2008) Yasushi Ishigaki et al.   CIRCULATION