Combined cellomics and proteomics analysis reveals shared neuronal morphology and molecular pathway phenotypes for multiple schizophrenia risk genes

Building a schizophrenia genetic network: Transcription Factor 4 regulates genes involved in neuronal development and schizophrenia risk

(2018) Hanzhang Xia et al.   HUMAN MOLECULAR GENETICS

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

Tcf4 regulates dendritic spine density and morphology in the adult brain

(2018) Sophie Crux et al.   PLoS One

Comparative Analyses of Data Independent Acquisition Mass Spectrometric Approaches: DIA, WiSIM-DIA, and Untargeted DIA

(2018) Frank Koopmans et al.   PROTEOMICS

Association study and mutation sequencing of genes on chromosome 15q11-q13 identified GABRG3 as a susceptibility gene for autism in Chinese Han population

(2018) Linyan Wang et al.   Translational Psychiatry

Comparative Hippocampal Synaptic Proteomes of Rodents and Primates: Differences in Neuroplasticity-Related Proteins

(2018) Frank Koopmans et al.   Frontiers in Molecular Neuroscience

Truncating mutations in RBM12 are associated with psychosis

(2017) Stacy Steinberg et al.   NATURE GENETICS

Genetic insights into the neurodevelopmental origins of schizophrenia

(2017) Rebecca Birnbaum et al.   NATURE REVIEWS NEUROSCIENCE

A part of patients with autism spectrum disorder has haploidy of HPC-1/syntaxin1A gene that possibly causes behavioral disturbance as in experimentally gene ablated mice

(2017) Takefumi Kofuji et al.   NEUROSCIENCE LETTERS

The Psychiatric Risk Gene Transcription Factor 4 (TCF4) Regulates Neurodevelopmental Pathways Associated With Schizophrenia, Autism, and Intellectual Disability

(2017) Marc P Forrest et al.   SCHIZOPHRENIA BULLETIN

Genome-Wide Association Study of Psychosis Proneness in the Finnish Population

(2017) Alfredo Ortega-Alonso et al.   SCHIZOPHRENIA BULLETIN

An Integrative Computational Approach to Evaluate Genetic Markers for Bipolar Disorder

(2017) Yong Xu et al.   Scientific Reports

Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder

(2017) Tom S. Koemans et al.   PLoS Genetics

Genetic predictors of antipsychotic response to lurasidone identified in a genome wide association study and by schizophrenia risk genes

(2017) Jiang Li et al.   SCHIZOPHRENIA RESEARCH

Disruption of POGZ Is Associated with Intellectual Disability and Autism Spectrum Disorders

(2016) Holly A.F. Stessman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A de novo frameshift mutation in chromodomain helicase DNA-binding domain 8 (CHD8): A case report and literature review

(2016) Nancy Merner et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons

(2016) Gülçin Vardar et al.   JOURNAL OF NEUROSCIENCE

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

(2016) Christian R Marshall et al.   NATURE GENETICS

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

(2016) Tarjinder Singh et al.   NATURE NEUROSCIENCE

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

(2016) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

Analysis of the association of VIPR2 polymorphisms with susceptibility to schizophrenia

(2016) Chunhui Jin et al.   PSYCHIATRY RESEARCH

Identification of the BRD1 interaction network and its impact on mental disorder risk

(2016) Tue Fryland et al.   Genome Medicine

Resequencing and Association Analysis of Six PSD-95-Related Genes as Possible Susceptibility Genes for Schizophrenia and Autism Spectrum Disorders

(2016) Jingrui Xing et al.   Scientific Reports

Genetic Risk for Schizophrenia: Convergence on Synaptic Pathways Involved in Plasticity

(2015) Jeremy Hall et al.   BIOLOGICAL PSYCHIATRY

Fitting Linear Mixed-Effects Models Usinglme4

(2015) Douglas Bates et al.   Journal of Statistical Software

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms

(2015) Alissa M. D’Gama et al.   NEURON

Copy number variant study of bipolar disorder in Canadian and UK populations implicates synaptic genes

(2014) Abdul Noor et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

(2014) Wei Xu et al.   BMC Medical Genetics

Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia

(2014) M Föcking et al.   MOLECULAR PSYCHIATRY

Synaptic, transcriptional and chromatin genes disrupted in autism

(2014) Silvia De Rubeis et al.   NATURE

A polygenic burden of rare disruptive mutations in schizophrenia

(2014) Shaun M. Purcell et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality

(2014) Tzyy-Nan Huang et al.   NATURE NEUROSCIENCE

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Genetic analysis of GABRB3 at 15q12 as a candidate gene of schizophrenia

(2014) Chia-Chun Huang et al.   PSYCHIATRIC GENETICS

The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder

(2014) Niamh L. O’Brien et al.   PSYCHIATRIC GENETICS

Neuronal excitation upregulates Tbr1, a high-confidence risk gene of autism, mediating Grin2b expression in the adult brain

(2014) Hsiu-Chun Chuang et al.   Frontiers in Cellular Neuroscience

Transcriptional targets of the schizophrenia risk gene MIR137

(2014) A L Collins et al.   Translational Psychiatry

Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells

(2014) Diana Xuan Yu et al.   Stem Cell Reports

The genomics of schizophrenia: update and implications

(2013) Paola Giusti-Rodríguez et al.   JOURNAL OF CLINICAL INVESTIGATION

Revisiting DARPP-32 in postmortem human brain: changes in schizophrenia and bipolar disorder and genetic associations with t-DARPP-32 expression

(2013) Y Kunii et al.   MOLECULAR PSYCHIATRY

Autophagy has a key role in the pathophysiology of schizophrenia

(2013) A Merenlender-Wagner et al.   MOLECULAR PSYCHIATRY

Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formation

(2013) Dongyi Xu et al.   NATURE NEUROSCIENCE

Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

(2013) Georg Stoll et al.   NATURE NEUROSCIENCE

FMRP targets distinct mRNA sequence elements to regulate protein expression

(2012) Manuel Ascano et al.   NATURE

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex

(2012) Gerard M J Beaudoin et al.   Nature Protocols

Support for calcium channel gene defects in autism spectrum disorders

(2012) Ake Tzu-Hui Lu et al.   Molecular Autism

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia

(2011) Vladimir Vacic et al.   NATURE

Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia

(2010) A Piton et al.   MOLECULAR PSYCHIATRY

Genome-wide association study of bipolar I disorder in the Han Chinese population

(2010) M T M Lee et al.   MOLECULAR PSYCHIATRY

Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex

(2010) F. Bedogni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication of an association of a common variant in the Reelin gene (RELN) with schizophrenia in Ashkenazi Jewish women

(2010) Yaping Liu et al.   PSYCHIATRIC GENETICS

A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder

(2010) Ke-Sheng Wang et al.   SCHIZOPHRENIA RESEARCH

Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

(2008) Gary J. Bassell et al.   NEURON