HIV-1 restriction by endogenous APOBEC3G in the myeloid cell line THP-1

Vif-CBFβ interaction is essential for Vif-induced cell cycle arrest

(2019) Juan Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

HIV and the Macrophage: From Cell Reservoirs to Drug Delivery to Viral Eradication

(2018) Jonathan Herskovitz et al.   Journal of Neuroimmune Pharmacology

The Biology of Monocytes and Dendritic Cells: Contribution to HIV Pathogenesis

(2018) Vanessa Wacleche et al.   Viruses-Basel

HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G

(2018) Terumasa Ikeda et al.   PLoS Pathogens

HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction

(2018) Siobhan Gargan et al.   EBioMedicine

A lentivirus-based system for Cas9/gRNA expression and subsequent removal by Cre-mediated recombination

(2018) Michael A. Carpenter et al.   METHODS

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor

(2017) Rachel S. Leibman et al.   PLoS Pathogens

Identification of Interferon-Stimulated Genes with Antiretroviral Activity

(2016) Melissa Kane et al.   Cell Host & Microbe

Macrophages and HIV-1: An Unhealthy Constellation

(2016) Quentin J. Sattentau et al.   Cell Host & Microbe

Contribution of APOBEC3G/F activity to the development of low-abundance drug-resistant human immunodeficiency virus type 1 variants

(2016) M. Noguera-Julian et al.   CLINICAL MICROBIOLOGY AND INFECTION

The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers

(2015) Brandon Leonard et al.   CANCER RESEARCH

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape

(2015) Viviana Simon et al.   NATURE IMMUNOLOGY

APOBECs and virus restriction

(2015) Reuben S. Harris et al.   VIROLOGY

Transcriptional regulation of APOBEC3 antiviral immunity through the CBF- /RUNX axis

(2015) B. D. Anderson et al.   Science Advances

Role of myeloid cells in HIV-1-host interplay

(2014) Mario Stevenson   JOURNAL OF NEUROVIROLOGY

Natural Polymorphisms in Human APOBEC3H and HIV-1 Vif Combine in Primary T Lymphocytes to Affect Viral G-to-A Mutation Levels and Infectivity

(2014) Eric W. Refsland et al.   PLoS Genetics

APOBEC3D and APOBEC3F Potently Promote HIV-1 Diversification and Evolution in Humanized Mouse Model

(2014) Kei Sato et al.   PLoS Pathogens

Human APOBEC3 Induced Mutation of Human Immunodeficiency Virus Type-1 Contributes to Adaptation and Evolution in Natural Infection

(2014) Eun-Young Kim et al.   PLoS Pathogens

AID and APOBECs span the gap between innate and adaptive immunity

(2014) Arnaud Moris et al.   Frontiers in Microbiology

HIV-1 Vif Adaptation to Human APOBEC3H Haplotypes

(2013) Marcel Ooms et al.   Cell Host & Microbe

Endogenous APOBEC3A DNA Cytosine Deaminase Is Cytoplasmic and Nongenotoxic

(2013) Allison M. Land et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IFN-  Induces APOBEC3G, F, and A in Immature Dendritic Cells and Limits HIV-1 Spread to CD4+ T Cells

(2013) V. Mohanram et al.   JOURNAL OF IMMUNOLOGY

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

APOBEC3B is an enzymatic source of mutation in breast cancer

(2013) Michael B. Burns et al.   NATURE

HIV Restriction Factors and Mechanisms of Evasion

(2013) M. H. Malim et al.   Cold Spring Harbor Perspectives in Medicine

APOBEC3G Restricts HIV-1 to a Greater Extent than APOBEC3F and APOBEC3DE in Human Primary CD4+ T Cells and Macrophages

(2012) C. Chaipan et al.   JOURNAL OF VIROLOGY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Endogenous Origins of HIV-1 G-to-A Hypermutation and Restriction in the Nonpermissive T Cell Line CEM2n

(2012) Eric W. Refsland et al.   PLoS Pathogens

Human and Rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H Demonstrate a Conserved Capacity To Restrict Vif-Deficient HIV-1

(2011) J. F. Hultquist et al.   JOURNAL OF VIROLOGY

Target Cell-Mediated Editing of HIV-1 cDNA by APOBEC3 Proteins in Human Macrophages

(2011) F. A. Koning et al.   JOURNAL OF VIROLOGY

T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction

(2011) Wenyan Zhang et al.   NATURE

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

(2011) Stefanie Jäger et al.   NATURE

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

APOBEC3A Is a Specific Inhibitor of the Early Phases of HIV-1 Infection in Myeloid Cells

(2011) Gregory Berger et al.   PLoS Pathogens

Innate Immune Signaling Induces High Levels of TC-specific Deaminase Activity in Primary Monocyte-derived Cells through Expression of APOBEC3A Isoforms

(2010) Beth K. Thielen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Specific Determinants of Human APOBEC3F, APOBEC3C, and APOBEC3DE and African Green Monkey APOBEC3F That Interact with HIV-1 Vif

(2010) J. L. Smith et al.   JOURNAL OF VIROLOGY

Human APOBEC3G-Mediated Editing Can Promote HIV-1 Sequence Diversification and Accelerate Adaptation to Selective Pressure

(2010) E.-Y. Kim et al.   JOURNAL OF VIROLOGY

Long-Term Restriction by APOBEC3F Selects Human Immunodeficiency Virus Type 1 Variants with Restored Vif Function

(2010) J. S. Albin et al.   JOURNAL OF VIROLOGY

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

(2010) Mark D Stenglein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

(2010) Eric W. Refsland et al.   NUCLEIC ACIDS RESEARCH

CCR6 ligands inhibit HIV by inducing APOBEC3G

(2009) M. K. Lafferty et al.   BLOOD

Evidence that Ecotropic Murine Leukemia Virus Contamination in TZM-bl Cells Does Not Affect the Outcome of Neutralizing Antibody Assays with Human Immunodeficiency Virus Type 1

(2009) E. J. Platt et al.   JOURNAL OF VIROLOGY

Defining APOBEC3 Expression Patterns in Human Tissues and Hematopoietic Cell Subsets

(2009) F. A. Koning et al.   JOURNAL OF VIROLOGY

Likely Role of APOBEC3G-Mediated G-to-A Mutations in HIV-1 Evolution and Drug Resistance

(2009) Patric Jern et al.   PLoS Pathogens

Antiretroelement Activity of APOBEC3H Was Lost Twice in Recent Human Evolution

(2008) Molly OhAinle et al.   Cell Host & Microbe

Evolution of HIV-1 Isolates that Use a Novel Vif-Independent Mechanism to Resist Restriction by Human APOBEC3G

(2008) Guylaine Haché et al.   CURRENT BIOLOGY

Distinct Domains within APOBEC3G and APOBEC3F Interact with Separate Regions of Human Immunodeficiency Virus Type 1 Vif

(2008) R. A. Russell et al.   JOURNAL OF VIROLOGY

Cytidine deamination induced HIV-1 drug resistance

(2008) L. C. F. Mulder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA